CA2834710A1 - Compositions and methods for the treatment of skin diseases - Google Patents

Compositions and methods for the treatment of skin diseases Download PDF

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Publication number
CA2834710A1
CA2834710A1 CA2834710A CA2834710A CA2834710A1 CA 2834710 A1 CA2834710 A1 CA 2834710A1 CA 2834710 A CA2834710 A CA 2834710A CA 2834710 A CA2834710 A CA 2834710A CA 2834710 A1 CA2834710 A1 CA 2834710A1
Authority
CA
Canada
Prior art keywords
ethanol
embodiment provides
another embodiment
composition
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2834710A
Other languages
English (en)
French (fr)
Inventor
Dale L. Pearlman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2834710A1 publication Critical patent/CA2834710A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2834710A 2011-05-16 2012-05-08 Compositions and methods for the treatment of skin diseases Abandoned CA2834710A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161486644P 2011-05-16 2011-05-16
US61/486,644 2011-05-16
US201261612203P 2012-03-16 2012-03-16
US61/612,203 2012-03-16
PCT/US2012/036966 WO2012158405A2 (en) 2011-05-16 2012-05-08 Compositions and methods for the treatment of skin diseases

Publications (1)

Publication Number Publication Date
CA2834710A1 true CA2834710A1 (en) 2012-11-22

Family

ID=47177559

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2834710A Abandoned CA2834710A1 (en) 2011-05-16 2012-05-08 Compositions and methods for the treatment of skin diseases

Country Status (5)

Country Link
US (1) US20130123221A1 (enExample)
EP (1) EP2709632A4 (enExample)
JP (1) JP2014516962A (enExample)
CA (1) CA2834710A1 (enExample)
WO (1) WO2012158405A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8580286B2 (en) * 2012-03-16 2013-11-12 Dale L. Pearlman Compositions and methods for the treatment of skin diseases
US10111956B2 (en) 2013-06-03 2018-10-30 Tolmar, Inc. Corticosteroid compositions
WO2015127390A1 (en) 2014-02-21 2015-08-27 Avadim Technologies, Inc. Method for maintenance of urethral catheters
CN104473865A (zh) * 2014-11-17 2015-04-01 重庆华邦制药有限公司 地奈德凝胶剂及其制备方法
CA2968525A1 (en) * 2014-11-19 2016-05-26 Avadim Technologies, Inc. Method for the prevention and treatment of acne
EP3982909A4 (en) 2019-06-12 2023-11-29 Avadim Health, Inc. COMPOSITIONS AND METHODS FOR ANTISEPTIC TREATMENT OF BIOFILMS ON MAMMALIAN TISSUE
CN112263542B (zh) * 2020-10-19 2023-09-01 澳美制药厂有限公司 地奈德纳米乳凝胶组合物及其制备方法
CN116059157B (zh) * 2022-12-29 2025-02-18 江苏知原药业股份有限公司 一种地奈德乳膏的制备工艺

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4185100A (en) * 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
US4147770A (en) * 1976-12-27 1979-04-03 Scholl, Inc. Preparation for treating dermatitis in the nature of tinea pedis
US4954487A (en) * 1979-01-08 1990-09-04 The Procter & Gamble Company Penetrating topical pharmaceutical compositions
US4246261A (en) * 1979-08-09 1981-01-20 Scott Eugene J Van Additives enhancing topical corticosteroid action
JPS5750914A (en) * 1980-09-12 1982-03-25 Shionogi & Co Ltd Betamethasone external pharmaceutical
JPS58185514A (ja) * 1982-04-22 1983-10-29 Hisamitsu Pharmaceut Co Inc 新規な局所用消炎鎮痛ゲル状クリ−ム剤
US4552872A (en) * 1983-06-21 1985-11-12 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing corticosteroids
JPS6013711A (ja) * 1983-06-21 1985-01-24 ザ、プロクタ−、エンド、ギヤンブル、カンパニ− コルチコステロイドを含有する浸透局所製薬組成物
MY102980A (en) * 1986-10-31 1993-03-31 Pfizer Transdermal flux enhancing compositions
EP0325949B1 (en) * 1988-01-13 1991-12-18 Schwarz Pharma Ag Concentrated solutions of corticosteroids and method of making them
JPH05286860A (ja) * 1992-04-03 1993-11-02 Kowa Co ゲル軟膏剤
CA2151774C (en) * 1994-06-27 1999-04-06 Minh Quang Hoang Skin disinfecting formulations
US5486537A (en) * 1995-01-20 1996-01-23 Dayton Laboratories, Inc. Topical anti-fungal composition for skin and keratinous tissue
GB9504265D0 (en) * 1995-03-03 1995-04-19 Medeva Plc Corticosteroid-containing pharmaceutical composition
US6238683B1 (en) * 1998-12-04 2001-05-29 Johnson & Johnson Consumer Companies, Inc. Anhydrous topical skin preparations
JP3448006B2 (ja) * 2000-03-29 2003-09-16 独立行政法人食品総合研究所 機能性エマルション
CA2505407A1 (en) * 2002-12-12 2004-06-24 Galderma Research & Development, S.N.C. Aqueous-alcoholic depigmenting gel containing a phenolic derivative and a retinoid
FR2850866B1 (fr) * 2003-02-06 2007-04-20 Seppic Sa Melange de latex inverse auto-inversible et d'une poudre a usage cosmetique ou pharmaceutique; utilisation comme agent de texture
US20050069499A1 (en) * 2003-09-25 2005-03-31 Moshe Arkin Foamable compositions, processes of preparing same and uses thereof
US20050196450A1 (en) * 2004-03-04 2005-09-08 Elka Touitou Method and composition for burned skin
CA2601694A1 (en) * 2005-03-14 2006-09-21 Macrochem Corporation Enhancement of macrolide penetration through human skin
JP5111117B2 (ja) * 2005-12-22 2012-12-26 興和株式会社 ステロイドの経時的安定性が改善された外用製剤
JP2007217394A (ja) * 2006-02-16 2007-08-30 I-Nage:Kk 医薬組成物
ES2543209T3 (es) * 2009-09-24 2015-08-17 Evonik Degussa Gmbh Polisiloxanos reticulados, proceso para su preparación y uso de los polisiloxanos reticulados en sistemas emulgentes para emulsiones de agua en aceite

Also Published As

Publication number Publication date
EP2709632A4 (en) 2015-03-04
JP2014516962A (ja) 2014-07-17
EP2709632A2 (en) 2014-03-26
WO2012158405A2 (en) 2012-11-22
US20130123221A1 (en) 2013-05-16
WO2012158405A3 (en) 2014-05-01

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20170510