CA2833559A1 - Treatment of conditions associated with decreased nitric oxide bioavailability, including elevated arginase conditions - Google Patents
Treatment of conditions associated with decreased nitric oxide bioavailability, including elevated arginase conditions Download PDFInfo
- Publication number
- CA2833559A1 CA2833559A1 CA2833559A CA2833559A CA2833559A1 CA 2833559 A1 CA2833559 A1 CA 2833559A1 CA 2833559 A CA2833559 A CA 2833559A CA 2833559 A CA2833559 A CA 2833559A CA 2833559 A1 CA2833559 A1 CA 2833559A1
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- Canada
- Prior art keywords
- arginine
- subject
- arginase
- composition
- nitric oxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A—HUMAN NECESSITIES
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Landscapes
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| US44737303P | 2003-02-14 | 2003-02-14 | |
| US60/447,373 | 2003-02-14 | ||
| CA2515929A CA2515929C (en) | 2003-02-14 | 2004-02-13 | Treatment of conditions associated with decreased nitric oxide bioavailability, including elevated arginase conditions |
Related Parent Applications (1)
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| CA2515929A Division CA2515929C (en) | 2003-02-14 | 2004-02-13 | Treatment of conditions associated with decreased nitric oxide bioavailability, including elevated arginase conditions |
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| CA2833559A1 true CA2833559A1 (en) | 2004-09-02 |
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| WO (1) | WO2004073623A2 (https=) |
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| MXPA05009251A (es) * | 2003-03-04 | 2005-10-19 | Wyeth Corp | Composiciones y metodos para diagnosticar y tratar asma u otras enfermedades alergicas o inflamatorias. |
| WO2005107384A2 (en) * | 2004-03-31 | 2005-11-17 | Nitromed, Inc. | Methods for treating blood disorders with nitric oxide donor compounds |
| WO2006049286A1 (ja) * | 2004-11-02 | 2006-05-11 | Ajinomoto Co., Inc. | アレルギー性疾患予防・治療剤 |
| ATE517347T1 (de) | 2004-12-01 | 2011-08-15 | Childrens Hosp & Res Ct Oak | Diagnose von leiden in zusammenhang mit verminderter arginin-bioverfügbarkeit |
| WO2007005620A2 (en) * | 2005-07-01 | 2007-01-11 | The Johns Hopkins University | Arginase ii: a target treatment of aging heart and heart failure |
| US10042980B2 (en) | 2005-11-17 | 2018-08-07 | Gearbox Llc | Providing assistance related to health |
| US8532938B2 (en) | 2005-11-17 | 2013-09-10 | The Invention Science Fund I, Llc | Testing-dependent administration of a nutraceutical |
| US7827042B2 (en) | 2005-11-30 | 2010-11-02 | The Invention Science Fund I, Inc | Methods and systems related to transmission of nutraceutical associated information |
| US20080103746A1 (en) | 2005-11-30 | 2008-05-01 | Searete Llc, A Limited Liability Corporation | Systems and methods for pathogen detection and response |
| US10296720B2 (en) | 2005-11-30 | 2019-05-21 | Gearbox Llc | Computational systems and methods related to nutraceuticals |
| US7927787B2 (en) | 2006-06-28 | 2011-04-19 | The Invention Science Fund I, Llc | Methods and systems for analysis of nutraceutical associated components |
| US8340944B2 (en) | 2005-11-30 | 2012-12-25 | The Invention Science Fund I, Llc | Computational and/or control systems and methods related to nutraceutical agent selection and dosing |
| US20070299693A1 (en) * | 2006-06-23 | 2007-12-27 | Searete Llc, A Limited Liability Corporation | Customized visual marking for medication labeling |
| US7974856B2 (en) * | 2005-11-30 | 2011-07-05 | The Invention Science Fund I, Llc | Computational systems and methods related to nutraceuticals |
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| US8297028B2 (en) | 2006-06-14 | 2012-10-30 | The Invention Science Fund I, Llc | Individualized pharmaceutical selection and packaging |
| EP1895012A1 (en) | 2006-08-30 | 2008-03-05 | Universitätsklinikum Freiburg | Method for inducing tumor apoptosis by increasing nitric oxide levels |
| EP2083812B1 (en) * | 2006-11-21 | 2017-04-05 | Rijksuniversiteit Groningen | Use of arginase inhibitors in the treatment of asthma and allergic rhinitis |
| EP2376072A1 (en) * | 2008-12-29 | 2011-10-19 | Tartu Ülikool (University Of Tartu) | Arginase inhibitors for the treatment of depression |
| US9387185B2 (en) * | 2009-01-09 | 2016-07-12 | Christian-Albrechts-Universität Zu Kiel | N-ω-hydroxy-L-arginine derivatives for the treatment of diseases |
| KR101900016B1 (ko) * | 2009-03-12 | 2018-09-20 | 캔서 프리벤션 앤 큐어, 리미티드 | 폐 질환의 동정, 평가, 예방 및 치료 방법과, 성별에 기초하는 질환의 동정, 평가, 예방 및 치료를 포함하는 상기 방법의 키트 |
| NZ624963A (en) | 2009-04-29 | 2016-07-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| WO2012019127A2 (en) * | 2010-08-05 | 2012-02-09 | The Regents Of The University Of Colorado | Combination yeast-based immunotherapy and arginine therapy for the treatment of myeloid-derived supressor cell-associated diseases |
| RU2464019C1 (ru) * | 2011-05-31 | 2012-10-20 | Открытое акционерное общество "Новосибхимфарм" | Композиция, обладающая эндотелиопротекторным, вазодилатирующим и ангиопротекторным эффектом |
| JP6072686B2 (ja) | 2011-07-21 | 2017-02-01 | 和光純薬工業株式会社 | 血漿中アミノ酸分析用標準液 |
| US20130116325A1 (en) * | 2011-09-02 | 2013-05-09 | Mark Herthel | Compositions and methods for treating anhidrosis |
| GB201303649D0 (en) | 2013-03-01 | 2013-04-17 | Univ Aston | Hydrogen sulphide compounds |
| US10357469B2 (en) | 2015-02-18 | 2019-07-23 | Aston University | Diagnostic assay and treatment for preeclampsia |
| CU20200106A7 (es) | 2018-06-20 | 2021-08-06 | Axcella Health Inc | Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias |
| JP2022166334A (ja) | 2019-09-19 | 2022-11-02 | 国立大学法人 東京大学 | 鎌状赤血球症の改善及び／又は予防剤 |
| CA3169994A1 (en) * | 2020-02-04 | 2021-08-12 | Horizon Therapeutics Ireland Dac | Methods for the treatment of scleroderma and related conditions |
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| US4096037A (en) * | 1976-05-24 | 1978-06-20 | Pitman-Moore, Inc. | Arginase test |
| US4507314A (en) | 1983-07-20 | 1985-03-26 | Midit, Societe Fiduciaire | Drug for treating affections provoked by a too high histamine level, of the gastroduodenal mucosa and allergic affections |
| JPS6359899A (ja) * | 1986-09-01 | 1988-03-15 | Advance Co Ltd | 癌診断方法及びキツト |
| EP0441119A3 (en) | 1990-01-09 | 1992-10-14 | Richard D. Levere | The use of l-arginine in the treatment of hypertension and other vascular disorders |
| US5354934A (en) | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
| US5891459A (en) | 1993-06-11 | 1999-04-06 | The Board Of Trustees Of The Leland Stanford Junior University | Enhancement of vascular function by modulation of endogenous nitric oxide production or activity |
| US6214876B1 (en) | 1994-07-21 | 2001-04-10 | Eli Lilly And Company | Indene-1-acetamide sPLA2 inhibitors |
| US5641800A (en) | 1994-07-21 | 1997-06-24 | Eli Lilly And Company | 1H-indole-1-functional sPLA2 inhibitors |
| JPH08333313A (ja) * | 1995-02-03 | 1996-12-17 | Omeara Pty Ltd | アミノ酸、カルニチン及びマグネシウム補充用合成物及びその合成方法 |
| US5514704A (en) | 1995-03-13 | 1996-05-07 | Eli Lilly And Company | Benzothiophenes to inhibit leukotrienes |
| US6127421A (en) | 1996-01-31 | 2000-10-03 | The Board Of Trustees Of The University Of Arkansas | In ovo use of L-arginine and salts thereof in the prevention and/or treatment of pulmonary hypertension syndrome in avians |
| JP3771644B2 (ja) * | 1996-09-17 | 2006-04-26 | 株式会社大塚製薬工場 | 末梢静脈投与用輸液 |
| JP3824716B2 (ja) * | 1996-09-17 | 2006-09-20 | 株式会社大塚製薬工場 | 中心静脈投与用輸液 |
| US6027713A (en) | 1997-03-06 | 2000-02-22 | Meri Charmyne Russell | Composition and method for the treatment of exercise induced pulmonary hemorrhage |
| WO1998058633A2 (en) | 1997-06-23 | 1998-12-30 | Queen's University At Kingston | Microdose therapy of vascular conditions by no donors |
| WO1999019295A1 (en) * | 1997-10-10 | 1999-04-22 | Trustees Of The University Of Pennsylvania | Compositions and methods for inhibiting arginase activity |
| WO1999043308A2 (en) | 1998-02-27 | 1999-09-02 | Marlene Rabinovitch | Treating pulmonary hypertension through tenascin suppression and elastase inhibition |
| US6277884B1 (en) * | 1998-06-01 | 2001-08-21 | Nitromed, Inc. | Treatment of sexual dysfunction with N-hydroxyguanidine compounds |
| US6436997B1 (en) * | 1998-06-01 | 2002-08-20 | Nitromed, Inc. | Endogenous nitric oxide synthesis under conditions of low oxygen tension |
| FR2791571B1 (fr) * | 1999-04-02 | 2002-10-04 | Sod Conseils Rech Applic | Association inhibiteur(s) de no synthase et antioxydant(s) metabolique(s) |
| US6359007B1 (en) | 1999-04-07 | 2002-03-19 | Chronorx, Llc | Clinical uses for L-arginine ascorbate and various metalloarginate complexes |
| FR2794647A1 (fr) * | 1999-06-11 | 2000-12-15 | Centre Nat Rech Scient | Compositions pharmaceutique comprenant du no ou au moins un compose capable de liberer ou d'induire la formation de no dans les cellules |
| FR2799790B1 (fr) | 1999-09-24 | 2001-11-23 | Inst Francais Du Petrole | Methode et systeme d'extraction, d'analyse et de mesure sur des constituants transportes par un fluide de forage |
| US6492550B2 (en) | 2000-02-18 | 2002-12-10 | Bristol-Myers Squibb Company | Alpha-substituted thio, -oxo trifluoromethylketones as phospholipase inhibitors |
| US6784178B2 (en) * | 2000-04-12 | 2004-08-31 | Cornell Research Foundation, Inc. | Pharmacotherapy for vascular dysfunction associated with deficient nitric oxide bioactivity |
| US6956131B2 (en) * | 2000-04-13 | 2005-10-18 | Pharmacia Corporation | 2-amino-3, 4 heptenoic compounds useful as nitric oxide synthase inhibitors |
| AU2001264729A1 (en) * | 2000-05-22 | 2001-12-03 | Nitromed, Inc. | Thromboxane inhibitors, compositions and methods of use related applications |
| DK1163904T3 (da) * | 2000-06-16 | 2006-08-14 | Matthias Dr Med Rath | Sammensætning til forebyggelse af glat muskelsygdom, der omfatter ascorbat, arginin og magnesium |
| JP2004502948A (ja) | 2000-07-06 | 2004-01-29 | ファル ダイアグノスティクス | アルギニン化合物の検出のための方法及びキット |
| NZ524869A (en) * | 2000-09-22 | 2005-06-24 | Mars Uk Ltd | Food supplement |
| US6686340B2 (en) * | 2001-06-19 | 2004-02-03 | Matthias Rath | Composition and method for prevention and treatment of health conditions caused by constriction of smooth muscle cells |
| AU2003218099A1 (en) * | 2002-03-12 | 2003-09-29 | Lsu Medical Center | Modulation of the immune response through the manipulation of arginine levels |
| ITMI20021594A1 (it) * | 2002-07-19 | 2004-01-19 | Danieli Off Mecc | Metodo e impianto per la laminazione a caldo di rotaie |
| JP4723476B2 (ja) | 2003-02-14 | 2011-07-13 | チルドレンズ ホスピタル アンド リサーチ センター アット オークランド | 上昇したアルギナーゼ状態を含む、低下した一酸化窒素バイオアベイラビリティに関連する状態の治療 |
| ATE517347T1 (de) | 2004-12-01 | 2011-08-15 | Childrens Hosp & Res Ct Oak | Diagnose von leiden in zusammenhang mit verminderter arginin-bioverfügbarkeit |
-
2004
- 2004-02-13 JP JP2006503579A patent/JP4723476B2/ja not_active Expired - Fee Related
- 2004-02-13 CA CA2833559A patent/CA2833559A1/en not_active Abandoned
- 2004-02-13 EP EP04711201A patent/EP1596854A4/en not_active Ceased
- 2004-02-13 WO PCT/US2004/004369 patent/WO2004073623A2/en not_active Ceased
- 2004-02-13 CA CA2515929A patent/CA2515929C/en not_active Expired - Fee Related
- 2004-02-13 EP EP11180824A patent/EP2397128A1/en not_active Withdrawn
- 2004-12-01 US US11/002,956 patent/US7651846B2/en not_active Expired - Lifetime
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2010
- 2010-12-06 JP JP2010271007A patent/JP2011105728A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1596854A2 (en) | 2005-11-23 |
| CA2515929A1 (en) | 2004-09-02 |
| US7651846B2 (en) | 2010-01-26 |
| JP4723476B2 (ja) | 2011-07-13 |
| WO2004073623A3 (en) | 2005-03-03 |
| EP2397128A1 (en) | 2011-12-21 |
| CA2515929C (en) | 2013-11-19 |
| WO2004073623A2 (en) | 2004-09-02 |
| WO2004073623A9 (en) | 2005-01-27 |
| JP2006518387A (ja) | 2006-08-10 |
| JP2011105728A (ja) | 2011-06-02 |
| EP1596854A4 (en) | 2007-06-06 |
| US20050158401A1 (en) | 2005-07-21 |
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| EEER | Examination request |
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