CA2818031A1 - Apparatus and method for the collection of samples of exhaled air - Google Patents
Apparatus and method for the collection of samples of exhaled air Download PDFInfo
- Publication number
- CA2818031A1 CA2818031A1 CA2818031A CA2818031A CA2818031A1 CA 2818031 A1 CA2818031 A1 CA 2818031A1 CA 2818031 A CA2818031 A CA 2818031A CA 2818031 A CA2818031 A CA 2818031A CA 2818031 A1 CA2818031 A1 CA 2818031A1
- Authority
- CA
- Canada
- Prior art keywords
- exhalation
- air
- nasal airways
- sample
- isolating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims abstract description 55
- 230000029058 respiratory gaseous exchange Effects 0.000 claims abstract description 38
- 230000008859 change Effects 0.000 claims abstract description 29
- 230000003213 activating effect Effects 0.000 claims abstract description 8
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims description 82
- 210000000214 mouth Anatomy 0.000 claims description 41
- 238000001514 detection method Methods 0.000 claims description 25
- 210000000038 chest Anatomy 0.000 claims description 19
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- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 claims description 2
- 229910002091 carbon monoxide Inorganic materials 0.000 claims description 2
- 239000013618 particulate matter Substances 0.000 claims description 2
- 239000003570 air Substances 0.000 description 186
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 30
- 229910002092 carbon dioxide Inorganic materials 0.000 description 15
- 239000001569 carbon dioxide Substances 0.000 description 15
- 239000007789 gas Substances 0.000 description 14
- 230000008961 swelling Effects 0.000 description 14
- 239000000853 adhesive Substances 0.000 description 8
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 6
- 239000001301 oxygen Substances 0.000 description 6
- 229910052760 oxygen Inorganic materials 0.000 description 6
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
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- 102000004127 Cytokines Human genes 0.000 description 2
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- 239000005041 Mylar™ Substances 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
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- 210000003238 esophagus Anatomy 0.000 description 1
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- 239000011261 inert gas Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/04—Babies, e.g. for SIDS detection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/06—Children, e.g. for attention deficit diagnosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/0813—Measurement of pulmonary parameters by tracers, e.g. radioactive tracers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
- A61B5/113—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
- A61B5/1135—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing by monitoring thoracic expansion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6814—Head
- A61B5/6819—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6814—Head
- A61B5/682—Mouth, e.g., oral cavity; tongue; Lips; Teeth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/683—Means for maintaining contact with the body
- A61B5/6832—Means for maintaining contact with the body using adhesives
- A61B5/6833—Adhesive patches
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Pulmonology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Physiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102010054397.7 | 2010-12-08 | ||
| DE102010054397A DE102010054397A1 (de) | 2010-12-08 | 2010-12-08 | Verfahren und Vorrichtung zur Gasprobensammlung |
| PCT/EP2011/072116 WO2012076614A2 (en) | 2010-12-08 | 2011-12-07 | Apparatus and method for the collection of samples of exhaled air |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2818031A1 true CA2818031A1 (en) | 2012-06-14 |
Family
ID=45495890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2818031A Abandoned CA2818031A1 (en) | 2010-12-08 | 2011-12-07 | Apparatus and method for the collection of samples of exhaled air |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10070804B2 (enExample) |
| EP (1) | EP2648614B1 (enExample) |
| JP (1) | JP2014503808A (enExample) |
| CN (1) | CN103237493A (enExample) |
| AU (1) | AU2011340511A1 (enExample) |
| BR (1) | BR112013013993A2 (enExample) |
| CA (1) | CA2818031A1 (enExample) |
| DE (1) | DE102010054397A1 (enExample) |
| WO (1) | WO2012076614A2 (enExample) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8021308B2 (en) | 2003-06-19 | 2011-09-20 | Capnia, Inc. | Breath end-tidal gas monitor |
| WO2013026902A1 (en) * | 2011-08-23 | 2013-02-28 | Aerocrine Ab | Devices and methods for generating an artificial exhalation profile |
| CN107874761A (zh) | 2011-12-21 | 2018-04-06 | 卡普尼亚公司 | 在补偿呼吸参数频率的情况下收集并分析一定体积的呼出的气体 |
| BR122016007637B1 (pt) * | 2012-04-17 | 2021-04-13 | Fisher & Paykel Healthcare Limited | Sistema de preensão de tubo |
| US20140144439A1 (en) * | 2012-11-28 | 2014-05-29 | Air Liquide Santé (International) | Dosimetric therapeutic gas delivery system for rapid dose monitoring and control |
| US20140144441A1 (en) * | 2012-11-28 | 2014-05-29 | L'Air Liquide, Société Anonyme pour I'Etude et I'Exploitation des Procédés Georges Claude | Dosimetric therapeutic gas delivery method for rapid dosimetry adjustment and optimization |
| US20140144440A1 (en) * | 2012-11-28 | 2014-05-29 | Air Liquide Santé (International) | Dosimetric therapeutic gas delivery method with feed back control for rapid dosimetry adjustment and optimization |
| US9955918B2 (en) * | 2012-12-31 | 2018-05-01 | University of Alaska Anchorage | Mouth guard for determining physiological conditions of a subject and systems and methods for using same |
| US10028679B2 (en) | 2012-12-31 | 2018-07-24 | University of Alaska Anchorage | Devices, systems, and methods for determining linear and angular accelerations of the head |
| CA2897533A1 (en) | 2013-01-08 | 2014-07-17 | Capnia, Inc. | Breath selection for analysis |
| CA2900626A1 (en) * | 2013-02-12 | 2014-08-21 | Capnia, Inc. | Sampling and storage registry device for breath gas analysis |
| US9486600B2 (en) * | 2013-06-28 | 2016-11-08 | L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude | Nasal cannula assembly with inhalation valves communicating with a deformable reservoir |
| US9492626B2 (en) * | 2013-06-28 | 2016-11-15 | L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude | Breathing assistance assemblies suitable for long term no therapy |
| US9566407B2 (en) * | 2013-06-28 | 2017-02-14 | L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude | Nasal cannula assembly with flow control passage communicating with a deformable reservoir |
| US9522248B2 (en) * | 2013-06-28 | 2016-12-20 | L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude | Breathing assistance apparatus for delivery of nitric oxide to a patient by means of a nasal cannula assembly with flow control passage |
| US9517318B2 (en) * | 2013-06-28 | 2016-12-13 | L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude | Method of delivering medical gases via a nasal cannula assembly with flow control passage communicating with a deformable reservoir |
| US9522247B2 (en) * | 2013-06-28 | 2016-12-20 | L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude | Method of treating a patient having pulmonary hypertension by long term NO therapy |
| SG11201601442UA (en) | 2013-08-30 | 2016-03-30 | Capnia Inc | Neonatal carbon dioxide measurement system |
| US20150084774A1 (en) * | 2013-09-26 | 2015-03-26 | Mark Henry Wojcik | Remote breath alcohol monitor |
| US9829480B2 (en) | 2013-09-26 | 2017-11-28 | Alcohol Monitoring Systems, Inc. | Remote breath alcohol monitor |
| CN103487489B (zh) * | 2013-10-16 | 2017-01-25 | 无锡市尚沃医疗电子股份有限公司 | 自标定呼气一氧化氮分析仪 |
| WO2016033382A1 (en) | 2014-08-27 | 2016-03-03 | Capnia, Inc. | Methods for immune globulin administration |
| EP3212084A1 (en) * | 2014-10-29 | 2017-09-06 | Koninklijke Philips N.V. | Fixation method for a nasal septum sensor for measuring medical parameters |
| CN104485104A (zh) * | 2014-12-16 | 2015-04-01 | 芜湖乐锐思信息咨询有限公司 | 智能穿戴设备 |
| US10869614B2 (en) * | 2014-12-31 | 2020-12-22 | Koninklijke Philips N.V. | System for performing histogram analysis of the time-based capnography signals and method of operation thereof |
| CN104792429A (zh) * | 2015-03-30 | 2015-07-22 | 哈尔滨医科大学 | 一种用于测量机械通气患者呼出气温度的装置 |
| US10251581B2 (en) * | 2015-04-13 | 2019-04-09 | Randolph B. Capone | Nasal airflow measuring devices and methods |
| JP6849666B2 (ja) * | 2015-09-15 | 2021-03-24 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 新生児医療を向上させる方法及び装置 |
| US11484222B2 (en) * | 2015-10-11 | 2022-11-01 | Oridion Medical 1987 Ltd. | Single infrared sensor capnography |
| US10226201B2 (en) * | 2015-10-29 | 2019-03-12 | Invoy Holdings, Llc | Flow regulation device for breath analysis and related method |
| JP6772481B2 (ja) * | 2016-02-26 | 2020-10-21 | 株式会社ジェイ・エム・エス | 口腔関連圧力測定用プローブ |
| CN106066270B (zh) * | 2016-03-15 | 2019-11-29 | 深圳市先亚生物科技有限公司 | 一种全自动呼气采集装置和方法 |
| KR101927446B1 (ko) | 2016-03-18 | 2018-12-10 | 주식회사 센시스 | 일산화탄소 측정을 위한 호기 필터 장치 |
| WO2017189546A1 (en) * | 2016-04-26 | 2017-11-02 | Endo Medical, Inc. | Breath analysis device |
| US20170347918A1 (en) * | 2016-06-02 | 2017-12-07 | Pulmostics Limited | Breath capture device |
| KR101816804B1 (ko) * | 2016-07-05 | 2018-01-10 | 한국과학기술연구원 | 호기가스 진단장치 |
| EP3484363B1 (en) * | 2016-07-13 | 2025-09-10 | Airofit A/S | Respiratory device and system for exercising and analysing respiration of a subject |
| CN106198124B (zh) * | 2016-08-24 | 2019-02-12 | 无锡市尚沃医疗电子股份有限公司 | 一种内源性气体鼻呼气采样与分析装置 |
| CN106289889B (zh) * | 2016-08-30 | 2019-05-21 | 无锡市尚沃医疗电子股份有限公司 | 一种对口与鼻呼气分子同时采样与分析装置 |
| KR101863056B1 (ko) * | 2016-09-19 | 2018-05-31 | 연암공과대학교산학협력단 | 압전소자로 자체충전이 가능한 체온계 내장형 공갈 젖꼭지 |
| EP3534777B1 (en) | 2016-11-01 | 2024-03-27 | Nihon Kohden Corporation | Apparatus to screen for and monitor cerebrovascular stenosis |
| KR102054986B1 (ko) * | 2017-01-09 | 2019-12-12 | (주)엘메카 | 환자의 호흡 측정용 기체 유량 측정 센서 구조체 |
| CN106860988B (zh) * | 2017-03-09 | 2023-05-26 | 南昌大学第二附属医院 | 一种智能调控人工鼻安全气囊控制系统 |
| CN108663238B (zh) * | 2017-04-01 | 2024-05-28 | 福建省先亚药业有限公司 | 一种呼气试验用气体样品采集袋、采集装置及采集方法 |
| DE102017209909A1 (de) * | 2017-06-13 | 2018-12-13 | Robert Bosch Gmbh | Mundstück, System und Verfahren für eine Freigabe einer Messung von Analyten in Ausatemluft |
| JP6861415B2 (ja) * | 2017-08-10 | 2021-04-21 | フィガロ技研株式会社 | 呼気検出装置 |
| CN108309358A (zh) * | 2018-01-31 | 2018-07-24 | 上海交通大学医学院附属上海儿童医学中心 | 奶嘴式检测装置 |
| CN111801048A (zh) * | 2018-02-20 | 2020-10-20 | 明尼苏达大学董事会 | 呼吸取样面罩和系统 |
| IT201800007477A1 (it) * | 2018-07-24 | 2020-01-24 | Apparecchiatura per lo stoccaggio di un campione di respiro umano e relativo procedimento di stoccaggio di un campione di respiro umano | |
| US20200038708A1 (en) * | 2018-08-01 | 2020-02-06 | Dwight Cheu | System and method for optimizing diaphragmatic breathing |
| EP3867639A1 (en) | 2018-10-19 | 2021-08-25 | Regents of the University of Minnesota | Systems and methods for detecting a brain condition |
| DE102019200322A1 (de) * | 2019-01-14 | 2020-07-16 | Robert Bosch Gmbh | Vorrichtung zur Sammlung einer gasförmigen Atemprobe eines Probanden |
| CN109932404A (zh) * | 2019-03-25 | 2019-06-25 | 上海交通大学医学院附属上海儿童医学中心 | 一种在线体液检测装置和婴儿口腔分泌物在线检测装置 |
| EP3962358A1 (en) | 2019-04-29 | 2022-03-09 | Regents of the University of Minnesota | Systems and methods for assessing and treating hemorrhage and other conditions |
| CN110179467B (zh) * | 2019-05-29 | 2023-11-14 | 中国医学科学院生物医学工程研究所 | 一种用于肺癌诊断的呼吸采样装置 |
| CA3169789A1 (en) * | 2020-02-28 | 2021-09-02 | Christopher Quentin PURVES | An apparatus and method for collecting a breath sample using a metering device along an exhaust conduit |
| DE102020123623A1 (de) * | 2020-09-10 | 2022-03-10 | Weinmann Emergency Medical Technology Gmbh + Co. Kg | Verfahren und Vorrichtung zur Messung des Gehalts zumindest eines Gases in Ausatemluft sowie Vorrichtung zur Beatmung |
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| CN113509211A (zh) * | 2021-04-21 | 2021-10-19 | 北京金科嘉信科技有限公司 | 一种兽用口腔腔内气体采集器 |
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| CN116746908B (zh) * | 2023-08-16 | 2023-10-24 | 南京诺令生物科技有限公司 | 呼出气一氧化氮检测系统及其使用方法 |
| CN120304875B (zh) * | 2025-06-19 | 2025-08-19 | 四川省畜牧科学研究院 | 一种用于牛的短期呼吸快速采集装置 |
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| CA266938A (en) | 1926-12-21 | C. Hopkins Marcus | Loud speaker | |
| AT384738B (de) * | 1985-02-20 | 1987-12-28 | Frass Michael Dr | Beatmungstubus |
| US5293875A (en) * | 1992-06-16 | 1994-03-15 | Natus Medical Incorporated | In-vivo measurement of end-tidal carbon monoxide concentration apparatus and methods |
| JPH0835963A (ja) * | 1994-07-22 | 1996-02-06 | Suzuki Motor Corp | 呼気採取分析装置 |
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| US6722367B1 (en) * | 1997-12-22 | 2004-04-20 | Hansa Medical Products, Inc. | Valved fenestrated tracheotomy tube having outer and inner cannulae |
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| US20080006267A1 (en) * | 2006-07-05 | 2008-01-10 | Joseph Cahill | Method and device for treating bruxism while sleeping |
| WO2008130429A2 (en) * | 2006-09-14 | 2008-10-30 | The Research Foundation of State Univesity of New York | Detecting nitric oxide |
| US20080275355A1 (en) * | 2007-05-04 | 2008-11-06 | Ekips Technologies, Inc. | Method For Diagnosing An Infectioin Condition |
| CN101243978B (zh) * | 2008-03-31 | 2010-08-11 | 南京星芒科技咨询有限公司 | 呼吸采样器及呼吸采样方法 |
| JP5211361B2 (ja) * | 2009-02-17 | 2013-06-12 | 日本光電工業株式会社 | 呼気導入ガイド、呼吸気濃度測定センサ、および呼吸気流量測定センサ |
| JP5575223B2 (ja) * | 2009-04-02 | 2014-08-20 | ブリーズ・テクノロジーズ・インコーポレーテッド | 非侵襲性換気システム、患者の気道閉塞を少なくするシステムおよび睡眠時無呼吸を治療するデバイス |
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| BR112013013993A2 (pt) | 2016-10-04 |
| CN103237493A (zh) | 2013-08-07 |
| US20130245483A1 (en) | 2013-09-19 |
| WO2012076614A3 (en) | 2012-09-27 |
| JP2014503808A (ja) | 2014-02-13 |
| DE102010054397A1 (de) | 2012-06-14 |
| EP2648614B1 (en) | 2019-01-16 |
| AU2011340511A1 (en) | 2013-05-30 |
| US10070804B2 (en) | 2018-09-11 |
| EP2648614A2 (en) | 2013-10-16 |
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