CA2808755C - Screwing assembly for screwing closing plugs onto syringes - Google Patents

Screwing assembly for screwing closing plugs onto syringes Download PDF

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Publication number
CA2808755C
CA2808755C CA2808755A CA2808755A CA2808755C CA 2808755 C CA2808755 C CA 2808755C CA 2808755 A CA2808755 A CA 2808755A CA 2808755 A CA2808755 A CA 2808755A CA 2808755 C CA2808755 C CA 2808755C
Authority
CA
Canada
Prior art keywords
plate
hopper
pocket
screwing
screwing assembly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2808755A
Other languages
French (fr)
Other versions
CA2808755A1 (en
Inventor
Walter Bianco
Paolo Giribona
Michele Minisini
Enrico Merlani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Omnicell Inc
Original Assignee
Aesynt Topco BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aesynt Topco BV filed Critical Aesynt Topco BV
Priority to CA2808755A priority Critical patent/CA2808755C/en
Publication of CA2808755A1 publication Critical patent/CA2808755A1/en
Application granted granted Critical
Publication of CA2808755C publication Critical patent/CA2808755C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1412Containers with closing means, e.g. caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1412Containers with closing means, e.g. caps
    • A61J1/1418Threaded type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/16Holders for containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3103Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104Caps for syringes without needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00Methods of manufacture, assembly or production
    • A61M2207/10Device therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B25HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25BTOOLS OR BENCH DEVICES NOT OTHERWISE PROVIDED FOR, FOR FASTENING, CONNECTING, DISENGAGING OR HOLDING
    • B25B23/00Details of, or accessories for, spanners, wrenches, screwdrivers
    • B25B23/14Arrangement of torque limiters or torque indicators in wrenches or screwdrivers

Abstract

A closing plug is screwed onto the threaded open end of a syringe by a screwing assembly provided with a pocket adapted to receive the closing plug from a hopper which houses in its inside a plurality of closing plugs, a support device of the syringe, and an actuating device for moving the pocket and the support device with respect to each other with a roto-translating movement about and along a longitudinal axis of the syringe so as to screw the closing plug onto the open end of the syringe itself.

Description

SCREWING ASSEMBLY FOR SCREWING CLOSING PLUGS ONTO
SYRINGES
The present invention relates to a screwing assembly for screwing closing plugs onto syringes.
In the injectable pharmaceutical product preparation, it is known to make a machine comprising at least one store for a plurality of containers (bags, syringes and bottles, in the case in point); at least one dosing station for the preparation of pharmaceutical product obtained by feeding into a syringe a pharmaceutical taken from a bottle and diluent taken from a bag; and a gripping and conveying device for transferring the containers between the store and the dosing station.
The syringe comprises a containment cylinder, a plunger engaged in sliding manner in the containment cylinder and a needle snap-locked onto an open end of the containment cylinder itself.
After having prepared the pharmaceutical product in the syringe, the needle is removed from the syringe and the open end is sealed by means of the closing plug in order to allow medical personnel to safely handle the syringe itself.
Because the closing plug is normally snap-locked on the open end of the syringe, the known machines for the preparation of pharmaceutical products of the type described above have some drawbacks mainly deriving from
2 the fact that the closing plug and the syringe are moved against each other with a relatively high coupling force, which may damage both the closing plug and the open end of the containment cylinder, thus preventing the subsequent assembly of a new needle.
Furthermore, the known machines for the preparation of pharmaceutical products of the type described above do not allow the use of threaded closing plugs and thus have a relatively low flexibility of use.
It is the object of the present invention to provide a screwing assembly for screwing closing plugs on syringes which is free from the above-described drawbacks and which is simple and cost-effective to implement.
According to the present invention, a screwing assembly for screwing closing plugs onto syringes is provided as disclosed in the appended claims.
The present invention will now be described with reference to the accompanying drawings, which illustrate a non-limitative embodiment thereof, in which:
figure 1 is a perspective diagrammatic view, with parts removed for clarity, of a preferred embodiment of the screwing assembly of the present invention;
figure 2 is a diagrammatic plan view of a detail in figure 1; and figure 3 is an exploded perspective view of the detail in figure 2.
With reference to figures 1, 2, and 3, numeral 1
3 indicates as a whole a screwing assembly for screwing closing plugs 2 of substantially quadrilateral shape onto syringes 3 of known type, each of which has a given longitudinal axis 4 and comprises a containment cylinder 5, which is provided with a externally threaded open end 6, and is slidingly engaged by a plunger 7.
In the case in point, the plugs 2 are designed so as to be absolutely tamperproof during handling of the syringes 3 containing the pharmaceutical product to be administered to patients.
The screwing assembly 1 comprises a boxed frame 8 closed on the top by a containment hopper 9 for a plurality of plugs 2 arranged within the hopper 9 with their concavities facing upwards.
The hopper 9 comprises a vibrating plate 10, which has a substantially rectangular shape, defines a support plane P for the plugs 2 inclined according to a given angle with respect to a substantially horizontal reference plane, and has an outlet hole 11, which is obtained through a lower end of the plate 10, and has a longitudinal axis 12 substantially perpendicular to the plane P itself.
The plate 10 is slidingly coupled to the frame 8 with the interposition of a shock absorber device 13 to perform rectilinear movements in a direction 14 substantially parallel to axis 12 with respect to the frame 8, and is additionally coupled in sliding manner to the frame 8 to move with respect to the frame 8 and
4 under the bias of an actuating device 15, with a reciprocating rectilinear motion in a substantially horizontal direction 16 transversal to direction 14.
Device 13 comprises, in the case in point, four elastic elements 17 mounted between frame 8 and plate 10 at the vertexes of the plate 10 itself; and the device comprises an electromagnetic actuator 18, which is fixed within the frame 8 parallel to direction 16, and has an outlet rod 19 connected to a coupling bracket 20 10 protruding downwards from the plate 10.
The hopper 9 is limited on the side by a hollow plate 21, which is fork-shaped, is fixed onto the plate 10 to define an advancement channel 22 of the plugs 2 along the plane P and towards the hole 11, and is shaped 15 so as to divide the channel 22 into a lower substantially rectilinear outlet section 22a connected to the hole 11 and an upper inlet section 22b converging towards section 22a.
Channel 22 cooperates with a first stop device 23 comprising an actuating cylinder 24, which is mounted inside the plate 21 parallel to direction 16, and has an output rod 25 mobile between a rest position, in which the rod 25 is substantially contained in the plate 21, and an operating position, in which the rod 25 protrudes into the section 22a to prevent the plugs 2 from reaching the inside of the section 22a itself.
The channel 22 further cooperates with a second stop device 26, comprising an actuating cylinder 27, . .
which is mounted inside the plate 21 parallel to direction 16, and has an output rod 28 mobile between a rest position, in which the rod 28 is substantially contained in the plate 21, and an operating position, in
5 which the rod 28 protrudes into the section 22a downstream of the rod 25 to prevent the plugs 2 from reaching the hole 11.
With regards to this, it is worth specifying that the movement of the rods 25 and 28 in their operating positions defines a compartment adapted to accommodate a single plug 2 therein.
The screwing assembly 1 further comprises a support device 29 of a syringe 3, e.g. a robotized arm, adapted to keep the syringe 3 in position coaxial to the axis 12, and a support device 30 adapted to receive the plug 2 fed each time through the hole 11.
The device 30 comprises a pocket 31, which is mounted inside the frame 8, under the plate 10, and in position facing the hole 11, is limited by a bottom wall 32, which has a quadrilateral shape substantially corresponding to the shape of the plugs 2, and which extends perpendicular to direction 14, and is further limited by a quadrilateral side wall 33, which extends about axis 12, and is inclined according to an angle other than 90 with respect to the wall 32 itself.
The pocket 31 is mounted on the free end of the outlet shaft 34 of an electric motor 35, which is mounted within the frame 8 parallel to direction 14, is six
6 fixed to the hopper 9 under the plate 10, is adapted to move the pocket 31, with respect to the plate 10 itself, about axis 12, and is torque-controlled so as to allow the correct screwing of the plugs 2 onto the respective syringes 3.
The shape of the pocket 31 and of the lower outlet section 22a of the channel 22 allows the plugs 2 to drop through the hole 11 so as to be aligned with, and correctly inserted in the pocket 31 itself during the rotation about the axis 12.
The operation of screwing assembly I will now be described with reference to figures 1, 2 and 3 starting from an instant in which:
the syringe 3 is moved by the device 29 to a position coaxial to axis 12;
the stop devices 23, 26 are arranged in their operating positions; and the outlet section 22a of the channel 22 is empty.
Device 23 is firstly moved to its rest position to allow a plug 2 to drop into the section 22a and is then moved again to its operating position to prevent other plugs 2 from dropping into the section 22a itself.
The device 26 is thus moved to the rest position thereof to allow the considered plug 2 to reach the hole 11 and fall into the pocket 31.
At this point, the syringe 3 is lowered by the device 29 so as to allow the open end 6 of the syringe 3 to engage the plug 2 and to move the assembly defined by
7 the hopper 9 and by the pocket 31 against the bias of the elastic elements 17 of the shock absorbers device 13.
Finally, the pocket 31 and thus the plug 2 are moved about the axis 12 by the actuation of the electric motor 35 and along the axis 12 by the bias of the elastic element 17 of the shock absorber device 13. In other words, the pocket 31 and the plug 2 are moved with roto-translating movement about and along the mentioned axis 12 in order to screw the plug 2 onto the open end 6 of the syringe 3.
With regards to the above, it is worth noting that the pharmaceutical product contained in the syringe 3 does not exit from the end 6 due to the surface tension and the capillarity of the cylinder 5 at the open end 6 itself.

Claims (10)

THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE PROPERTY OR
PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. Screwing assembly for screwing closing plugs onto syringes, each syringe presenting a longitudinal axis and comprising a cylinder provided with a threaded open end and a plunger engaged in a sliding manner in the cylinder itself; the screwing assembly being characterized in that it includes: a fixed support frame closed on a top end by a hopper, the hopper housing in its inside a plurality of closing plugs, the hopper including a plate having an outlet for the closing plugs from the hopper itself; a pocket mounted on a bottom surface of the plate, positioned under the plate, and arranged inside the fixed support frame, the pocket suited to receive and hold the closing plug fed each time through said outlet; a support device for supporting the syringe; actuating means for moving the pocket and the support device with respect to one another with a roto-translating movement around and along said longitudinal axis, so as to screw the closing plug onto said open end; and a shock absorber device positioned under the plate and interposed between the plate and the support frame, so as to allow the pocket to move with respect to the syringe parallel to said longitudinal axis while the pocket remains positioned under the plate, and while the closing plug is being screwed onto the open end of the syringe itself while the pocket remains positioned under the plate.
2. Screwing assembly according to claim 1 and comprising, furthermore, a first stop device, which is mobile inside the hopper from and to an operating position, in which the first stop device prevents a first closing plug from reaching said outlet.
3. Screwing assembly according to claim 2 and comprising, furthermore, a second stop device, which is arranged behind the first stop device, and is mobile inside the hopper from and to an operating position, in which the second stop device is arranged so as to separate the first closing plug from the remaining closing plugs contained in the hopper.
4. Screwing assembly according to claim 1, wherein the plate comprises a vibrating plate defining a support plane, which is inclined with respect to a horizontal reference plane.
5. Screwing assembly according to claim 4, wherein the hopper is delimited by a lateral wall defining a conveying channel of the closing plugs along the vibrating plate; the conveying channel comprising an outlet section connected to said outlet and an inlet section converging towards the outlet section itself.
6. Screwing assembly according to claim 5 and comprising, furthermore, a first stop device, which is mobile inside the hopper from and to an operating position, in which the first stop device prevents the closing plugs from being transferred from the outlet section to said outlet, and a second stop device, which is mobile inside the hopper from and to an operating position, in which the second stop device prevents the closing plugs from being transferred from the inlet section to the outlet section.
7. Screwing assembly according to claim 1 and comprising, furthermore, an electric motor for moving the pocket around said longitudinal axis.
8. Screwing assembly according to claim 1, wherein the pocket is delimited by a bottom wall, which is perpendicular to said longitudinal axis, and by a lateral wall, which is inclined with respect to the bottom wall itself at an angle different from 90°.
9. Screwing assembly according to claim 8, wherein the lateral wall of the pocket presents a quadrilateral shape.
10. Screwing assembly according to claim 1, wherein the plate includes four vertices; and wherein the shock absorber device includes four elastic elements, each elastic element mounted between the support frame and the plate at a respective vertex of the plate.
CA2808755A 2013-03-06 2013-03-06 Screwing assembly for screwing closing plugs onto syringes Active CA2808755C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2808755A CA2808755C (en) 2013-03-06 2013-03-06 Screwing assembly for screwing closing plugs onto syringes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA2808755A CA2808755C (en) 2013-03-06 2013-03-06 Screwing assembly for screwing closing plugs onto syringes

Publications (2)

Publication Number Publication Date
CA2808755A1 CA2808755A1 (en) 2014-09-06
CA2808755C true CA2808755C (en) 2019-10-29

Family

ID=51730168

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2808755A Active CA2808755C (en) 2013-03-06 2013-03-06 Screwing assembly for screwing closing plugs onto syringes

Country Status (1)

Country Link
CA (1) CA2808755C (en)

Also Published As

Publication number Publication date
CA2808755A1 (en) 2014-09-06

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Effective date: 20180302