CA2790653C - Recombinant attenuated parvovirus - Google Patents

Recombinant attenuated parvovirus Download PDF

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Publication number
CA2790653C
CA2790653C CA2790653A CA2790653A CA2790653C CA 2790653 C CA2790653 C CA 2790653C CA 2790653 A CA2790653 A CA 2790653A CA 2790653 A CA2790653 A CA 2790653A CA 2790653 C CA2790653 C CA 2790653C
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CA
Canada
Prior art keywords
parvovirus
capsid protein
dna
recombinant
attenuated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2790653A
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English (en)
French (fr)
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CA2790653A1 (en
Inventor
Norman Spibey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intervet International BV
Original Assignee
Intervet International BV
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Filing date
Publication date
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Publication of CA2790653A1 publication Critical patent/CA2790653A1/en
Application granted granted Critical
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Active legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/23—Parvoviridae, e.g. feline panleukopenia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14311—Parvovirus, e.g. minute virus of mice
    • C12N2750/14334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14311—Parvovirus, e.g. minute virus of mice
    • C12N2750/14361—Methods of inactivation or attenuation
    • C12N2750/14362—Methods of inactivation or attenuation by genetic engineering

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CA2790653A 2010-03-05 2011-03-03 Recombinant attenuated parvovirus Active CA2790653C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US31103210P 2010-03-05 2010-03-05
EP10155646 2010-03-05
EP10155646.2 2010-03-05
US61/311,032 2010-03-05
PCT/EP2011/053164 WO2011107534A1 (en) 2010-03-05 2011-03-03 Recombinant attenuated parvovirus

Publications (2)

Publication Number Publication Date
CA2790653A1 CA2790653A1 (en) 2011-09-09
CA2790653C true CA2790653C (en) 2019-02-19

Family

ID=42562704

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2790653A Active CA2790653C (en) 2010-03-05 2011-03-03 Recombinant attenuated parvovirus

Country Status (10)

Country Link
US (1) US9234182B2 (cg-RX-API-DMAC7.html)
EP (1) EP2542260B1 (cg-RX-API-DMAC7.html)
JP (3) JP6200155B2 (cg-RX-API-DMAC7.html)
CN (1) CN102791288B (cg-RX-API-DMAC7.html)
AU (1) AU2011222910B2 (cg-RX-API-DMAC7.html)
CA (1) CA2790653C (cg-RX-API-DMAC7.html)
DK (1) DK2542260T3 (cg-RX-API-DMAC7.html)
ES (1) ES2566033T3 (cg-RX-API-DMAC7.html)
RU (1) RU2527157C2 (cg-RX-API-DMAC7.html)
WO (1) WO2011107534A1 (cg-RX-API-DMAC7.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9234182B2 (en) * 2010-03-05 2016-01-12 Intervet Inc. Recombinant attenuated parvovirus
US9314519B2 (en) 2012-08-21 2016-04-19 Intervet Inc. Liquid stable virus vaccines
US20140234354A1 (en) * 2013-02-15 2014-08-21 Boehringer Ingelheim Vetmedica, Inc. Porcine parvovirus 5b, methods of use and vaccine
AR097762A1 (es) 2013-09-27 2016-04-13 Intervet Int Bv Formulaciones secas de vacunas que son estables a temperatura ambiente
CN105263953B (zh) * 2014-01-15 2020-01-07 勃林格殷格翰动物保健美国有限公司 猪细小病毒5a、使用方法及疫苗
BR112016023787A2 (pt) 2014-04-17 2017-10-17 Intervet Int Bv vírus isolado, cultura de células, fragmento de dna, proteína do capsídeo, gene ns1, vacina para combater parvovírus suíno associado com hbs em suínos, anticorpo ou antissoro, método para a preparação de uma vacina, e, kits de teste diagnóstico para a detecção de anticorpos reativos com um vírus e de um vírus
KR102664662B1 (ko) 2016-11-03 2024-05-14 베링거잉겔하임베트메디카게엠베하 돼지 파보바이러스 및 돼지 생식기 및 호흡기 증후군 바이러스에 대한 백신 및 이의 제조 방법
TWI781962B (zh) 2016-11-03 2022-11-01 德商百靈佳殷格翰維美迪加股份有限公司 抗豬小病毒疫苗
WO2022096472A1 (en) 2020-11-04 2022-05-12 Intervet International B.V. Canine parvovirus
CN114957406B (zh) * 2022-05-26 2024-02-02 吉林大学 一种犬细小病毒的三价抗原和三价病毒样颗粒以及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8502399D0 (en) * 1985-01-31 1985-03-06 Akzo Nv Canine parvovirus vaccines
JP2002538770A (ja) * 1998-11-10 2002-11-19 ユニバーシティ オブ ノース カロライナ アット チャペル ヒル ウイルスベクターとその製造及び投与の方法
EP2292250A1 (en) * 2005-07-28 2011-03-09 Pfizer Products Inc. Methods of vaccine administration, new feline caliciviruses, and treatments for immunizing animals against feline parvovirus and feline herpes virus
EP2170383A4 (en) * 2007-06-14 2012-12-26 Univ Oklahoma State GENETIC VARIANTS OF DOG PARVOVIRUS CONTAINING VACCINES
US9234182B2 (en) * 2010-03-05 2016-01-12 Intervet Inc. Recombinant attenuated parvovirus

Also Published As

Publication number Publication date
US20120328652A1 (en) 2012-12-27
CA2790653A1 (en) 2011-09-09
DK2542260T3 (en) 2016-06-06
JP6346143B2 (ja) 2018-06-20
US9234182B2 (en) 2016-01-12
JP2018134088A (ja) 2018-08-30
CN102791288A (zh) 2012-11-21
BR112012021650A2 (pt) 2017-02-21
ES2566033T3 (es) 2016-04-08
AU2011222910B2 (en) 2014-09-18
JP6200155B2 (ja) 2017-09-20
EP2542260A1 (en) 2013-01-09
RU2012142309A (ru) 2014-04-10
EP2542260B1 (en) 2016-03-02
CN102791288B (zh) 2015-02-18
RU2527157C2 (ru) 2014-08-27
AU2011222910A1 (en) 2012-09-27
WO2011107534A1 (en) 2011-09-09
JP2016047053A (ja) 2016-04-07
JP2013520977A (ja) 2013-06-10

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