CA2787978A1 - Interferon-beta for anti-virus therapy for respiratory diseases - Google Patents

Interferon-beta for anti-virus therapy for respiratory diseases Download PDF

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Publication number
CA2787978A1
CA2787978A1 CA2787978A CA2787978A CA2787978A1 CA 2787978 A1 CA2787978 A1 CA 2787978A1 CA 2787978 A CA2787978 A CA 2787978A CA 2787978 A CA2787978 A CA 2787978A CA 2787978 A1 CA2787978 A1 CA 2787978A1
Authority
CA
Canada
Prior art keywords
cells
ifn
infection
agent
asthmatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2787978A
Other languages
English (en)
French (fr)
Inventor
Donna Elizabeth Davies
Stephen Holgate
Peter Alexander Blanch Wark
Sebastian L. Johnston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southampton
Original Assignee
University of Southampton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Southampton filed Critical University of Southampton
Publication of CA2787978A1 publication Critical patent/CA2787978A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CA2787978A 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases Abandoned CA2787978A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0405634.7A GB0405634D0 (en) 2004-03-12 2004-03-12 Anti-virus therapy for respiratory diseases
GB0405634.7 2004-03-12
CA2558212A CA2558212C (en) 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2558212A Division CA2558212C (en) 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases

Publications (1)

Publication Number Publication Date
CA2787978A1 true CA2787978A1 (en) 2005-09-22

Family

ID=32117582

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2787978A Abandoned CA2787978A1 (en) 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases
CA2558212A Expired - Lifetime CA2558212C (en) 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2558212A Expired - Lifetime CA2558212C (en) 2004-03-12 2005-03-07 Interferon-beta for anti-virus therapy for respiratory diseases

Country Status (12)

Country Link
US (3) US7569216B2 (enExample)
EP (2) EP2206512A3 (enExample)
JP (2) JP4807526B2 (enExample)
AT (1) ATE466591T1 (enExample)
CA (2) CA2787978A1 (enExample)
DE (1) DE602005021078D1 (enExample)
DK (1) DK1734987T3 (enExample)
ES (1) ES2343732T3 (enExample)
GB (1) GB0405634D0 (enExample)
PL (1) PL1734987T3 (enExample)
PT (1) PT1734987E (enExample)
WO (1) WO2005087253A2 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0405634D0 (en) 2004-03-12 2004-04-21 Univ Southampton Anti-virus therapy for respiratory diseases
US8318423B2 (en) * 2004-07-06 2012-11-27 Focus Diagnostics, Inc. Methods and compositions for detecting rhinoviruses
WO2007029041A2 (en) * 2005-09-09 2007-03-15 Imperial Innovations Limited Interferon lambda therapy for treatment of respiratory diseases
WO2007035180A1 (en) * 2005-09-20 2007-03-29 New York University Method of treating pulmonary disease with interferons
DE102006022877B4 (de) 2006-05-15 2009-01-29 Sartorius Stedim Biotech Gmbh Verfahren zur Bestimmung der Viabilität von Zellen in Zellkulturen
US7871603B2 (en) 2007-05-18 2011-01-18 Synairgen Research Limited Interferon-beta and/or lambda for use in treating rhinovirus infection in the elderly
GB0713402D0 (en) * 2007-07-11 2007-08-22 Cardiff & Vale Nhs Trust A method of diagnosing a condition using a neural network
AU2008334605B2 (en) * 2007-12-13 2013-07-18 Glaxo Group Limited Polypeptides, antibody variable domains & antagonists
EP2373329A4 (en) * 2008-12-19 2012-07-04 Univ California USE OF INGREDIENTS OF THE EPIDERMAL GROWTH FACTOR IN THE TREATMENT OF VIRUS INFECTIONS
CA2782512A1 (en) 2009-12-02 2011-06-09 Neetour Medical Ltd. Hemodynamics-based monitoring and evaluation of a respiratory condition
EP2544705B1 (en) * 2010-03-12 2016-08-31 Synairgen Research Limited Interferon beta for use in the treatment of lower respiratory tract illness caused by influenza
CN105477640B (zh) 2010-09-22 2019-09-17 因纳瓦克私人有限公司 新型免疫刺激方法
CN109293782A (zh) 2014-01-08 2019-02-01 德益阳光生物技术(北京)有限责任公司 融合多肽及使用方法
WO2019023196A1 (en) * 2017-07-24 2019-01-31 Novavax, Inc. METHODS AND COMPOSITIONS FOR TREATING RESPIRATORY DISEASE
CN111491943A (zh) 2017-12-21 2020-08-04 艾娜医疗私人有限公司 优化的化合物
EP3923975A4 (en) * 2019-02-13 2023-04-19 University of Florida Research Foundation, Inc. TARGETING A LUNG-RESIDENT TNFR2+ CDC2 (R2D2) SUBPOPULATION TO TREAT ASTHMA
CN121045535A (zh) 2019-06-26 2025-12-02 艾娜呼吸私人有限公司 新型分子
JP2023535710A (ja) 2020-07-20 2023-08-21 シナーゲン リサーチ リミテッド SARS-CoV-2感染患者におけるアウトカムを改善するための吸入インターフェロン-ベータ
GB202014114D0 (en) * 2020-09-08 2020-10-21 Synairgen Res Ltd Use of inhaled interferon-beta to treat virus-induced exacerbations in copd patients undergoing treatment with a systemic corticosteroid
MX2023005302A (es) * 2020-11-04 2023-05-25 Ethris Gmbh Uso de arnm de ifn-lambda para el tratamiento de infecciones viricas.
WO2022154542A1 (ko) * 2021-01-13 2022-07-21 에이비온 주식회사 잠재적인 호흡기바이러스 감염 개체에 인터페론-베타를 투여하는 것을 포함하는 호흡기바이러스에 대한 예방적 투여 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596260B1 (en) * 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
JPH10500672A (ja) * 1994-05-18 1998-01-20 インヘイル セラピューティック システムズ,インコーポレイティド インターフェロンの乾燥粉末製剤に関する方法及び組成物
US6030609A (en) 1995-05-19 2000-02-29 Case Western Reserve University Method and composition for treating paramyxovirus
US20010031253A1 (en) * 1996-07-24 2001-10-18 Gruenberg Micheal L. Autologous immune cell therapy: cell compositions, methods and applications to treatment of human disease
AU780270B2 (en) * 2000-02-23 2005-03-10 Association Francaise Contre Les Myopathies Treatment of immune diseases
GB2362884A (en) 2000-05-30 2001-12-05 Isis Innovation Extended duration of airway gene therapy
EP1334128A2 (en) 2000-11-02 2003-08-13 Maxygen Aps New multimeric interferon beta polypeptides
US20030091544A1 (en) * 2001-03-13 2003-05-15 Vical Incorporated Interferon-Beta polynucleotide therapy for autoimmune and inflammatory diseases
AU2003215136A1 (en) 2002-02-08 2003-09-02 University Of Medicine And Dentistry Of New Jersey Ifn-a/b-independent mechanism of antiviral protection
US20040037809A1 (en) * 2002-06-28 2004-02-26 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of interferon beta
CA2503305A1 (en) 2002-10-23 2004-05-06 Zymogenetics, Inc. Methods for treating viral infection using il-28 and il-29
CN1910200A (zh) 2003-08-07 2007-02-07 津莫吉尼蒂克斯公司 Il-28和il-29的均一化制剂
GB0405634D0 (en) 2004-03-12 2004-04-21 Univ Southampton Anti-virus therapy for respiratory diseases
AU2005231476B2 (en) 2004-04-02 2011-09-01 Zymogenetics, Inc. Il-28 and il-29 cysteine mutants for treating viral infection

Also Published As

Publication number Publication date
ES2343732T3 (es) 2010-08-09
EP1734987A2 (en) 2006-12-27
US20070134763A1 (en) 2007-06-14
US20130209399A1 (en) 2013-08-15
JP4807526B2 (ja) 2011-11-02
JP2007528890A (ja) 2007-10-18
EP2206512A2 (en) 2010-07-14
CA2558212C (en) 2012-11-27
JP2011144201A (ja) 2011-07-28
US7569216B2 (en) 2009-08-04
US8273342B2 (en) 2012-09-25
PL1734987T3 (pl) 2010-10-29
EP1734987B1 (en) 2010-05-05
DE602005021078D1 (de) 2010-06-17
DK1734987T3 (da) 2010-08-30
US20090257980A1 (en) 2009-10-15
CA2558212A1 (en) 2005-09-22
GB0405634D0 (en) 2004-04-21
HK1097181A1 (en) 2007-06-22
US9089535B2 (en) 2015-07-28
WO2005087253A3 (en) 2005-11-24
WO2005087253A2 (en) 2005-09-22
PT1734987E (pt) 2010-07-06
ATE466591T1 (de) 2010-05-15
EP2206512A3 (en) 2013-01-09

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140219

FZDE Discontinued

Effective date: 20151222