CA2784519A1 - A method for controlling culture parameters in a bioreactor - Google Patents

A method for controlling culture parameters in a bioreactor Download PDF

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Publication number
CA2784519A1
CA2784519A1 CA2784519A CA2784519A CA2784519A1 CA 2784519 A1 CA2784519 A1 CA 2784519A1 CA 2784519 A CA2784519 A CA 2784519A CA 2784519 A CA2784519 A CA 2784519A CA 2784519 A1 CA2784519 A1 CA 2784519A1
Authority
CA
Canada
Prior art keywords
bioreactor
information
bag
control unit
dependence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2784519A
Other languages
English (en)
French (fr)
Inventor
Klaus Gebauer
Eva Lindskog
Lars Magnusson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
Original Assignee
GE Healthcare Bio Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44196030&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2784519(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by GE Healthcare Bio Sciences Corp filed Critical GE Healthcare Bio Sciences Corp
Publication of CA2784519A1 publication Critical patent/CA2784519A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Computer Hardware Design (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2784519A 2009-12-22 2010-12-20 A method for controlling culture parameters in a bioreactor Abandoned CA2784519A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0951006 2009-12-22
SE0951006-6 2009-12-22
PCT/SE2010/051425 WO2011078773A1 (en) 2009-12-22 2010-12-20 A method for controlling culture parameters in a bioreactor

Publications (1)

Publication Number Publication Date
CA2784519A1 true CA2784519A1 (en) 2011-06-30

Family

ID=44196030

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2784519A Abandoned CA2784519A1 (en) 2009-12-22 2010-12-20 A method for controlling culture parameters in a bioreactor

Country Status (7)

Country Link
US (1) US20120258441A1 (OSRAM)
EP (1) EP2516682B1 (OSRAM)
JP (1) JP6169847B2 (OSRAM)
CN (1) CN102656282B (OSRAM)
CA (1) CA2784519A1 (OSRAM)
IN (1) IN2012DN05207A (OSRAM)
WO (1) WO2011078773A1 (OSRAM)

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JPWO2014033889A1 (ja) * 2012-08-31 2016-08-08 株式会社日立製作所 自動培養装置及び自動培養方法
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WO2015142405A1 (en) 2014-03-21 2015-09-24 Life Technologies Corporation Gas filter systems for fluid processing systems
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US9617566B2 (en) * 2014-07-11 2017-04-11 Lanzatech New Zealand Limited Control of bioreactor processes
US9457306B2 (en) 2014-10-07 2016-10-04 Life Technologies Corporation Regulated vacuum off-gassing of gas filter for fluid processing system and related methods
ES2820771T3 (es) * 2014-10-23 2021-04-22 Cytiva Sweden Ab Sistema de biorreactor
WO2016124505A1 (en) * 2015-02-05 2016-08-11 General Electric Company Bioreactor system for cell cultivation
JP6884137B2 (ja) 2015-08-25 2021-06-09 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー バイオマニュファクチャリング装置における、およびバイオマニュファクチャリング装置に関連する改良
EP3341468A1 (en) * 2015-08-25 2018-07-04 General Electric Company Improvements in and relating to biomanufacturing apparatus
CN108138117B (zh) * 2015-08-25 2022-03-15 环球生命科技咨询美国有限责任公司 在生物制造设备中和涉及其的改进
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US9920292B2 (en) * 2015-08-31 2018-03-20 General Electric Company System and method for initiating a cell culture
CN112403668B (zh) 2015-12-29 2023-06-27 生命科技股份有限公司 具有部分分割分隔区的柔性生物处理容器
CN109312291A (zh) 2016-06-24 2019-02-05 隆萨有限公司 可变直径生物反应器
JP6207708B2 (ja) * 2016-10-18 2017-10-04 株式会社日立製作所 自動培養装置、及び細胞培養方法
CN109863240A (zh) * 2016-10-31 2019-06-07 通用电气公司 生物反应器组件
US12110481B2 (en) 2017-04-28 2024-10-08 Cytiva Sweden Ab Method and system for creating reconfigurable bio-processing workflows
EP3616301B1 (en) 2017-04-28 2022-11-09 Cytiva Sweden AB System and method for wirelessly powering a sensor in a bio-processing environment
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109890951A (zh) * 2016-10-28 2019-06-14 通用电气公司 生物反应器托盘
CN109890951B (zh) * 2016-10-28 2022-08-02 环球生命科技咨询美国有限责任公司 生物反应器托盘

Also Published As

Publication number Publication date
CN102656282B (zh) 2015-09-02
JP6169847B2 (ja) 2017-07-26
US20120258441A1 (en) 2012-10-11
EP2516682B1 (en) 2020-02-26
CN102656282A (zh) 2012-09-05
WO2011078773A1 (en) 2011-06-30
JP2013514804A (ja) 2013-05-02
EP2516682A1 (en) 2012-10-31
EP2516682A4 (en) 2016-07-13
IN2012DN05207A (OSRAM) 2015-10-23

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20141222