CA2783107C - Malaria vaccines based on apicomplexan ferlins, ferlin-like proteins and other c2-domain containing proteins - Google Patents

Malaria vaccines based on apicomplexan ferlins, ferlin-like proteins and other c2-domain containing proteins Download PDF

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Publication number
CA2783107C
CA2783107C CA2783107A CA2783107A CA2783107C CA 2783107 C CA2783107 C CA 2783107C CA 2783107 A CA2783107 A CA 2783107A CA 2783107 A CA2783107 A CA 2783107A CA 2783107 C CA2783107 C CA 2783107C
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CA
Canada
Prior art keywords
seq
protein
epitope
ferlin
apicomplexan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2783107A
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English (en)
French (fr)
Other versions
CA2783107A1 (en
Inventor
Ann-Kristin Mueller
Eva Morath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaet Heidelberg
Original Assignee
Universitaet Heidelberg
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Publication date
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Publication of CA2783107A1 publication Critical patent/CA2783107A1/en
Application granted granted Critical
Publication of CA2783107C publication Critical patent/CA2783107C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6075Viral proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2783107A 2009-12-05 2010-12-06 Malaria vaccines based on apicomplexan ferlins, ferlin-like proteins and other c2-domain containing proteins Expired - Fee Related CA2783107C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26702609P 2009-12-05 2009-12-05
US61/267,026 2009-12-05
PCT/EP2010/007399 WO2011066995A1 (en) 2009-12-05 2010-12-06 Malaria vaccines based on apicomplexan ferlins, ferlin-like proteins and other c2-domain containing proteins

Publications (2)

Publication Number Publication Date
CA2783107A1 CA2783107A1 (en) 2011-06-09
CA2783107C true CA2783107C (en) 2018-08-07

Family

ID=43499977

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2783107A Expired - Fee Related CA2783107C (en) 2009-12-05 2010-12-06 Malaria vaccines based on apicomplexan ferlins, ferlin-like proteins and other c2-domain containing proteins

Country Status (8)

Country Link
US (1) US8968750B2 (cg-RX-API-DMAC7.html)
EP (1) EP2507259B1 (cg-RX-API-DMAC7.html)
JP (1) JP2013512866A (cg-RX-API-DMAC7.html)
CN (1) CN102781958B (cg-RX-API-DMAC7.html)
BR (1) BR112012013581A8 (cg-RX-API-DMAC7.html)
CA (1) CA2783107C (cg-RX-API-DMAC7.html)
MX (1) MX2012006458A (cg-RX-API-DMAC7.html)
WO (1) WO2011066995A1 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012076157A2 (en) 2010-12-06 2012-06-14 Ruprecht-Karls-Universität Heidelberg Malaria vaccines based on pre-erythrocytic antigens from p. falciparum
ES2847930T3 (es) 2013-01-07 2021-08-04 Mucosal Vaccine Tech Llc Vacunas terapéuticas para el tratamiento de las infecciones por el virus del herpes simple de tipo 2
TWI790593B (zh) 2014-08-19 2023-01-21 美商默沙東有限責任公司 抗tigit抗體
CN108290936B (zh) * 2015-08-14 2022-07-12 默沙东公司 抗tigit抗体
JP2017210441A (ja) * 2016-05-26 2017-11-30 国立大学法人大阪大学 マラリアワクチン

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518528A (en) * 1983-05-19 1985-05-21 Rasnick David W α Amino fluoro ketones
US5198334A (en) * 1989-07-21 1993-03-30 Terumo Corporation Protection of natural killer cell cytolytic activity in peripheral blood mononuclear cells
GB9406492D0 (en) 1994-03-31 1994-05-25 Isis Innovation Malaria peptides
JP2001509813A (ja) * 1997-01-21 2001-07-24 ニューヨーク ユニヴァーシティ 抗マラリアワクチン用ユニバーサルt細胞エピトープ
US20030077653A1 (en) * 2000-04-20 2003-04-24 The University Of Georgia Research Foundation, Inc. Method for the identification of active site protease inactivators
US7811575B2 (en) * 2001-04-10 2010-10-12 Agensys, Inc. Nucleic acids and corresponding proteins entitled 158P3D2 useful in treatment and detection of cancer
GB0210128D0 (en) * 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
CA2409897A1 (en) * 2002-10-25 2004-04-25 Institut Pasteur Plasmodium falciparum virulence factor var o
US7198791B2 (en) * 2003-03-03 2007-04-03 Pluschke, Gerd Et Al. Compositions and methods for the generation of protective immune responses against malaria
CA2536819A1 (en) * 2003-08-26 2005-03-03 The Council Of The Queensland Institute Of Medical Research Immunogenic agent and pharmaceutical composition for use against homologous and heterologous pathogens including plasmodium spp
WO2005063804A1 (en) * 2003-12-30 2005-07-14 Københavns Universitet Panum Compounds useful in the diagnosis and treatment of malaria
US7951782B2 (en) * 2005-09-29 2011-05-31 Maruha Nichiro Seafoods, Inc Composition effective to prevent or treat adult disease
GB0601059D0 (en) * 2006-01-19 2006-03-01 Univ Durham Target
WO2009082440A2 (en) * 2007-12-18 2009-07-02 Vaxinnate Corporation Compositions of toll-like receptor agonists and malaria antigens and methods of use
US8343498B2 (en) * 2008-10-12 2013-01-01 Massachusetts Institute Of Technology Adjuvant incorporation in immunonanotherapeutics
US8277812B2 (en) * 2008-10-12 2012-10-02 Massachusetts Institute Of Technology Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
US8343497B2 (en) * 2008-10-12 2013-01-01 The Brigham And Women's Hospital, Inc. Targeting of antigen presenting cells with immunonanotherapeutics
WO2011085070A2 (en) * 2010-01-06 2011-07-14 Virginia Tech Intellectual Properties, Inc. Methods and compositions to improve the health of plants, animals and microbes by manipulating protein entry into symbionts and their hosts
WO2012076157A2 (en) * 2010-12-06 2012-06-14 Ruprecht-Karls-Universität Heidelberg Malaria vaccines based on pre-erythrocytic antigens from p. falciparum

Also Published As

Publication number Publication date
EP2507259B1 (en) 2016-08-24
BR112012013581A8 (pt) 2017-12-26
CN102781958B (zh) 2017-07-11
US8968750B2 (en) 2015-03-03
MX2012006458A (es) 2012-09-07
JP2013512866A (ja) 2013-04-18
WO2011066995A1 (en) 2011-06-09
BR112012013581A2 (pt) 2017-01-10
CN102781958A (zh) 2012-11-14
CA2783107A1 (en) 2011-06-09
US20120308598A1 (en) 2012-12-06
EP2507259A1 (en) 2012-10-10

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Legal Events

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EEER Examination request

Effective date: 20151117

MKLA Lapsed

Effective date: 20210831

MKLA Lapsed

Effective date: 20191206