CA2781313C - Enhanced eductor design - Google Patents
Enhanced eductor design Download PDFInfo
- Publication number
- CA2781313C CA2781313C CA2781313A CA2781313A CA2781313C CA 2781313 C CA2781313 C CA 2781313C CA 2781313 A CA2781313 A CA 2781313A CA 2781313 A CA2781313 A CA 2781313A CA 2781313 C CA2781313 C CA 2781313C
- Authority
- CA
- Canada
- Prior art keywords
- eductor
- modification member
- constriction zone
- siphon
- outlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000013461 design Methods 0.000 title description 15
- 230000004048 modification Effects 0.000 claims description 125
- 238000012986 modification Methods 0.000 claims description 125
- 239000003814 drug Substances 0.000 claims description 43
- 239000012530 fluid Substances 0.000 claims description 37
- 229940079593 drug Drugs 0.000 claims description 28
- 230000003434 inspiratory effect Effects 0.000 claims description 23
- 239000000443 aerosol Substances 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 16
- 238000009472 formulation Methods 0.000 claims description 14
- 230000007423 decrease Effects 0.000 claims description 9
- 210000004072 lung Anatomy 0.000 claims description 8
- 230000009467 reduction Effects 0.000 claims description 7
- 239000002245 particle Substances 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 5
- 230000004913 activation Effects 0.000 claims 1
- 230000007246 mechanism Effects 0.000 abstract description 10
- 229940071648 metered dose inhaler Drugs 0.000 description 14
- 238000000034 method Methods 0.000 description 11
- 238000012360 testing method Methods 0.000 description 8
- 230000008901 benefit Effects 0.000 description 7
- 238000001746 injection moulding Methods 0.000 description 7
- GDOPTJXRTPNYNR-UHFFFAOYSA-N methyl-cyclopentane Natural products CC1CCCC1 GDOPTJXRTPNYNR-UHFFFAOYSA-N 0.000 description 6
- 238000003260 vortexing Methods 0.000 description 6
- 230000009471 action Effects 0.000 description 5
- 230000001010 compromised effect Effects 0.000 description 5
- 238000011056 performance test Methods 0.000 description 5
- 239000004033 plastic Substances 0.000 description 5
- 229920003023 plastic Polymers 0.000 description 5
- 239000013583 drug formulation Substances 0.000 description 4
- 230000004199 lung function Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 229920000515 polycarbonate Polymers 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 230000000881 depressing effect Effects 0.000 description 3
- 238000012377 drug delivery Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000008020 evaporation Effects 0.000 description 3
- 238000001704 evaporation Methods 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000006199 nebulizer Substances 0.000 description 3
- 239000000825 pharmaceutical preparation Substances 0.000 description 3
- 229940127557 pharmaceutical product Drugs 0.000 description 3
- 239000004417 polycarbonate Substances 0.000 description 3
- 239000003380 propellant Substances 0.000 description 3
- 230000004323 axial length Effects 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 230000001960 triggered effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000004425 Makrolon Substances 0.000 description 1
- 244000273618 Sphenoclea zeylanica Species 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
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- 238000007599 discharging Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 239000004088 foaming agent Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
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- 239000000843 powder Substances 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000009325 pulmonary function Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000012372 quality testing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000009987 spinning Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000012899 standard injection Substances 0.000 description 1
- 239000010902 straw Substances 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
- A61M15/0026—Hinged caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
- B01F25/31—Injector mixers in conduits or tubes through which the main component flows
- B01F25/312—Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof
- B01F25/3124—Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof characterised by the place of introduction of the main flow
- B01F25/31242—Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof characterised by the place of introduction of the main flow the main flow being injected in the central area of the venturi, creating an aspiration in the circumferential part of the conduit
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04F—PUMPING OF FLUID BY DIRECT CONTACT OF ANOTHER FLUID OR BY USING INERTIA OF FLUID TO BE PUMPED; SIPHONS
- F04F5/00—Jet pumps, i.e. devices in which flow is induced by pressure drop caused by velocity of another fluid flow
- F04F5/44—Component parts, details, or accessories not provided for in, or of interest apart from, groups F04F5/02 - F04F5/42
- F04F5/46—Arrangements of nozzles
- F04F5/463—Arrangements of nozzles with provisions for mixing
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
- F15D—FLUID DYNAMICS, i.e. METHODS OR MEANS FOR INFLUENCING THE FLOW OF GASES OR LIQUIDS
- F15D1/00—Influencing flow of fluids
- F15D1/02—Influencing flow of fluids in pipes or conduits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/20—Flow characteristics having means for promoting or enhancing the flow, actively or passively
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Jet Pumps And Other Pumps (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28478409P | 2009-12-23 | 2009-12-23 | |
| US61/284,784 | 2009-12-23 | ||
| PCT/US2010/062084 WO2011079310A1 (en) | 2009-12-23 | 2010-12-23 | Enhanced eductor design |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2781313A1 CA2781313A1 (en) | 2011-06-30 |
| CA2781313C true CA2781313C (en) | 2019-09-17 |
Family
ID=44185936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2781313A Active CA2781313C (en) | 2009-12-23 | 2010-12-23 | Enhanced eductor design |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US9227030B2 (forum.php) |
| EP (1) | EP2515978B1 (forum.php) |
| JP (3) | JP5781540B2 (forum.php) |
| CN (1) | CN102686261B (forum.php) |
| AU (1) | AU2010336338B2 (forum.php) |
| CA (1) | CA2781313C (forum.php) |
| IL (3) | IL219744A (forum.php) |
| IN (1) | IN2012DN04857A (forum.php) |
| WO (1) | WO2011079310A1 (forum.php) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1494732T1 (sl) | 2002-03-20 | 2008-08-31 | Mannking Corp | Inhalacijski aparat |
| BRPI0514263B8 (pt) | 2004-08-20 | 2021-05-25 | Mannkind Corp | método para a síntese de bis-3,6-[4-aminobutil]-2,5-dicetopiperazina n-protegida |
| PL2322180T3 (pl) | 2004-08-23 | 2015-10-30 | Mannkind Corp | Sole diketopiperazyny do dostarczania leków |
| CN104324366B (zh) | 2005-09-14 | 2016-10-05 | 曼金德公司 | 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法 |
| BRPI0707991B8 (pt) | 2006-02-22 | 2021-05-25 | Mannkind Corp | métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco |
| WO2008023015A1 (en) * | 2006-08-22 | 2008-02-28 | Glaxo Group Limited | Actuator for an inhaler |
| CN101528292A (zh) * | 2006-08-22 | 2009-09-09 | 葛兰素集团有限公司 | 用于吸入器的致动器 |
| US8875697B2 (en) * | 2007-07-24 | 2014-11-04 | Ric Investments, Llc | Drug delivery apparatus and method |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| DE202009018480U1 (de) | 2008-06-13 | 2012-01-26 | Mannkind Corp. | Trockenpulverinhalator und System zur Medikamentenabgabe |
| RU2470681C2 (ru) | 2008-06-20 | 2012-12-27 | Маннкайнд Корпорейшн | Интерактивное устройство и способ профилирования усилий при ингаляции в реальном масштабе времени |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| EP2461857B1 (en) * | 2009-08-07 | 2019-10-02 | Kind Consumer Limited | An inhaler |
| IN2012DN04857A (forum.php) * | 2009-12-23 | 2015-09-25 | Map Pharmaceuticals Inc | |
| AU2011271097B2 (en) * | 2010-06-21 | 2014-11-27 | Mannkind Corporation | Dry powder drug delivery system and methods |
| WO2012135765A2 (en) | 2011-04-01 | 2012-10-04 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| IN2014DN03093A (forum.php) | 2011-10-24 | 2015-05-15 | Mannkind Corp | |
| CA2878457C (en) | 2012-07-12 | 2021-01-19 | Mannkind Corporation | Dry powder drug delivery systems and methods |
| JP2015531247A (ja) | 2012-08-29 | 2015-11-02 | シエシー ファルマセウティチィ ソシエタ ペル アチオニ | エアゾール吸入装置 |
| CA3056509C (en) * | 2013-03-14 | 2021-11-16 | Trudell Medical International | Metered dose inhaler applicator |
| EP2993997B1 (en) * | 2013-05-10 | 2023-08-02 | Fontem Ventures B.V. | Flavor vortex device |
| GB201308679D0 (en) * | 2013-05-14 | 2013-06-26 | 3M Innovative Properties Co | Actuator for an inhaler |
| KR102465025B1 (ko) | 2013-07-18 | 2022-11-09 | 맨카인드 코포레이션 | 열-안정성 건조 분말 약제학적 조성물 및 방법 |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| CN103877655B (zh) * | 2014-04-08 | 2015-12-30 | 隋宁昕 | 自吸固定式吸氧鼻塞 |
| US11291780B2 (en) * | 2014-12-04 | 2022-04-05 | Vyaire Medical Consumables Llc | Breath-actuated nebulizer for medicine inhalation |
| CN108697868B (zh) * | 2015-12-21 | 2021-09-21 | 3M创新有限公司 | 药用吸入器 |
| GB201702407D0 (en) | 2017-02-14 | 2017-03-29 | Norton (Waterford) Ltd | Inhalers and related methods |
| GB201707095D0 (en) | 2017-05-04 | 2017-06-21 | 3M Innovative Properties Co | Inhaler flow control mechanism |
| CN109210374B (zh) * | 2017-06-30 | 2021-06-08 | 北京北方华创微电子装备有限公司 | 进气管路及半导体加工设备 |
| US11185643B2 (en) * | 2018-04-06 | 2021-11-30 | Frank Levy | Apparatus and method for producing an enriched medical suspension |
| CN110433366B (zh) * | 2019-08-12 | 2022-03-04 | 杭州市红十字会医院 | 一种便携式呼吸科给药器 |
| CN113898570B (zh) * | 2021-12-08 | 2022-02-08 | 常州萨柏美格医用气体设备有限公司 | 气体流动过程检测装置及方法、空气压缩机组及检测方法 |
| CN114798201B (zh) * | 2022-06-29 | 2022-10-04 | 山东沃德净水科技有限公司 | 一种喷射器优化方法及喷射器 |
| WO2025030129A2 (en) * | 2023-08-03 | 2025-02-06 | United Industries Corporation | Aerosol spray device, insecticide composition, and method of use |
| US12268807B1 (en) | 2023-12-20 | 2025-04-08 | Yale University | Devices, systems, and methods for providing individualized delivery of suspended medication |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2037940A (en) * | 1932-09-10 | 1936-04-21 | Edward A Stalker | Means for preventing the separation of the flow from curved surfaces |
| US3665949A (en) | 1969-06-27 | 1972-05-30 | Bendix Corp | Gaseous controlled fluidic throttling valve |
| YU41046B (en) * | 1974-08-22 | 1986-10-31 | Schering Ag | Medicine inholating device |
| US4044763A (en) * | 1975-07-07 | 1977-08-30 | Bird F M | Ventilator and method |
| US4592348A (en) * | 1984-12-17 | 1986-06-03 | Waters Iv William C | Aerosol inhaler |
| FR2645026B1 (fr) * | 1989-03-31 | 1997-11-21 | Boussignac Georges | Dispositif d'assistance respiratoire |
| US5404871A (en) * | 1991-03-05 | 1995-04-11 | Aradigm | Delivery of aerosol medications for inspiration |
| US5161524A (en) | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
| US5785049A (en) * | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
| FI951127A0 (fi) * | 1992-09-11 | 1995-03-10 | Glaxo Group Ltd | Inhalaatiolaite |
| WO1995005208A1 (en) * | 1993-08-18 | 1995-02-23 | Fisons Plc | Inhalator with breath flow regulation |
| US5415162A (en) * | 1994-01-18 | 1995-05-16 | Glaxo Inc. | Multi-dose dry powder inhalation device |
| CZ289029B6 (cs) * | 1994-09-21 | 2001-10-17 | Inhale Therapeutic Systems | Způsob aerosolizace práąku, zejména práąkového léku a zařízení k provádění tohoto způsobu |
| US6006747A (en) * | 1997-03-20 | 1999-12-28 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| US5954047A (en) * | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
| JP3530004B2 (ja) * | 1998-02-06 | 2004-05-24 | 株式会社日立ユニシアオートモティブ | 吸入式投薬器 |
| CA2379137C (en) * | 1999-07-23 | 2007-01-23 | Pharmaceutical Discovery Corporation | Unit dose capsules and dry powder inhaler |
| US6367471B1 (en) | 1999-11-01 | 2002-04-09 | Sheffield Pharmaceuticals, Inc. | Internal vortex mechanism for inhaler device |
| US6443151B1 (en) | 2000-03-08 | 2002-09-03 | Aradigm Corporation | Fluid velocity-sensitive trigger mechanism |
| DE10024738A1 (de) * | 2000-05-19 | 2001-11-29 | Qvf Engineering Gmbh | Glasbauteile mit einer ableitfähigen Beschichtung, ihre Verwendung und daraus hergestellte Apparate, Anlagen und Rohrleitungen |
| GB0016478D0 (en) * | 2000-07-05 | 2000-08-23 | Innovata Biomed Ltd | Valve |
| GB2364919A (en) * | 2000-07-21 | 2002-02-13 | Cambridge Consultants | Inhalers |
| FI20002363A0 (fi) * | 2000-10-27 | 2000-10-27 | Orion Yhtymae Oyj | Jauheinhalaattori |
| GB0222295D0 (en) | 2002-09-25 | 2002-10-30 | 3M Innovative Properties Co | Breath actuated medicament dispensing devices |
| DE102005010965B3 (de) * | 2005-03-10 | 2006-08-03 | Medspray Xmems Bv | Inhalator mit einem Mischkanal zum Erzeugen eines zu inhalierenden Aerosols |
| DE102006014433A1 (de) * | 2006-03-27 | 2007-10-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen |
| ES2592274T3 (es) * | 2006-03-30 | 2016-11-29 | Carefusion 2200, Inc. | Nebulizador con control de fluido basado en el flujo |
| US7841336B2 (en) * | 2006-03-30 | 2010-11-30 | Carefusion 2200, Inc. | Nebulize with pressure-based fluidic control and related methods |
| WO2008106411A2 (en) * | 2007-02-28 | 2008-09-04 | Abbott Respiratory Llc | Nozzle-based atomization system |
| JP5462152B2 (ja) * | 2008-04-17 | 2014-04-02 | 帝人ファーマ株式会社 | 定量噴霧式吸入器用吸入補助器具 |
| DE202009018480U1 (de) * | 2008-06-13 | 2012-01-26 | Mannkind Corp. | Trockenpulverinhalator und System zur Medikamentenabgabe |
| IN2012DN04857A (forum.php) * | 2009-12-23 | 2015-09-25 | Map Pharmaceuticals Inc |
-
2010
- 2010-12-23 IN IN4857DEN2012 patent/IN2012DN04857A/en unknown
- 2010-12-23 JP JP2012546246A patent/JP5781540B2/ja not_active Expired - Fee Related
- 2010-12-23 WO PCT/US2010/062084 patent/WO2011079310A1/en active Application Filing
- 2010-12-23 US US12/978,254 patent/US9227030B2/en active Active
- 2010-12-23 EP EP10840198.5A patent/EP2515978B1/en active Active
- 2010-12-23 AU AU2010336338A patent/AU2010336338B2/en not_active Ceased
- 2010-12-23 CN CN201080058137.2A patent/CN102686261B/zh active Active
- 2010-12-23 CA CA2781313A patent/CA2781313C/en active Active
-
2012
- 2012-05-13 IL IL219744A patent/IL219744A/en active IP Right Grant
-
2015
- 2015-07-14 JP JP2015140719A patent/JP6157542B2/ja active Active
- 2015-10-22 IL IL242205A patent/IL242205A/en active IP Right Grant
- 2015-11-18 US US14/944,335 patent/US9610415B2/en not_active Expired - Fee Related
-
2016
- 2016-11-15 US US15/351,632 patent/US20170056609A1/en not_active Abandoned
-
2017
- 2017-06-05 JP JP2017110588A patent/JP2017164554A/ja active Pending
- 2017-06-12 IL IL252847A patent/IL252847B/en active IP Right Grant
-
2019
- 2019-03-01 US US16/290,620 patent/US20200030555A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011079310A1 (en) | 2011-06-30 |
| EP2515978B1 (en) | 2018-02-14 |
| US20170056609A1 (en) | 2017-03-02 |
| CN102686261B (zh) | 2014-09-10 |
| EP2515978A4 (en) | 2015-03-04 |
| IL219744A (en) | 2015-11-30 |
| IN2012DN04857A (forum.php) | 2015-09-25 |
| JP5781540B2 (ja) | 2015-09-24 |
| US20160129208A1 (en) | 2016-05-12 |
| AU2010336338A1 (en) | 2012-06-21 |
| JP6157542B2 (ja) | 2017-07-05 |
| CN102686261A (zh) | 2012-09-19 |
| US9610415B2 (en) | 2017-04-04 |
| JP2015221225A (ja) | 2015-12-10 |
| US20110155129A1 (en) | 2011-06-30 |
| EP2515978A1 (en) | 2012-10-31 |
| CA2781313A1 (en) | 2011-06-30 |
| IL242205A (en) | 2017-07-31 |
| JP2013515577A (ja) | 2013-05-09 |
| IL219744A0 (en) | 2012-07-31 |
| IL242205A0 (en) | 2015-11-30 |
| IL252847A0 (en) | 2017-08-31 |
| IL252847B (en) | 2021-02-28 |
| US9227030B2 (en) | 2016-01-05 |
| JP2017164554A (ja) | 2017-09-21 |
| US20200030555A1 (en) | 2020-01-30 |
| AU2010336338B2 (en) | 2015-02-19 |
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