CA2776618C - Compositions et procedes pour favoriser l'adhesion liposomale et cellulaire - Google Patents
Compositions et procedes pour favoriser l'adhesion liposomale et cellulaire Download PDFInfo
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- CA2776618C CA2776618C CA2776618A CA2776618A CA2776618C CA 2776618 C CA2776618 C CA 2776618C CA 2776618 A CA2776618 A CA 2776618A CA 2776618 A CA2776618 A CA 2776618A CA 2776618 C CA2776618 C CA 2776618C
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- liposomes
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- reactive functional
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- liposome
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- 238000003917 TEM image Methods 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- HEDRZPFGACZZDS-MICDWDOJSA-N Trichloro(2H)methane Chemical compound [2H]C(Cl)(Cl)Cl HEDRZPFGACZZDS-MICDWDOJSA-N 0.000 description 1
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- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 description 1
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- CPBQJMYROZQQJC-UHFFFAOYSA-N helium neon Chemical compound [He].[Ne] CPBQJMYROZQQJC-UHFFFAOYSA-N 0.000 description 1
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- 239000002244 precipitate Substances 0.000 description 1
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- 229910052709 silver Inorganic materials 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention décrit des composés, des compositions et des procédés pour incorporer des groupes fonctionnels complémentaires chimiosélectifs et bio-orthogonaux dans des liposomes. La présente demande concerne également diverses utilisations de ces liposomes modifiés, notamment pour attacher les groupes fonctionnels complémentaires chimiosélectifs et bio-orthogonaux aux surfaces cellulaires par délivrance liposomale dans lobjectif de modifier les connexions de la surface cellulaire.
Priority Applications (1)
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CA2776618A CA2776618C (fr) | 2012-05-10 | 2012-05-10 | Compositions et procedes pour favoriser l'adhesion liposomale et cellulaire |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2776618A CA2776618C (fr) | 2012-05-10 | 2012-05-10 | Compositions et procedes pour favoriser l'adhesion liposomale et cellulaire |
Publications (2)
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CA2776618A1 CA2776618A1 (fr) | 2013-11-10 |
CA2776618C true CA2776618C (fr) | 2019-07-23 |
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Effective date: 20170504 |