CA2769498C - Process for obtaining 3,3-diphenylpropylamines - Google Patents
Process for obtaining 3,3-diphenylpropylamines Download PDFInfo
- Publication number
- CA2769498C CA2769498C CA2769498A CA2769498A CA2769498C CA 2769498 C CA2769498 C CA 2769498C CA 2769498 A CA2769498 A CA 2769498A CA 2769498 A CA2769498 A CA 2769498A CA 2769498 C CA2769498 C CA 2769498C
- Authority
- CA
- Canada
- Prior art keywords
- compound
- general formula
- enantiomers
- acid
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09382123.9 | 2009-07-27 | ||
| EP09382123.9A EP2281801B1 (en) | 2009-07-27 | 2009-07-27 | Process for obtaining 3,3-diphenylpropylamines |
| PCT/EP2010/060817 WO2011012584A1 (en) | 2009-07-27 | 2010-07-26 | Process for obtaining 3,3-diphenylpropylamines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2769498A1 CA2769498A1 (en) | 2011-02-03 |
| CA2769498C true CA2769498C (en) | 2017-08-29 |
Family
ID=41402340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2769498A Expired - Fee Related CA2769498C (en) | 2009-07-27 | 2010-07-26 | Process for obtaining 3,3-diphenylpropylamines |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8722920B2 (zh) |
| EP (1) | EP2281801B1 (zh) |
| JP (1) | JP5700578B2 (zh) |
| CN (1) | CN102712572B (zh) |
| CA (1) | CA2769498C (zh) |
| ES (1) | ES2456866T3 (zh) |
| SI (1) | SI2281801T1 (zh) |
| WO (1) | WO2011012584A1 (zh) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1396373B1 (it) * | 2009-10-29 | 2012-11-19 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina. |
| IT1397521B1 (it) | 2009-12-21 | 2013-01-16 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina con un basso contenuto di impurezze. |
| EP2364966A1 (en) | 2010-03-09 | 2011-09-14 | LEK Pharmaceuticals d.d. | Process for preparation of 3-(2-hydroxy-5-substituted phenyl)-3-phenylpropylamines, intermediates for making hydroxytolterodine |
| IT1403094B1 (it) | 2010-12-09 | 2013-10-04 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina o un suo sale |
| EP2686288B1 (en) | 2011-04-07 | 2015-03-25 | Alembic Pharmaceuticals Limited | A process for preparing fesoterodine |
| CA2873721C (en) * | 2012-05-04 | 2021-06-22 | Crystal Pharma, S.A.U. | Process for the preparation of optically active 3,3-diphenylpropylamines |
| ES2895773T3 (es) * | 2016-05-12 | 2022-02-22 | Res Triangle Inst | Fenetilaminas vinílogas como liberadores de neurotransmisores |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9203318D0 (sv) | 1992-11-06 | 1992-11-06 | Kabi Pharmacia Ab | Novel 3,3-diphenylpropylamines, their use and preparation |
| SE9701144D0 (sv) * | 1997-03-27 | 1997-03-27 | Pharmacia & Upjohn Ab | Novel compounds, their use and preparation |
| EP0957073A1 (en) | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
| PL365470A1 (en) | 2000-06-14 | 2005-01-10 | Agouron Pharmaceuticals, Inc. | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis |
| DE10028443C1 (de) * | 2000-06-14 | 2002-05-29 | Sanol Arznei Schwarz Gmbh | Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen |
| ES2268987B1 (es) | 2005-08-05 | 2008-02-01 | Ragactives, S.L. | Procedimiento para la obtencion de 3,3-difenilpropilaminas. |
| CN101454304B (zh) | 2006-05-24 | 2012-05-30 | 辉瑞有限公司 | 用于制造苯并吡喃-2-醇衍生物的方法 |
| WO2007140986A1 (en) * | 2006-06-09 | 2007-12-13 | Schwarz Pharma Ltd | Synthesis of phenolic esters of hydroxymethyl phenols |
| WO2007147547A1 (en) * | 2006-06-20 | 2007-12-27 | Lek Pharmaceuticals D.D. | Process for preparation of 3-(2-hydroxy-5-substituted phenyl)-n-alkyl-3-phenylpropylamines |
-
2009
- 2009-07-27 EP EP09382123.9A patent/EP2281801B1/en active Active
- 2009-07-27 ES ES09382123.9T patent/ES2456866T3/es active Active
- 2009-07-27 SI SI200930875T patent/SI2281801T1/sl unknown
-
2010
- 2010-07-26 US US13/387,573 patent/US8722920B2/en active Active
- 2010-07-26 CN CN201080039826.9A patent/CN102712572B/zh not_active Expired - Fee Related
- 2010-07-26 CA CA2769498A patent/CA2769498C/en not_active Expired - Fee Related
- 2010-07-26 JP JP2012522135A patent/JP5700578B2/ja active Active
- 2010-07-26 WO PCT/EP2010/060817 patent/WO2011012584A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| SI2281801T1 (sl) | 2014-04-30 |
| JP5700578B2 (ja) | 2015-04-15 |
| US20120220797A1 (en) | 2012-08-30 |
| CA2769498A1 (en) | 2011-02-03 |
| WO2011012584A1 (en) | 2011-02-03 |
| EP2281801A1 (en) | 2011-02-09 |
| ES2456866T3 (es) | 2014-04-23 |
| CN102712572A (zh) | 2012-10-03 |
| EP2281801B1 (en) | 2014-01-08 |
| US8722920B2 (en) | 2014-05-13 |
| CN102712572B (zh) | 2014-08-27 |
| JP2013500305A (ja) | 2013-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20150702 |
|
| MKLA | Lapsed |
Effective date: 20190726 |