CA2767318A1 - Systeme de lentille intraoculaire d'accommodation a element de separation - Google Patents

Systeme de lentille intraoculaire d'accommodation a element de separation Download PDF

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Publication number
CA2767318A1
CA2767318A1 CA2767318A CA2767318A CA2767318A1 CA 2767318 A1 CA2767318 A1 CA 2767318A1 CA 2767318 A CA2767318 A CA 2767318A CA 2767318 A CA2767318 A CA 2767318A CA 2767318 A1 CA2767318 A1 CA 2767318A1
Authority
CA
Canada
Prior art keywords
lens
anterior
posterior
viewing
optical axis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2767318A
Other languages
English (en)
Other versions
CA2767318C (fr
Inventor
Gholam-Reza Zadno-Azizi
Albert C. Ting
Tuan Anh Nguyen
Valdemar Portney
Hai-Minh Pham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Visiogen Inc
Original Assignee
Visiogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/207,701 external-priority patent/US7198640B2/en
Priority claimed from US10/207,708 external-priority patent/US6884261B2/en
Priority claimed from US10/207,717 external-priority patent/US20030078657A1/en
Priority claimed from US10/207,688 external-priority patent/US6818158B2/en
Priority claimed from US10/207,718 external-priority patent/US20030078658A1/en
Application filed by Visiogen Inc filed Critical Visiogen Inc
Priority to CA2849167A priority Critical patent/CA2849167C/fr
Publication of CA2767318A1 publication Critical patent/CA2767318A1/fr
Application granted granted Critical
Publication of CA2767318C publication Critical patent/CA2767318C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1629—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1637—Correcting aberrations caused by inhomogeneities; correcting intrinsic aberrations, e.g. of the cornea, of the surface of the natural lens, aspheric, cylindrical, toric lenses
    • A61F2/164—Aspheric lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1648—Multipart lenses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00—Producing optical elements, e.g. lenses or prisms
    • B29D11/02—Artificial eyes from organic plastic material
    • B29D11/023—Implants for natural eyes
    • B29D11/026—Comprising more than one lens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1601—Lens body having features to facilitate aqueous fluid flow across the intraocular lens, e.g. for pressure equalization or nutrient delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1654—Diffractive lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/16965—Lens includes ultraviolet absorber
    • A61F2002/1699—Additional features not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • A61F2240/002—Designing or making customized prostheses
    • A61F2240/004—Using a positive or negative model, e.g. moulds

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing & Machinery (AREA)
  • Mechanical Engineering (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
CA2767318A 2002-07-25 2003-07-24 Systeme de lentille intraoculaire d'accommodation a element de separation Expired - Fee Related CA2767318C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2849167A CA2849167C (fr) 2002-07-25 2003-07-24 Lentilles intraoculaires et procedes de preparation ou de fabrication decelles-ci

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US10/207,718 2002-07-25
US10/207,701 2002-07-25
US10/207,701 US7198640B2 (en) 2001-01-25 2002-07-25 Accommodating intraocular lens system with separation member
US10/207,708 2002-07-25
US10/207,688 2002-07-25
US10/207,708 US6884261B2 (en) 2001-01-25 2002-07-25 Method of preparing an intraocular lens for implantation
US10/207,717 US20030078657A1 (en) 2001-01-25 2002-07-25 Materials for use in accommodating intraocular lens system
US10/207,688 US6818158B2 (en) 2001-01-25 2002-07-25 Accommodating intraocular lens system and method of making same
US10/207,717 2002-07-25
US10/207,718 US20030078658A1 (en) 2001-01-25 2002-07-25 Single-piece accomodating intraocular lens system
CA2493673A CA2493673C (fr) 2002-07-25 2003-07-24 Procede de preparation de lentilles intraoculaires pour implantation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2493673A Division CA2493673C (fr) 2002-07-25 2003-07-24 Procede de preparation de lentilles intraoculaires pour implantation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2849167A Division CA2849167C (fr) 2002-07-25 2003-07-24 Lentilles intraoculaires et procedes de preparation ou de fabrication decelles-ci

Publications (2)

Publication Number Publication Date
CA2767318A1 true CA2767318A1 (fr) 2004-02-05
CA2767318C CA2767318C (fr) 2014-07-22

Family

ID=31192462

Family Applications (3)

Application Number Title Priority Date Filing Date
CA2849167A Expired - Fee Related CA2849167C (fr) 2002-07-25 2003-07-24 Lentilles intraoculaires et procedes de preparation ou de fabrication decelles-ci
CA2493673A Expired - Fee Related CA2493673C (fr) 2002-07-25 2003-07-24 Procede de preparation de lentilles intraoculaires pour implantation
CA2767318A Expired - Fee Related CA2767318C (fr) 2002-07-25 2003-07-24 Systeme de lentille intraoculaire d'accommodation a element de separation

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CA2849167A Expired - Fee Related CA2849167C (fr) 2002-07-25 2003-07-24 Lentilles intraoculaires et procedes de preparation ou de fabrication decelles-ci
CA2493673A Expired - Fee Related CA2493673C (fr) 2002-07-25 2003-07-24 Procede de preparation de lentilles intraoculaires pour implantation

Country Status (5)

Country Link
EP (1) EP1524953A2 (fr)
JP (1) JP5276762B2 (fr)
AU (1) AU2003252137A1 (fr)
CA (3) CA2849167C (fr)
WO (1) WO2004010905A2 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8556967B2 (en) 1999-04-09 2013-10-15 Faezeh Mona Sarfarazi Interior bag for a capsular bag and injector
US7780729B2 (en) * 2004-04-16 2010-08-24 Visiogen, Inc. Intraocular lens
US7217112B2 (en) 2003-05-27 2007-05-15 Faezeh Mona Sarfarazi Mold for intraocular lens
IL161706A0 (en) 2004-04-29 2004-09-27 Nulens Ltd Intraocular lens fixation device
US8057217B2 (en) * 2004-09-30 2011-11-15 Bausch + Lomb Incorporated Apparatus and method for injection molding an intraocular lens device
WO2006103674A2 (fr) 2005-03-30 2006-10-05 Nulens Ltd Ensembles lentille intraoculaire accommodative (aiol) et composants separes pour lesdits ensembles
US20070260309A1 (en) * 2006-05-08 2007-11-08 Richardson Gary A Accommodating intraocular lens having a recessed anterior optic
US7998198B2 (en) * 2008-02-07 2011-08-16 Novartis Ag Accommodative IOL with dynamic spherical aberration
TWI507183B (zh) * 2009-09-04 2015-11-11 Alcon Inc 具晶體間混濁化抗性之眼內晶體
WO2011062486A1 (fr) * 2009-11-17 2011-05-26 Akkolens International B.V. Lentille intraoculaire dont l'accommodation est provoquée par la masse ciliaire
EP2563275A4 (fr) * 2010-04-27 2017-11-22 Lensgen, Inc Dispositif de lentille intraoculaire accomodative
WO2012045183A1 (fr) * 2010-10-06 2012-04-12 Eduard Anton Haefliger Implant de lentille intraoculaire
US20130338767A1 (en) * 2010-12-29 2013-12-19 Elenza Inc. Devices and methods for dynamic focusing movement
US20120253459A1 (en) 2011-02-04 2012-10-04 Cary Reich Intraocular accommodating lens and methods of use
US9372282B1 (en) 2011-08-31 2016-06-21 Novartis Ag Styrenic ophthalmic and otorhinolaryngological materials and devices formed therewith
DE102012016893A1 (de) * 2012-08-24 2014-05-15 Be Innovative Gmbh Intraokularlinse, insbesondere Kapselsackintraokularlinse
US9486311B2 (en) 2013-02-14 2016-11-08 Shifamed Holdings, Llc Hydrophilic AIOL with bonding
AU2014236688B2 (en) 2013-03-21 2019-07-25 Shifamed Holdings, Llc Accommodating intraocular lens
US10195018B2 (en) 2013-03-21 2019-02-05 Shifamed Holdings, Llc Accommodating intraocular lens
JP5481588B1 (ja) 2013-05-13 2014-04-23 株式会社Ｆｒｏｎｔｉｅｒ Ｖｉｓｉｏｎ 調節眼内レンズ
US10285805B2 (en) 2014-03-28 2019-05-14 Forsight Labs, Llc Accommodating intraocular lens
WO2016033217A1 (fr) 2014-08-26 2016-03-03 Shifamed Holdings, Llc Lentille intraoculaire adaptative
US11141263B2 (en) 2015-11-18 2021-10-12 Shifamed Holdings, Llc Multi-piece accommodating intraocular lens
JP7340450B2 (ja) 2016-10-28 2023-09-07 フォーサイト ビジョン６，インコーポレイテッド 調節性眼内レンズおよびインプラントの方法
US10350056B2 (en) 2016-12-23 2019-07-16 Shifamed Holdings, Llc Multi-piece accommodating intraocular lenses and methods for making and using same
CA3064855A1 (fr) 2017-05-30 2018-12-06 Shifamed Holdings, Llc Traitements de surface pour lentilles intraoculaires d'accommodation et methodes et dispositifs associes
WO2018227014A1 (fr) 2017-06-07 2018-12-13 Shifamed Holdings, Llc Lentilles intraoculaires à puissance optique réglable
GB2565152B (en) * 2017-08-04 2020-06-03 Rayner Intraocular Lenses Ltd Intraocular lens
CN113710200A (zh) 2019-03-25 2021-11-26 爱克透镜国际公司 恢复屈光及调节的人工晶状体组合
WO2020231260A1 (fr) 2019-05-15 2020-11-19 Akkolens International B.V. Lentilles intraoculaires d'accommodation avec combinaison de composants d'entraînement mécanique
WO2021034187A1 (fr) 2019-08-19 2021-02-25 Akkolens International B.V. Combinaison de lentille intraoculaire accommodative à sections de lentille à puissance fixe et variable indépendantes
NL2027301B1 (en) 2020-01-13 2021-10-26 Akkolens Int B V Mechanical means for accommodative intraocular lens
KR102482346B1 (ko) * 2020-01-22 2022-12-29 주식회사 오토스윙 용접 정보 제공 장치
NL2028038B1 (en) 2020-05-11 2022-07-04 Akkolens Int B V Method to connect and distance hydrophilic intraocular lens elements

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Publication number Priority date Publication date Assignee Title
CS271606B1 (en) * 1988-04-11 1990-10-12 Sulc Jiri Intraocular optical system
US5275623A (en) * 1991-11-18 1994-01-04 Faezeh Sarfarazi Elliptical accommodative intraocular lens for small incision surgery
FR2747564B1 (fr) * 1996-04-22 1999-01-29 W K Et Associes Emballage pour le pliage des implants intraoculaires
US5876406A (en) * 1996-08-02 1999-03-02 Staar Surgical Company, Inc. Deformable intraocular lens injecting apparatus with transverse hinged lens cartridge
US6488708B2 (en) * 1999-04-09 2002-12-03 Faezeh Sarfarazi Open chamber, elliptical, accommodative intraocular lens system
US6616692B1 (en) * 1999-04-30 2003-09-09 Advanced Medical Optics, Inc. Intraocular lens combinations
US6599317B1 (en) * 1999-09-17 2003-07-29 Advanced Medical Optics, Inc. Intraocular lens with a translational zone
JP3728155B2 (ja) * 1999-10-05 2005-12-21 キヤノンスター株式会社 眼内挿入用レンズの挿入システム
US6797004B1 (en) * 2000-03-02 2004-09-28 Advanced Medical Optics, Inc. Holders for intraocular lenses
WO2002071983A1 (fr) * 2001-01-25 2002-09-19 Gholam-Reza Zadno-Azizi Systeme de lentille intraoculaire a pouvoir d'accommodation
US6884263B2 (en) * 2001-07-17 2005-04-26 Medennium, Inc. Accommodative intraocular lens

Also Published As

Publication number Publication date
CA2767318C (fr) 2014-07-22
JP2005533611A (ja) 2005-11-10
WO2004010905A2 (fr) 2004-02-05
CA2493673C (fr) 2012-04-10
CA2849167A1 (fr) 2004-02-05
CA2849167C (fr) 2016-06-28
AU2003252137A1 (en) 2004-02-16
EP1524953A2 (fr) 2005-04-27
JP5276762B2 (ja) 2013-08-28
WO2004010905A3 (fr) 2004-05-13
CA2493673A1 (fr) 2004-02-05

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