CA2759490A1 - Tissue kallikrein for the treatment of huntington's disease - Google Patents
Tissue kallikrein for the treatment of huntington's disease Download PDFInfo
- Publication number
- CA2759490A1 CA2759490A1 CA2759490A CA2759490A CA2759490A1 CA 2759490 A1 CA2759490 A1 CA 2759490A1 CA 2759490 A CA2759490 A CA 2759490A CA 2759490 A CA2759490 A CA 2759490A CA 2759490 A1 CA2759490 A1 CA 2759490A1
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- CA
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- Prior art keywords
- klk1
- disease
- seq
- huntington
- tissue kallikrein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4853—Kallikrein (3.4.21.34 or 3.4.21.35)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17157909P | 2009-04-22 | 2009-04-22 | |
| US61/171,579 | 2009-04-22 | ||
| PCT/CA2010/000575 WO2010121361A1 (en) | 2009-04-22 | 2010-04-22 | Tissue kallikrein for the treatment of huntington's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2759490A1 true CA2759490A1 (en) | 2010-10-28 |
Family
ID=43010630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2759490A Abandoned CA2759490A1 (en) | 2009-04-22 | 2010-04-22 | Tissue kallikrein for the treatment of huntington's disease |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20120225051A1 (enExample) |
| EP (1) | EP2421554A4 (enExample) |
| JP (1) | JP2012524725A (enExample) |
| CN (1) | CN102458454A (enExample) |
| CA (1) | CA2759490A1 (enExample) |
| WO (1) | WO2010121361A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ582930A (en) * | 2007-07-20 | 2012-11-30 | Diamedica Inc | Tissue kallikrein for the treatment of diseases associated with amyloid protein |
| US20130315891A1 (en) | 2012-05-25 | 2013-11-28 | Matthew Charles | Formulations of human tissue kallikrein-1 for parenteral delivery and related methods |
| US20130323222A1 (en) | 2012-06-04 | 2013-12-05 | Matthew Charles | Human tissue kallikrein 1 glycosylation isoforms |
| WO2015109107A1 (en) * | 2014-01-15 | 2015-07-23 | Cal Poly Pomona Foundation, Inc. | Treatment and diagnosis of huntington's disease |
| CN110446501A (zh) | 2017-03-09 | 2019-11-12 | 代阿麦迪卡股份有限公司 | 组织激肽释放酶1的剂型 |
| CN116549619A (zh) * | 2022-01-28 | 2023-08-08 | 江苏众红生物工程创药研究院有限公司 | 激肽原酶及其衍生物在治疗vci、psci或csvd中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001056532A2 (en) * | 2000-02-04 | 2001-08-09 | The Scripps Research Institute | Neuroprotective, antithrombotic and anti-inflammatory uses of activated protein c (apc) |
| EP1664790A2 (en) * | 2003-08-30 | 2006-06-07 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with kallikrein 8 (klk8) |
| US20070191296A1 (en) * | 2003-08-30 | 2007-08-16 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with kallikrein 13 (klk13) |
| NZ582930A (en) * | 2007-07-20 | 2012-11-30 | Diamedica Inc | Tissue kallikrein for the treatment of diseases associated with amyloid protein |
-
2010
- 2010-04-22 JP JP2012506297A patent/JP2012524725A/ja active Pending
- 2010-04-22 CN CN2010800275339A patent/CN102458454A/zh active Pending
- 2010-04-22 EP EP10766547A patent/EP2421554A4/en not_active Withdrawn
- 2010-04-22 US US13/265,357 patent/US20120225051A1/en not_active Abandoned
- 2010-04-22 CA CA2759490A patent/CA2759490A1/en not_active Abandoned
- 2010-04-22 WO PCT/CA2010/000575 patent/WO2010121361A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20120225051A1 (en) | 2012-09-06 |
| EP2421554A4 (en) | 2012-11-28 |
| JP2012524725A (ja) | 2012-10-18 |
| CN102458454A (zh) | 2012-05-16 |
| EP2421554A1 (en) | 2012-02-29 |
| WO2010121361A1 (en) | 2010-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20150422 |