CA2746085A1 - Enzastaurin for the treatment of cancer - Google Patents
Enzastaurin for the treatment of cancer Download PDFInfo
- Publication number
- CA2746085A1 CA2746085A1 CA2746085A CA2746085A CA2746085A1 CA 2746085 A1 CA2746085 A1 CA 2746085A1 CA 2746085 A CA2746085 A CA 2746085A CA 2746085 A CA2746085 A CA 2746085A CA 2746085 A1 CA2746085 A1 CA 2746085A1
- Authority
- CA
- Canada
- Prior art keywords
- cancer
- patient
- hdac2
- enzastaurin
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/33—Heterocyclic compounds
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
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- A—HUMAN NECESSITIES
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- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12245108P | 2008-12-15 | 2008-12-15 | |
| US61/122,451 | 2008-12-15 | ||
| PCT/US2009/066925 WO2010074936A2 (en) | 2008-12-15 | 2009-12-07 | Enzastaurin for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2746085A1 true CA2746085A1 (en) | 2010-07-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2746085A Abandoned CA2746085A1 (en) | 2008-12-15 | 2009-12-07 | Enzastaurin for the treatment of cancer |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20110288032A1 (https=) |
| EP (1) | EP2376081A2 (https=) |
| JP (1) | JP2012512157A (https=) |
| KR (1) | KR20110084533A (https=) |
| CN (1) | CN102245184A (https=) |
| AU (1) | AU2009330492A1 (https=) |
| BR (1) | BRPI0922367A2 (https=) |
| CA (1) | CA2746085A1 (https=) |
| EA (1) | EA201170821A1 (https=) |
| MX (1) | MX2011006433A (https=) |
| WO (1) | WO2010074936A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107898791A (zh) | 2010-06-03 | 2018-04-13 | 药品循环有限责任公司 | 布鲁顿酪氨酸激酶(btk)抑制剂的应用 |
| CA2862320A1 (en) * | 2012-01-24 | 2013-08-01 | Millennium Pharmaceuticals, Inc. | Method of treatment of nasopharyngeal cancer |
| JP6215235B2 (ja) * | 2012-01-24 | 2017-10-18 | ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 癌の治療方法 |
| SG11201404888SA (en) * | 2012-02-17 | 2014-09-26 | Pharmacyclics Inc | Combinations of histone deacetylase inhibitor and pazopanib and uses thereof |
| CN104704129A (zh) | 2012-07-24 | 2015-06-10 | 药品循环公司 | 与对布鲁顿酪氨酸激酶(btk)抑制剂的抗性相关的突变 |
| MX372671B (es) * | 2013-07-19 | 2020-04-23 | Onyx Therapeutics Inc | Inhibidores de proteasoma de epoxicetona peptídica en combinacion con inhibidores de cinasa pim para el tratamiento de canceres. |
| WO2015143400A1 (en) | 2014-03-20 | 2015-09-24 | Pharmacyclics, Inc. | Phospholipase c gamma 2 and resistance associated mutations |
| WO2017011314A1 (en) * | 2015-07-10 | 2017-01-19 | Paharmacyclics Llc | Btk and hdac combinations |
| WO2020223657A1 (en) * | 2019-05-02 | 2020-11-05 | Predictive Technology Group, Inc. | Somatic cancer driver mutations in endometriosis lesions contribute to secondary cancer risk |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| ES2236702T3 (es) | 1993-12-23 | 2005-07-16 | Eli Lilly And Company | Inhibidores de la proteina quinasa c. |
| US20080096923A1 (en) * | 2004-07-23 | 2008-04-24 | Aniz Girach | Methods For Diagnosing And Treating Diabetic Microvascular Complications |
| US20090202659A1 (en) * | 2005-06-10 | 2009-08-13 | Gimble Jeffrey M | Modulation of Peripheral Clocks in Adipose Tissue |
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2009
- 2009-12-07 JP JP2011540796A patent/JP2012512157A/ja not_active Withdrawn
- 2009-12-07 BR BRPI0922367A patent/BRPI0922367A2/pt not_active IP Right Cessation
- 2009-12-07 MX MX2011006433A patent/MX2011006433A/es not_active Application Discontinuation
- 2009-12-07 US US13/130,104 patent/US20110288032A1/en not_active Abandoned
- 2009-12-07 EP EP09768467A patent/EP2376081A2/en not_active Withdrawn
- 2009-12-07 CA CA2746085A patent/CA2746085A1/en not_active Abandoned
- 2009-12-07 WO PCT/US2009/066925 patent/WO2010074936A2/en not_active Ceased
- 2009-12-07 KR KR1020117013612A patent/KR20110084533A/ko not_active Ceased
- 2009-12-07 EA EA201170821A patent/EA201170821A1/ru unknown
- 2009-12-07 CN CN2009801503024A patent/CN102245184A/zh active Pending
- 2009-12-07 AU AU2009330492A patent/AU2009330492A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012512157A (ja) | 2012-05-31 |
| WO2010074936A2 (en) | 2010-07-01 |
| KR20110084533A (ko) | 2011-07-25 |
| EA201170821A1 (ru) | 2011-12-30 |
| AU2009330492A1 (en) | 2010-07-01 |
| BRPI0922367A2 (pt) | 2016-05-24 |
| US20110288032A1 (en) | 2011-11-24 |
| CN102245184A (zh) | 2011-11-16 |
| WO2010074936A3 (en) | 2010-09-16 |
| EP2376081A2 (en) | 2011-10-19 |
| MX2011006433A (es) | 2011-07-19 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20141209 |