CA2740242A1 - Genetic polymorphisms in age-related macular degeneration - Google Patents
Genetic polymorphisms in age-related macular degeneration Download PDFInfo
- Publication number
- CA2740242A1 CA2740242A1 CA2740242A CA2740242A CA2740242A1 CA 2740242 A1 CA2740242 A1 CA 2740242A1 CA 2740242 A CA2740242 A CA 2740242A CA 2740242 A CA2740242 A CA 2740242A CA 2740242 A1 CA2740242 A1 CA 2740242A1
- Authority
- CA
- Canada
- Prior art keywords
- patient
- allele
- increased likelihood
- polymorphism
- oligonucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6846—Common amplification features
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/113—PCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/137—Ligase Chain Reaction [LCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11166708P | 2008-11-05 | 2008-11-05 | |
| US61/111,667 | 2008-11-05 | ||
| US17485609P | 2009-05-01 | 2009-05-01 | |
| US61/174,856 | 2009-05-01 | ||
| PCT/US2009/063434 WO2010054110A2 (en) | 2008-11-05 | 2009-11-05 | Genetic polymorphisms in age-related macular degeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2740242A1 true CA2740242A1 (en) | 2010-05-14 |
Family
ID=41650496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2740242A Abandoned CA2740242A1 (en) | 2008-11-05 | 2009-11-05 | Genetic polymorphisms in age-related macular degeneration |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20120003641A1 (enExample) |
| EP (2) | EP2356250A2 (enExample) |
| JP (1) | JP5701216B2 (enExample) |
| KR (1) | KR101719376B1 (enExample) |
| CN (2) | CN103333952B (enExample) |
| AU (1) | AU2009313475B2 (enExample) |
| CA (1) | CA2740242A1 (enExample) |
| DK (1) | DK2540843T3 (enExample) |
| ES (1) | ES2498274T3 (enExample) |
| IL (1) | IL211995A (enExample) |
| MX (1) | MX2011004763A (enExample) |
| PL (1) | PL2540843T3 (enExample) |
| SI (1) | SI2540843T1 (enExample) |
| WO (1) | WO2010054110A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| RU2486253C2 (ru) | 2008-07-25 | 2013-06-27 | Инфоком Корпорейшн | Онкоген nrf2 и его применение |
| AR085301A1 (es) * | 2011-02-23 | 2013-09-18 | Sanofi Sa | Polimorfismos de un solo nucleotido en el promotor del gen vegfa y su uso como marcadores predictivos para tratamientos anti-vegf |
| JO3283B1 (ar) | 2011-04-26 | 2018-09-16 | Sanofi Sa | تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI) |
| CN110564819A (zh) | 2011-05-19 | 2019-12-13 | 基纳生物技术有限公司 | 用于多重核酸鉴定的产品和方法 |
| WO2013030032A1 (en) * | 2011-08-26 | 2013-03-07 | F. Hoffmann-La Roche Ag | A method for predicting clinical benefit in the treatment of neurodevelopmental, neurological or neuropsychiatric disorders |
| MX390891B (es) * | 2011-10-14 | 2025-03-19 | Genentech Inc | ANTICUERPOS ANTI-HtrA1 Y MÉTODOS DE USO. |
| US20140004105A1 (en) * | 2012-06-29 | 2014-01-02 | Sequenom, Inc. | Age-related macular degeneration diagnostics |
| CR20160132A (es) | 2013-08-12 | 2016-08-25 | Genentech Inc | Composiciones y método para tratar condiciones asociadas con el complemento |
| KR20160147855A (ko) | 2014-05-01 | 2016-12-23 | 제넨테크, 인크. | 항-인자 d 항체 변이체 및 이의 용도 |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| WO2016008975A1 (en) | 2014-07-18 | 2016-01-21 | Sanofi | Method for predicting the outcome of a treatment with aflibercept of a patient suspected to suffer from a cancer |
| EP3233115B1 (en) * | 2014-12-19 | 2021-02-17 | Children's Hospital Medical Center | Methods and compositions related to transplant-associated thrombotic microangiopathy |
| JP2018512880A (ja) | 2015-04-24 | 2018-05-24 | アジーナ バイオサイエンス， インコーポレイテッド | 少量の対立遺伝子および多型の同定ならびに定量のためのマルチプレックス法 |
| CN104878105B (zh) * | 2015-06-02 | 2017-10-31 | 北京医院 | 一种预测雷珠单抗治疗年龄相关性黄斑变性疗效的试剂 |
| CN104894261B (zh) * | 2015-06-02 | 2020-02-14 | 北京医院 | 一种预测雷珠单抗治疗年龄相关性黄斑变性疗效的试剂盒 |
| EP3368074A2 (en) | 2015-10-30 | 2018-09-05 | Hoffmann-La Roche AG | Anti-factor d antibodies and conjugates |
| HK1257422A1 (zh) | 2015-10-30 | 2019-10-18 | 豪夫迈‧罗氏有限公司 | 抗-因子d抗体变体缀合物及其用途 |
| KR20250057128A (ko) | 2015-12-30 | 2025-04-28 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| WO2017148904A1 (en) * | 2016-02-29 | 2017-09-08 | Franz Grus | Predictive markers useful in the treatment of wet age-related macular degeneration |
| WO2017222914A1 (en) | 2016-06-21 | 2017-12-28 | Inception 4, Inc. | Carbocyclic prolinamide derivatives |
| EP4257191A3 (en) | 2016-06-21 | 2023-11-22 | Orion Ophthalmology LLC | Heterocyclic prolinamide derivatives |
| US12071476B2 (en) | 2018-03-02 | 2024-08-27 | Kodiak Sciences Inc. | IL-6 antibodies and fusion constructs and conjugates thereof |
| AU2020364071A1 (en) | 2019-10-10 | 2022-05-26 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| CN113373236B (zh) * | 2021-02-19 | 2021-12-31 | 中国科学院北京基因组研究所(国家生物信息中心) | 一种获得中国人群个体年龄的方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8311018D0 (en) | 1983-04-22 | 1983-05-25 | Amersham Int Plc | Detecting mutations in dna |
| US4998617A (en) | 1986-09-15 | 1991-03-12 | Laura Lupton Inc | Facial cosmetic liquid make up kit |
| US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| US6270961B1 (en) | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
| US5176996A (en) | 1988-12-20 | 1993-01-05 | Baylor College Of Medicine | Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
| US5256775A (en) | 1989-06-05 | 1993-10-26 | Gilead Sciences, Inc. | Exonuclease-resistant oligonucleotides |
| FR2650840B1 (fr) | 1989-08-11 | 1991-11-29 | Bertin & Cie | Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications |
| US5264564A (en) | 1989-10-24 | 1993-11-23 | Gilead Sciences | Oligonucleotide analogs with novel linkages |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US6004744A (en) | 1991-03-05 | 1999-12-21 | Molecular Tool, Inc. | Method for determining nucleotide identity through extension of immobilized primer |
| US5858659A (en) | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
| US5952172A (en) | 1993-12-10 | 1999-09-14 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US5968740A (en) | 1995-07-24 | 1999-10-19 | Affymetrix, Inc. | Method of Identifying a Base in a Nucleic Acid |
| IL132240A0 (en) | 1997-04-07 | 2001-03-19 | Genentech Inc | Anti-vegf antibodies |
| AU9381598A (en) | 1997-09-10 | 1999-03-29 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Method of amplifying dna and rna mismatch cleavage products |
| AU2005314461B2 (en) * | 2004-11-18 | 2012-02-02 | The Rockefeller University | Methods and compositions for treating ocular disorders |
| WO2008103299A2 (en) * | 2007-02-16 | 2008-08-28 | Massachusetts Eye & Ear Infirmary | Methods and compositions for prognosing, detecting, and treating age-related macular degeneration |
-
2009
- 2009-11-05 CA CA2740242A patent/CA2740242A1/en not_active Abandoned
- 2009-11-05 EP EP09748682A patent/EP2356250A2/en not_active Withdrawn
- 2009-11-05 DK DK12185155.4T patent/DK2540843T3/da active
- 2009-11-05 EP EP12185155.4A patent/EP2540843B1/en active Active
- 2009-11-05 SI SI200931009T patent/SI2540843T1/sl unknown
- 2009-11-05 CN CN201310181349.5A patent/CN103333952B/zh not_active Expired - Fee Related
- 2009-11-05 JP JP2011534924A patent/JP5701216B2/ja not_active Expired - Fee Related
- 2009-11-05 MX MX2011004763A patent/MX2011004763A/es active IP Right Grant
- 2009-11-05 PL PL12185155T patent/PL2540843T3/pl unknown
- 2009-11-05 ES ES12185155.4T patent/ES2498274T3/es active Active
- 2009-11-05 KR KR1020117010284A patent/KR101719376B1/ko not_active Expired - Fee Related
- 2009-11-05 CN CN200980144066.5A patent/CN102203296B/zh not_active Expired - Fee Related
- 2009-11-05 AU AU2009313475A patent/AU2009313475B2/en not_active Ceased
- 2009-11-05 WO PCT/US2009/063434 patent/WO2010054110A2/en not_active Ceased
- 2009-11-05 US US13/127,433 patent/US20120003641A1/en not_active Abandoned
-
2011
- 2011-03-29 IL IL211995A patent/IL211995A/en active IP Right Grant
-
2016
- 2016-07-20 US US15/215,426 patent/US20170159114A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20110081836A (ko) | 2011-07-14 |
| EP2540843A3 (en) | 2013-05-29 |
| US20170159114A1 (en) | 2017-06-08 |
| MX2011004763A (es) | 2011-06-01 |
| WO2010054110A2 (en) | 2010-05-14 |
| EP2540843B1 (en) | 2014-07-02 |
| HK1173751A1 (en) | 2013-05-24 |
| EP2540843A2 (en) | 2013-01-02 |
| BRPI0914368A2 (pt) | 2015-10-20 |
| ES2498274T3 (es) | 2014-09-24 |
| JP2012507988A (ja) | 2012-04-05 |
| IL211995A0 (en) | 2011-06-30 |
| DK2540843T3 (da) | 2014-09-01 |
| IL211995A (en) | 2014-04-30 |
| PL2540843T3 (pl) | 2014-12-31 |
| CN102203296A (zh) | 2011-09-28 |
| CN103333952B (zh) | 2015-07-29 |
| US20120003641A1 (en) | 2012-01-05 |
| AU2009313475A1 (en) | 2010-05-14 |
| JP5701216B2 (ja) | 2015-04-15 |
| EP2356250A2 (en) | 2011-08-17 |
| CN102203296B (zh) | 2014-12-03 |
| KR101719376B1 (ko) | 2017-03-23 |
| SI2540843T1 (sl) | 2014-10-30 |
| WO2010054110A3 (en) | 2010-08-19 |
| CN103333952A (zh) | 2013-10-02 |
| AU2009313475B2 (en) | 2016-06-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2009313475B2 (en) | Genetic polymorphisms in age-related macular degeneration | |
| AU2010310804B2 (en) | Genetic polymorphisms in age-related macular degeneration | |
| AU2008334070A1 (en) | VEGF polymorphisms and anti-angiogenesis therapy | |
| EP1863931A2 (en) | Diagnostic and therapeutic target for macular degeneration | |
| HK1173751B (en) | Genetic polymorphisms in age-related macular degeneration | |
| CA2924277A1 (en) | Genotyping tests and methods for evaluating plasma creatine kinase levels | |
| HK1173192A (en) | Genetic polymorphisms in age-related macular degeneration | |
| HK1173192B (en) | Genetic polymorphisms in age-related macular degeneration | |
| BRPI0914368B1 (pt) | Método para predizer se um paciente com degeneração macular relacionada à idade (dmri) úmida tem uma maior probabilidade de se beneficiar pelo tratamento com um anticorpo anti-vegf e método para predizer se um indivíduo tem uma maior probabilidade de desenvolver dmri úmida ou dmri seca com atrofia geográfica (ag) | |
| JP2002085075A (ja) | 慢性関節リウマチ患者における続発性ａａ−アミロイドーシス罹患危険率の検出方法及びｓａａ１遺伝子座における一塩基多型を含む新規オリゴヌクレオチド |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20141028 |
|
| FZDE | Discontinued |
Effective date: 20210831 |