CA2734135C - Inhalateur de pmdi comprenant du fluticasone et du salmeterol - Google Patents

Inhalateur de pmdi comprenant du fluticasone et du salmeterol Download PDF

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Publication number
CA2734135C
CA2734135C CA2734135A CA2734135A CA2734135C CA 2734135 C CA2734135 C CA 2734135C CA 2734135 A CA2734135 A CA 2734135A CA 2734135 A CA2734135 A CA 2734135A CA 2734135 C CA2734135 C CA 2734135C
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CA
Canada
Prior art keywords
link
pmdi
flap
inhaler
container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2734135A
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English (en)
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CA2734135A1 (fr
Inventor
John Hywel Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cipla EU Ltd
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Cipla EU Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Application filed by Cipla EU Ltd filed Critical Cipla EU Ltd
Publication of CA2734135A1 publication Critical patent/CA2734135A1/fr
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0073—Mechanical counters having a display or indicator on a ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0075—Mechanical counters having a display or indicator on a disc
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008—Electronic counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Abstract

La présente invention porte sur des inhalateurs doseurs destinés à l'administration de médicaments actifs/propulseurs et excipients à partir de canettes d'aérosol sous pression. L'invention porte sur un inhalateur de pMDI (20) comprenant une canette de pMDI (22), un dispositif de tourbillon, un avertisseur sonore intégré (58) et un mécanisme activé par la respiration (26, 28, 34, 66, 78), la canette (22) contenant une formulation renfermant une combinaison de deux ingrédients actifs ou plus.
CA2734135A 2008-07-14 2009-07-14 Inhalateur de pmdi comprenant du fluticasone et du salmeterol Active CA2734135C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0812854.8A GB2461752B (en) 2008-07-14 2008-07-14 Metered dose inhaler
GB0812854.8 2008-07-14
PCT/GB2009/001740 WO2010007361A1 (fr) 2008-07-14 2009-07-14 Inhalateur doseur

Publications (2)

Publication Number Publication Date
CA2734135A1 CA2734135A1 (fr) 2010-01-21
CA2734135C true CA2734135C (fr) 2020-12-29

Family

ID=39722250

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2734135A Active CA2734135C (fr) 2008-07-14 2009-07-14 Inhalateur de pmdi comprenant du fluticasone et du salmeterol

Country Status (6)

Country Link
EP (1) EP2313113A1 (fr)
CA (1) CA2734135C (fr)
GB (1) GB2461752B (fr)
NZ (1) NZ591174A (fr)
WO (1) WO2010007361A1 (fr)
ZA (1) ZA201101206B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2394589T3 (es) 2007-12-14 2013-02-04 Aerodesigns, Inc Suministro de productos alimenticios transformables en aerosol
JP4878651B1 (ja) * 2010-09-17 2012-02-15 シャープ株式会社 移動局装置、通信システム、通信方法および集積回路
GB201118845D0 (en) 2011-11-01 2011-12-14 Euro Celtique Sa Dispenser
CA2914227C (fr) 2013-03-14 2019-11-12 Trudell Medical International Applicateur d'inhalateur doseur
EP3247339A1 (fr) * 2015-01-23 2017-11-29 Teva Branded Pharmaceutical Products R & D, Inc. Médicament inhalable
GB2544477A (en) * 2015-11-16 2017-05-24 3M Innovative Properties Co Improvements in or relating to medical actuators

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986001730A1 (fr) * 1984-09-18 1986-03-27 Vortran Corporation Dispositif de production d'aerosol
EP0308524B1 (fr) * 1987-09-22 1995-04-26 Vortran Medical Technology, Inc. Dispositif d'inhalation et méthode
US4955371A (en) * 1989-05-08 1990-09-11 Transtech Scientific, Inc. Disposable inhalation activated, aerosol device for pulmonary medicine
US6119688A (en) * 1991-08-26 2000-09-19 3M Innovative Properties Company Powder dispenser
IL106930A0 (en) * 1992-09-08 1993-12-28 Norton Healthcare Ltd Medicament dispensing device
MXPA02003784A (es) * 1999-10-16 2002-12-13 Glaxo Group Ltd Alojamiento de dispositivo para recipiente de aerosol.
US6581590B1 (en) * 2000-03-21 2003-06-24 Iep Pharmaceutical Devices Inc. Inhalation actuated device
AR028746A1 (es) * 2000-06-23 2003-05-21 Norton Health Care Ltd Cartucho de dosis previamente medidas para inhalador de polvo seco accionado por la respiracion, el inhalador y un metodo de provision de dosis previamente medidas de polvo seco
JP2005523905A (ja) * 2002-03-01 2005-08-11 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ ホルモテロール（ｆｏｒｍｏｔｅｒｏｌ）超微細調合物
SE0301426D0 (sv) * 2003-05-15 2003-05-15 Astrazeneca Ab Novel treatment
US7703454B2 (en) * 2003-07-14 2010-04-27 Vortran Medical Technology Inhaler with breath actuated dose counter
US7600512B2 (en) * 2003-07-14 2009-10-13 Vortran Medical Technology 1, Inc. Inhaler with breath actuated dose counter
US7219664B2 (en) * 2005-04-28 2007-05-22 Kos Life Sciences, Inc. Breath actuated inhaler
GB0518770D0 (en) * 2005-09-14 2005-10-26 Glaxo Group Ltd A closure for a dispensing device
AR058290A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Dispensador de medicamento
GB0602897D0 (en) * 2006-02-13 2006-03-22 Jagotec Ag Improvements In Or Relating To Dry Powder Inhaler Devices
GB0611131D0 (en) * 2006-06-06 2006-07-19 Neo Inhalation Technologies Lt Nicotine inhalation therapies - smoking cessation and other medical uses
CA2683724A1 (fr) * 2007-04-30 2009-01-15 Sun Pharma Advanced Research Company Limited Dispositif d'inhalation

Also Published As

Publication number Publication date
ZA201101206B (en) 2012-04-25
CA2734135A1 (fr) 2010-01-21
WO2010007361A1 (fr) 2010-01-21
GB2461752A (en) 2010-01-20
GB0812854D0 (en) 2008-08-20
EP2313113A1 (fr) 2011-04-27
NZ591174A (en) 2013-09-27
GB2461752B (en) 2013-04-17

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