CA2728736A1 - Compositions et procedes a base de microvesicules - Google Patents

Compositions et procedes a base de microvesicules Download PDF

Info

Publication number
CA2728736A1
CA2728736A1 CA2728736A CA2728736A CA2728736A1 CA 2728736 A1 CA2728736 A1 CA 2728736A1 CA 2728736 A CA2728736 A CA 2728736A CA 2728736 A CA2728736 A CA 2728736A CA 2728736 A1 CA2728736 A1 CA 2728736A1
Authority
CA
Canada
Prior art keywords
microvesicles
rna
cancer
rna molecules
condition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2728736A
Other languages
English (en)
Inventor
Zbigniew Pietrzkowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proxy Life Science Holdings Inc
Original Assignee
Proxy Life Science Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proxy Life Science Holdings Inc filed Critical Proxy Life Science Holdings Inc
Publication of CA2728736A1 publication Critical patent/CA2728736A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2728736A 2008-06-20 2009-06-19 Compositions et procedes a base de microvesicules Abandoned CA2728736A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7421808P 2008-06-20 2008-06-20
US61/074,218 2008-06-20
PCT/US2009/047937 WO2009155505A2 (fr) 2008-06-20 2009-06-19 Compositions et procédés à base de microvésicules

Publications (1)

Publication Number Publication Date
CA2728736A1 true CA2728736A1 (fr) 2009-12-23

Family

ID=40996611

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2728736A Abandoned CA2728736A1 (fr) 2008-06-20 2009-06-19 Compositions et procedes a base de microvesicules

Country Status (6)

Country Link
EP (1) EP2310529A2 (fr)
JP (1) JP2011525114A (fr)
CN (1) CN102105598A (fr)
AU (1) AU2009259893A1 (fr)
CA (1) CA2728736A1 (fr)
WO (1) WO2009155505A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009021322A1 (fr) 2007-08-16 2009-02-19 The Royal Institution For The Advancement Of Learning/Mcgill University Microvésicules issues d'une cellule tumorale
US20100255514A1 (en) 2007-08-16 2010-10-07 The Royal Institution For The Advancement Of Learning/Mcgill University Tumor cell-derived microvesicles
CA2742324A1 (fr) 2008-10-30 2010-06-03 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Procedes d'evaluation de motifs arn
BRPI0921043A2 (pt) * 2008-11-12 2018-08-07 Caris Life Sciences Luxembourg Holdings métodos e sistemas para usar exossomas para determinar fenótipos
WO2011031892A1 (fr) 2009-09-09 2011-03-17 The General Hospital Corporation Utilisation de microvésicules dans l'analyse de mutations kras
EP3461912B1 (fr) 2009-09-09 2022-07-13 The General Hospital Corporation Utilisation de microvésicules dans l'analyse de profils d'acides nucléiques
JP5808349B2 (ja) 2010-03-01 2015-11-10 カリス ライフ サイエンシズ スウィッツァーランド ホールディングスゲーエムベーハー セラノーシスのためのバイオマーカー
WO2011127219A1 (fr) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings Biomarqueurs circulants pour une maladie
EP3719502A1 (fr) * 2010-06-23 2020-10-07 University of Louisville Research Foundation, Inc. Procedes de detection de cancer
WO2012031008A2 (fr) * 2010-08-31 2012-03-08 The General Hospital Corporation Matières biologiques liées au cancer dans des microvésicules
US20130295574A1 (en) 2010-11-10 2013-11-07 Exosome Diagnostics, Inc. Method for Isolation of Nucleic Acid Containing Particles and Extraction of Nucleic Acids Therefrom
AU2012346594B2 (en) * 2011-11-30 2017-12-21 Agency For Science, Technology And Research GM1 ganglioside to Annexin V microparticle polypeptide ratio for biological monitoring
KR102067849B1 (ko) * 2012-05-11 2020-01-20 국립연구개발법인 고쿠리츠간켄큐센터 신장 세포암의 예후 예측방법
WO2014160032A1 (fr) * 2013-03-13 2014-10-02 University Of Louisville Research Foundation, Inc. Arn associé à un exosome en tant que marqueur de diagnostic
CN105755148B (zh) * 2016-04-29 2019-03-29 冯宾 一种检测骨关节炎的试剂盒及其方法
CN108977547B (zh) * 2018-08-14 2019-05-28 江门市中心医院 Tspan1在乳腺癌转移的诊断、预后及治疗中的应用
CN109596841B (zh) * 2019-01-14 2020-04-14 浙江大学 外泌体TβRII蛋白作为标志物在制备乳腺癌检测试剂盒中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69739909D1 (de) * 1996-03-26 2010-07-29 Michael S Kopreski Methoden aus plasma oder serum extrahierte extrazelluraere rna zur diagnoseüberwachung oder evaluation von krebs verwenden
GB9927320D0 (en) * 1999-11-18 2000-01-12 Chiron Spa Exosome separation
JP2008501336A (ja) * 2004-06-02 2008-01-24 ソースフアーム・インコーポレイテツド Ｒｎａを含有する微小胞およびそのための方法

Also Published As

Publication number Publication date
AU2009259893A1 (en) 2009-12-23
JP2011525114A (ja) 2011-09-15
EP2310529A2 (fr) 2011-04-20
CN102105598A (zh) 2011-06-22
WO2009155505A3 (fr) 2010-02-18
WO2009155505A2 (fr) 2009-12-23

Similar Documents

Publication Publication Date Title
US8021847B2 (en) Microvesicle-based compositions and methods
CA2728736A1 (fr) Compositions et procedes a base de microvesicules
JP6977014B2 (ja) 個別的エピゲノミクスのための天然クロマチンへの転移
van Eijndhoven et al. Plasma vesicle miRNAs for therapy response monitoring in Hodgkin lymphoma patients
Enderle et al. Characterization of RNA from exosomes and other extracellular vesicles isolated by a novel spin column-based method
US20220170021A1 (en) Oligonucleotide probes and uses thereof
AU2014305994B2 (en) Urine biomarker cohorts, gene expression signatures, and methods of use thereof
JP2021074011A (ja) 体液中の疾患または症状のシグネチャを検出する方法
JP2020126067A5 (fr)
US20170356903A1 (en) Oligonucleotide probes and uses thereof
EP3492606B1 (fr) Biomarqueurs urinaires
US20160041153A1 (en) Biomarker compositions and markers
US20150152474A1 (en) Biomarker compositions and methods
US20140220580A1 (en) Biomarker compositions and methods
BR112016004153A2 (pt) "método para caracterizar uma doença ou distúrbio, kit, composição, método para gerar uma biblioteca de entrada, oligonucleotídeo, pluralidade de oligonucleotídeos e método para identificar um aptâmero
KR20190020649A (ko) 역형성 림프종 키나아제(alk) 핵산 및 alk 융합 전사물의 혈장 기반 검출 및 암의 진단 및 치료에 있어 이의 용도
JP2016145835A (ja) 体液中における疾患または状態のシグネチャーを検出する方法
CA2892490A1 (fr) Compositions de biomarqueur et procedes
AU2012294458A1 (en) Biomarker compositions and methods
CA2838728A1 (fr) Biomarqueurs circulants pour le cancer
WO2012125721A2 (fr) Procédés et matériaux pour utiliser le contenu des phagocytes afin de détecter les néoplasmes
JP2020511933A (ja) 癌検出のための方法
WO2022034300A1 (fr) Analyse multiomique de couronnes de nanoparticules
Tesovnik et al. Technological approaches in the analysis of extracellular vesicle nucleotide sequences
Skryabin et al. Comparison of methods for MicroRNA isolation from extracellular vesicles obtained from ascitic fluids

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20140619