CA2726939A1 - 4,6-diphenylpyrid-2-ones against cancer - Google Patents
4,6-diphenylpyrid-2-ones against cancer Download PDFInfo
- Publication number
- CA2726939A1 CA2726939A1 CA2726939A CA2726939A CA2726939A1 CA 2726939 A1 CA2726939 A1 CA 2726939A1 CA 2726939 A CA2726939 A CA 2726939A CA 2726939 A CA2726939 A CA 2726939A CA 2726939 A1 CA2726939 A1 CA 2726939A1
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- lower alkyl
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP0810228.7 | 2008-06-04 | ||
| GBGB0810228.7A GB0810228D0 (en) | 2008-06-04 | 2008-06-04 | Novel compounds |
| PCT/EP2009/004005 WO2009146910A1 (en) | 2008-06-04 | 2009-06-04 | 4, 6-diphenylpyrid-2-0nes against cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2726939A1 true CA2726939A1 (en) | 2009-12-10 |
Family
ID=39638174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2726939A Abandoned CA2726939A1 (en) | 2008-06-04 | 2009-06-04 | 4,6-diphenylpyrid-2-ones against cancer |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8236827B2 (enExample) |
| EP (1) | EP2310370A1 (enExample) |
| JP (1) | JP2011521986A (enExample) |
| AU (1) | AU2009254176A1 (enExample) |
| CA (1) | CA2726939A1 (enExample) |
| GB (1) | GB0810228D0 (enExample) |
| WO (1) | WO2009146910A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130217594A1 (en) * | 2010-10-29 | 2013-08-22 | Institute for Cancer Research d/b/a The Research Center of Fox Chase Cancer (Fox Chase Cancer | Methods for screening compounds for capability to inhibit premalignant squamous epithelial cell progression to a malignant state |
| WO2012075136A2 (en) * | 2010-11-30 | 2012-06-07 | Fox Chase Cancer Center | Targeting of cyp1b1 in the treatment of head and neck cancer and lung cancer |
| CN103387574A (zh) * | 2012-05-07 | 2013-11-13 | 北京以岭药业有限公司 | 一种表小檗碱的合成方法 |
| CN107591180A (zh) * | 2016-07-07 | 2018-01-16 | 中芯国际集成电路制造(上海)有限公司 | 非挥发性存储器及其读取数据的方法 |
| JP7092742B2 (ja) * | 2016-07-13 | 2022-06-28 | セントレ ナシオナル デ ラ ルシェルシェ シエンティフィーク | ケモカインの生物活性を中和するためのピリミジノン誘導体およびその使用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0123777D0 (en) | 2001-10-03 | 2001-11-21 | Cancer Res Ventures Ltd | Substituted chalcones as therapeutic agents |
| US7910742B2 (en) | 2005-09-29 | 2011-03-22 | Abbott Laboratories | Survivin inhibitors |
| CA2685106A1 (en) * | 2007-04-25 | 2008-11-06 | Exelixis, Inc. | 6-phenylpyrimidinones as pim modulators |
-
2008
- 2008-06-04 GB GBGB0810228.7A patent/GB0810228D0/en not_active Ceased
-
2009
- 2009-06-04 EP EP09757293A patent/EP2310370A1/en not_active Withdrawn
- 2009-06-04 JP JP2011512021A patent/JP2011521986A/ja active Pending
- 2009-06-04 WO PCT/EP2009/004005 patent/WO2009146910A1/en not_active Ceased
- 2009-06-04 CA CA2726939A patent/CA2726939A1/en not_active Abandoned
- 2009-06-04 AU AU2009254176A patent/AU2009254176A1/en not_active Abandoned
- 2009-06-04 US US12/478,587 patent/US8236827B2/en not_active Expired - Fee Related
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2012
- 2012-07-25 US US13/557,508 patent/US20130023567A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009146910A1 (en) | 2009-12-10 |
| GB0810228D0 (en) | 2008-07-09 |
| US20130023567A1 (en) | 2013-01-24 |
| US20100168180A1 (en) | 2010-07-01 |
| JP2011521986A (ja) | 2011-07-28 |
| AU2009254176A1 (en) | 2009-12-10 |
| EP2310370A1 (en) | 2011-04-20 |
| WO2009146910A8 (en) | 2011-04-07 |
| US8236827B2 (en) | 2012-08-07 |
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| FZDE | Dead |
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