CA2723904C - Novel modulators of sphingosine phosphate receptors - Google Patents
Novel modulators of sphingosine phosphate receptors Download PDFInfo
- Publication number
- CA2723904C CA2723904C CA2723904A CA2723904A CA2723904C CA 2723904 C CA2723904 C CA 2723904C CA 2723904 A CA2723904 A CA 2723904A CA 2723904 A CA2723904 A CA 2723904A CA 2723904 C CA2723904 C CA 2723904C
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- Prior art keywords
- compound
- oet
- malcondition
- pharmaceutically acceptable
- alkyl
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- 229910019142 PO4 Inorganic materials 0.000 title description 11
- 239000010452 phosphate Substances 0.000 title description 11
- WWUZIQQURGPMPG-UHFFFAOYSA-N (-)-D-erythro-Sphingosine Natural products CCCCCCCCCCCCCC=CC(O)C(N)CO WWUZIQQURGPMPG-UHFFFAOYSA-N 0.000 title description 2
- WWUZIQQURGPMPG-KRWOKUGFSA-N sphingosine Chemical compound CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO WWUZIQQURGPMPG-KRWOKUGFSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract description 253
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| WO2015196258A1 (en) * | 2014-06-26 | 2015-12-30 | Monash University | Enzyme interacting agents |
| EP3470400A1 (en) | 2016-06-14 | 2019-04-17 | Crystal Pharmaceutical (Suzhou) Co., Ltd. | Crystal form of ozanimod, crystal form of hydrochloride thereof, and preparation method therefor |
| CN109563059A (zh) | 2016-08-19 | 2019-04-02 | 苏州科睿思制药有限公司 | 奥扎莫德的晶型及其制备方法 |
| CN109640982A (zh) | 2016-09-14 | 2019-04-16 | 苏州科睿思制药有限公司 | 奥扎莫德盐酸盐的晶型及其制备方法 |
| CN108137516A (zh) | 2016-09-14 | 2018-06-08 | 杭州领业医药科技有限公司 | 奥扎莫德的晶型、其制备方法及药物组合物 |
| CN106749213B (zh) * | 2016-11-25 | 2019-07-02 | 济南大学 | 一种具有1,2,4-恶二唑结构的吲哚衍生物及制备方法和在制备抗菌药物中的应用 |
| WO2019042219A1 (zh) | 2017-08-31 | 2019-03-07 | 苏州科睿思制药有限公司 | 奥扎莫德盐酸盐的晶型及其制备方法 |
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| CA2648303C (en) * | 2006-04-03 | 2014-07-15 | Astellas Pharma Inc. | 5-[monocyclic(hetero)arylsubstituted-1,2,4-oxadliazol-3-yl]-(fused heteroaryl substituted) compounds and their use as s1p1 agonists |
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| BRPI0912545B1 (pt) | 2022-02-01 |
| LT2913326T (lt) | 2020-09-10 |
| CN102118972B (zh) | 2015-06-10 |
| IL209306A0 (en) | 2011-01-31 |
| BRPI0912545A2 (pt) | 2021-04-13 |
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| ZA201007804B (en) | 2012-01-25 |
| KR20150064245A (ko) | 2015-06-10 |
| MX2010012461A (es) | 2013-07-02 |
| SI2913326T1 (sl) | 2020-11-30 |
| IL209306A (he) | 2017-02-28 |
| CN102118972A (zh) | 2011-07-06 |
| HRP20201316T1 (hr) | 2020-11-27 |
| CA2723904A1 (en) | 2009-12-17 |
| DK2913326T3 (da) | 2020-08-17 |
| HUE050411T2 (hu) | 2020-12-28 |
| KR101582910B1 (ko) | 2016-01-08 |
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