CA2718634A1 - Anticorps diriges contre des cytokines du type interleukine-10 et leurs utilisations - Google Patents

Anticorps diriges contre des cytokines du type interleukine-10 et leurs utilisations Download PDF

Info

Publication number
CA2718634A1
CA2718634A1 CA2718634A CA2718634A CA2718634A1 CA 2718634 A1 CA2718634 A1 CA 2718634A1 CA 2718634 A CA2718634 A CA 2718634A CA 2718634 A CA2718634 A CA 2718634A CA 2718634 A1 CA2718634 A1 CA 2718634A1
Authority
CA
Canada
Prior art keywords
mutant
amino acid
alanine
polypeptide
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2718634A
Other languages
English (en)
Inventor
Lynette A. Fouser
Jing Li
Paul W. Wu
Sreekumar R. Kodangattli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of CA2718634A1 publication Critical patent/CA2718634A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2718634A 2008-03-21 2009-03-20 Anticorps diriges contre des cytokines du type interleukine-10 et leurs utilisations Abandoned CA2718634A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6471808P 2008-03-21 2008-03-21
US61/064,718 2008-03-21
PCT/US2009/037773 WO2009117640A2 (fr) 2008-03-21 2009-03-20 Anticorps dirigés contre des cytokines du type interleukine-10 et leurs utilisations

Publications (1)

Publication Number Publication Date
CA2718634A1 true CA2718634A1 (fr) 2009-09-24

Family

ID=40852583

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2718634A Abandoned CA2718634A1 (fr) 2008-03-21 2009-03-20 Anticorps diriges contre des cytokines du type interleukine-10 et leurs utilisations

Country Status (2)

Country Link
CA (1) CA2718634A1 (fr)
WO (1) WO2009117640A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103182072B (zh) * 2011-12-27 2017-05-03 健能隆医药技术(上海)有限公司 白介素‑22在治疗和预防神经损伤疾病或神经退行性疾病中的用途
SG11201507429TA (en) 2013-03-15 2015-10-29 Genentech Inc Il-22 polypeptides and il-22 fc fusion proteins and methods of use
CN109425450B (zh) * 2017-08-23 2021-04-23 北京纳米能源与系统研究所 传感器及应用其的电子、仿生皮肤及仿生交流通讯设备

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020187512A1 (en) * 2001-09-10 2002-12-12 Nagem Ronaldo Alves Pinto Crystal structure of human interleukin-22
KR20060022289A (ko) * 2003-06-23 2006-03-09 제네틱스 인스티튜트, 엘엘씨 인터류킨-22 에 대한 항체 및 그의 용도
TW200744634A (en) * 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22

Also Published As

Publication number Publication date
WO2009117640A2 (fr) 2009-09-24
WO2009117640A3 (fr) 2009-12-10

Similar Documents

Publication Publication Date Title
Luo et al. Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab
CN102782148B (zh) 与多种cc趋化因子结合的抗因子抗体
AU2002213053B2 (en) Nectin polypeptides, polynucleotides, methods of making and use thereof
EP1644415B1 (fr) Anticorps contre l'interleukine-22 et utilisations
Gerhardt et al. Structure of IL-17A in complex with a potent, fully human neutralizing antibody
JP2008029349A (ja) ヘマトポエチン受容体、hpr1およびhpr2
AU2019276486A1 (en) Anti-interleukin-17A antibody, pharmaceutical composition thereof and use thereof
AU2002213053A1 (en) Nectin polypeptides, polynucleotides, methods of making and use thereof
Wu et al. IL-22R, IL-10R2, and IL-22BP binding sites are topologically juxtaposed on adjacent and overlapping surfaces of IL-22
AU2001284977B2 (en) Claudin polypeptides
CN101103044A (zh) 抗α9整联蛋白抗体及其用途
Lennartz et al. Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding
AU2002223182A1 (en) Hematopoietin receptors HPR1 and HPR2
JP2009132715A (ja) 新規クラスiiサイトカイン受容体およびその使用
AU2002314774B2 (en) Cytokine polypeptides
CA2718634A1 (fr) Anticorps diriges contre des cytokines du type interleukine-10 et leurs utilisations
Dhagat et al. The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities
AU2002314774A1 (en) Cytokine polypeptides
US20180141994A1 (en) Toll-like receptor 2 binding epitope and binding member thereto
US7186802B2 (en) Claudin polypeptides
Yao et al. Identification of core functional region of murine IL-4 using peptide phage display and molecular modeling
AU2007237257A1 (en) Hematopoietin receptors HPR1 and HPR2
JP2005514916A (ja) ヒトおよびネズミサイトカインポリペプチド

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead