CA2712269A1 - Selective subtype alpha 2 adrenergic agents and methods for use thereof - Google Patents

Selective subtype alpha 2 adrenergic agents and methods for use thereof Download PDF

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Publication number
CA2712269A1
CA2712269A1 CA2712269A CA2712269A CA2712269A1 CA 2712269 A1 CA2712269 A1 CA 2712269A1 CA 2712269 A CA2712269 A CA 2712269A CA 2712269 A CA2712269 A CA 2712269A CA 2712269 A1 CA2712269 A1 CA 2712269A1
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Canada
Prior art keywords
compound
independently
alpha
pain
lower alkyl
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Abandoned
Application number
CA2712269A
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English (en)
French (fr)
Inventor
Todd M. Heidelbaugh
Ken Chow
Santosh C. Sinha
Phong X. Nguyen
Wenkui K. Fang
Ling Li
Janet A. Takeuchi
Smita S. Bhat
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Allergan Inc
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Individual
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Publication of CA2712269A1 publication Critical patent/CA2712269A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • AIDS & HIV (AREA)
CA2712269A 2008-01-18 2009-01-15 Selective subtype alpha 2 adrenergic agents and methods for use thereof Abandoned CA2712269A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2214208P 2008-01-18 2008-01-18
US61/022,142 2008-01-18
US12/353,406 2009-01-14
US12/353,406 US8809379B2 (en) 2008-01-18 2009-01-14 Selective subtype alpha 2 adrenergic agents and methods for use thereof
PCT/US2009/031077 WO2009091874A1 (en) 2008-01-18 2009-01-15 Selective subtype alpha 2 adrenergic agents and methods for use thereof

Publications (1)

Publication Number Publication Date
CA2712269A1 true CA2712269A1 (en) 2009-07-23

Family

ID=40383664

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2712269A Abandoned CA2712269A1 (en) 2008-01-18 2009-01-15 Selective subtype alpha 2 adrenergic agents and methods for use thereof

Country Status (7)

Country Link
US (1) US8809379B2 (https=)
EP (1) EP2249834B1 (https=)
JP (1) JP2011510013A (https=)
AU (1) AU2009206137B2 (https=)
BR (1) BRPI0906928A8 (https=)
CA (1) CA2712269A1 (https=)
WO (1) WO2009091874A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2242753B1 (en) * 2008-01-18 2015-04-08 Allergan, Inc. Oxazolidine and thiazolidine selective subtype alpha 2 adrenergic agents and methods for use thereof
HUE038366T2 (hu) * 2010-08-16 2018-10-29 Allergan Inc Módszer szabályozó T-sejtek alfa-2B adrenerg receptor agonistákkal való aktiválásához

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5212176A (en) 1990-06-29 1993-05-18 Abbott Laboratories R(+)-terazosin
KR100639473B1 (ko) * 2005-06-16 2006-10-27 주식회사 삼화양행 압전체의 온도 변화에 따른 주파수 특성을 비선형적으로구하는 방법
CN101346374A (zh) 2005-12-22 2009-01-14 巴斯夫欧洲公司 农业组合物
US7709507B2 (en) 2006-05-17 2010-05-04 Allergan, Inc. Therapeutic fluoroethyl ureas
WO2008123821A1 (en) 2007-03-01 2008-10-16 Albireo Ab 4, 5-dihydro-lh-imidazol-2-amine derivatives for use in the treatment of respiratory, cardiovascular, neurological or gastrointestinal disorders
WO2008115141A1 (en) 2007-03-19 2008-09-25 Albireo Ab 4, 5-dihydro-1,3-thiazol-2-amine derivatives and their use in the treatment of respiratory, cardiovascular, neurological or gastrointestinal disorders
EP2242753B1 (en) * 2008-01-18 2015-04-08 Allergan, Inc. Oxazolidine and thiazolidine selective subtype alpha 2 adrenergic agents and methods for use thereof
JP5480819B2 (ja) * 2008-01-18 2014-04-23 アラーガン インコーポレイテッド 選択的サブタイプアルファ2アドレナリンアゴニスト及びその使用方法

Also Published As

Publication number Publication date
AU2009206137A1 (en) 2009-07-23
BRPI0906928A8 (pt) 2018-12-11
US8809379B2 (en) 2014-08-19
AU2009206137B2 (en) 2014-03-27
US20090197898A1 (en) 2009-08-06
EP2249834A1 (en) 2010-11-17
WO2009091874A1 (en) 2009-07-23
BRPI0906928A2 (pt) 2017-06-13
EP2249834B1 (en) 2015-05-13
JP2011510013A (ja) 2011-03-31

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