CA2710598A1 - Synthese d'iodixanol dans l'eau - Google Patents

Synthese d'iodixanol dans l'eau Download PDF

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Publication number
CA2710598A1
CA2710598A1 CA 2710598 CA2710598A CA2710598A1 CA 2710598 A1 CA2710598 A1 CA 2710598A1 CA 2710598 CA2710598 CA 2710598 CA 2710598 A CA2710598 A CA 2710598A CA 2710598 A1 CA2710598 A1 CA 2710598A1
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CA
Canada
Prior art keywords
bis
iodixanol
acetamido
dimerisation
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2710598
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English (en)
Other versions
CA2710598C (fr
Inventor
Geir Brekke
Otto Rogne
Trond Kjernli
Terje Svendsen
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GE Healthcare AS
Original Assignee
GE Healthcare AS
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Filing date
Publication date
Priority claimed from US12/621,675 external-priority patent/US20110021832A1/en
Application filed by GE Healthcare AS filed Critical GE Healthcare AS
Publication of CA2710598A1 publication Critical patent/CA2710598A1/fr
Application granted granted Critical
Publication of CA2710598C publication Critical patent/CA2710598C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

La présente invention concerne la synthèse diodixanol(1,3-bis(acétamido)-N,N- bis[3,5-bis(2,3- dihydroxypropylaminocarbonyl)-2,4,6-triiodophényl]-2-hydroxypropane), plus particulièrement la dimérisation du 5-acétamido-N,N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-isophtalamide avec leau comme solvant.
CA2710598A 2009-07-21 2010-07-20 Synthese d'iodixanol dans l'eau Active CA2710598C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22709409P 2009-07-21 2009-07-21
US61/227,094 2009-07-21
US12/621,675 2009-11-19
US12/621,675 US20110021832A1 (en) 2009-07-21 2009-11-19 Synthesis of iodixanol in water

Publications (2)

Publication Number Publication Date
CA2710598A1 true CA2710598A1 (fr) 2011-01-21
CA2710598C CA2710598C (fr) 2016-08-30

Family

ID=43495954

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2710598A Active CA2710598C (fr) 2009-07-21 2010-07-20 Synthese d'iodixanol dans l'eau

Country Status (1)

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CA (1) CA2710598C (fr)

Also Published As

Publication number Publication date
CA2710598C (fr) 2016-08-30

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Effective date: 20150708