CA2710577C - Cristallisation d'iodixanol par broyage - Google Patents

Cristallisation d'iodixanol par broyage Download PDF

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Publication number
CA2710577C
CA2710577C CA2710577A CA2710577A CA2710577C CA 2710577 C CA2710577 C CA 2710577C CA 2710577 A CA2710577 A CA 2710577A CA 2710577 A CA2710577 A CA 2710577A CA 2710577 C CA2710577 C CA 2710577C
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Canada
Prior art keywords
iodixanol
crystallization
product
compound
purification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2710577A
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English (en)
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CA2710577A1 (fr
Inventor
Khalid Hussain
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GE Healthcare AS
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GE Healthcare AS
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Publication date
Priority claimed from US12/611,956 external-priority patent/US7999134B2/en
Application filed by GE Healthcare AS filed Critical GE Healthcare AS
Publication of CA2710577A1 publication Critical patent/CA2710577A1/fr
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Publication of CA2710577C publication Critical patent/CA2710577C/fr
Active legal-status Critical Current
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Cette invention a trait à la fabrication de (1,3-bis(acétamido)- N,N'-bis¬3,5- bis(2,3-dihydroxypropylaminocarbonyl)-2,4,6-triiodophényl|-2-hydroxypropane)iodixanol, plus précisément à la purification de l'iodixanol par cristallisation par broyage humide.
CA2710577A 2009-07-21 2010-07-20 Cristallisation d'iodixanol par broyage Active CA2710577C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22710609P 2009-07-21 2009-07-21
US61/227,106 2009-07-21
US12/611,956 2009-11-04
US12/611,956 US7999134B2 (en) 2009-07-21 2009-11-04 Crystallization of iodixanol using milling

Publications (2)

Publication Number Publication Date
CA2710577A1 CA2710577A1 (fr) 2011-01-21
CA2710577C true CA2710577C (fr) 2012-09-18

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ID=43495950

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2710577A Active CA2710577C (fr) 2009-07-21 2010-07-20 Cristallisation d'iodixanol par broyage

Country Status (1)

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CA (1) CA2710577C (fr)

Also Published As

Publication number Publication date
CA2710577A1 (fr) 2011-01-21

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