CA2710398A1 - Methods and compositions for targeting polyubiquitin - Google Patents
Methods and compositions for targeting polyubiquitin Download PDFInfo
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- CA2710398A1 CA2710398A1 CA2710398A CA2710398A CA2710398A1 CA 2710398 A1 CA2710398 A1 CA 2710398A1 CA 2710398 A CA2710398 A CA 2710398A CA 2710398 A CA2710398 A CA 2710398A CA 2710398 A1 CA2710398 A1 CA 2710398A1
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| JP3196085B2 (ja) | 1992-03-16 | 2001-08-06 | 株式会社ケーヒン | 多連気化器の燃料増量装置 |
| RU2008128134A (ru) | 2005-12-15 | 2010-01-20 | Дженентек, Инк. (Us) | Способы и композиции для получения направленности на полиубиквитин |
| JP5523345B2 (ja) | 2008-01-18 | 2014-06-18 | ジェネンテック， インコーポレイテッド | Ｋ６３結合型ポリユビキチンを標的とする方法と組成物 |
| US20110053198A1 (en) * | 2009-08-25 | 2011-03-03 | Quest Diagnostics Investments Incorporated | Ubiquitin proteasome system profiling and the use thereof in clinical applications for proliferative hematological disorders |
| US20110053199A1 (en) * | 2009-08-25 | 2011-03-03 | Quest Diagnostics Investments Incorporated | Ubiquitin proteasome system profiling and the use thereof in clinical applications for cancer diagnosis |
| US20110053197A1 (en) * | 2009-08-25 | 2011-03-03 | Quest Diagnostics Investments Incorporated | Ubiquitin proteasome system profiling and the use thereof in clinical applications for cancer diagnosis |
| WO2011069009A1 (en) * | 2009-12-04 | 2011-06-09 | Quest Diagnostics Investments Incorporated | Polyubiquitin levels as a prognostic indicator in leukemia |
| CN102947335B (zh) | 2010-04-15 | 2018-11-06 | 基因泰克公司 | 抗多聚遍在蛋白抗体及使用方法 |
| WO2012089814A1 (en) * | 2010-12-30 | 2012-07-05 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antigen binding formats for use in therapeutic treatments or diagnostic assays |
| EP2739651B1 (en) | 2011-08-05 | 2019-02-20 | Genentech, Inc. | Anti-polyubiquitin antibodies and methods of use |
| CN107106689A (zh) | 2014-11-05 | 2017-08-29 | 沃雅戈治疗公司 | 用于治疗帕金森病的aadc多核苷酸 |
| KR102584655B1 (ko) | 2014-11-14 | 2023-10-06 | 보이저 테라퓨틱스, 인크. | 조절성 폴리뉴클레오티드 |
| MX2017006216A (es) | 2014-11-14 | 2018-08-29 | Voyager Therapeutics Inc | Composiciones y métodos para tratar la esclerosis lateral amiotrófica (ela). |
| US11326182B2 (en) | 2016-04-29 | 2022-05-10 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| WO2017189964A2 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| RU2758488C2 (ru) | 2016-05-18 | 2021-10-28 | Вояджер Терапьютикс, Инк. | Модулирующие полинуклеотиды |
| CN109563160B (zh) | 2016-06-24 | 2023-02-28 | 豪夫迈·罗氏有限公司 | 抗聚泛素多特异性抗体 |
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| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| ES3032734T3 (en) | 2017-10-27 | 2025-07-24 | Univ New York | Anti-galectin-9 antibodies and uses thereof |
| MX2020012077A (es) | 2018-05-15 | 2021-03-09 | Voyager Therapeutics Inc | Composiciones y metodos para el tratamiento de la enfermedad de parkinson. |
| US20220204629A1 (en) * | 2019-03-25 | 2022-06-30 | New York University | Anti-galectin-9 antibodies and uses thereof |
| WO2020223702A1 (en) * | 2019-05-01 | 2020-11-05 | New York University | Anti-galectin-9 antibodies and uses thereof |
| US20230277553A1 (en) * | 2020-08-07 | 2023-09-07 | Cornell University | Therapeutic composition of cure-pro compounds for targeted degradation of bet domain proteins, and methods of making and usage |
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| US20050106667A1 (en) | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
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| CN103212071B (zh) | 2005-08-25 | 2017-12-12 | 亚利桑那大学董事会 | 干细胞融合癌发生模型 |
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| EP1808493A3 (en) * | 2006-01-13 | 2007-11-21 | Hybrigenics S.A. | Substrates and methods for assaying deubiquitinating enzymes activity |
| WO2008121813A2 (en) | 2007-03-30 | 2008-10-09 | Genentech, Inc. | Modulation of cytokine production |
| JP5523345B2 (ja) | 2008-01-18 | 2014-06-18 | ジェネンテック， インコーポレイテッド | Ｋ６３結合型ポリユビキチンを標的とする方法と組成物 |
| CN102947335B (zh) | 2010-04-15 | 2018-11-06 | 基因泰克公司 | 抗多聚遍在蛋白抗体及使用方法 |
| EP2739651B1 (en) | 2011-08-05 | 2019-02-20 | Genentech, Inc. | Anti-polyubiquitin antibodies and methods of use |
| WO2018067198A1 (en) * | 2016-10-03 | 2018-04-12 | The Regents Of The University Of California | Inhibitory antibodies and methods of use thereof |
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| US20160009791A1 (en) | 2016-01-14 |
| US20210115120A1 (en) | 2021-04-22 |
| US9081015B2 (en) | 2015-07-14 |
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| US20160355577A1 (en) | 2016-12-08 |
| US10035849B2 (en) | 2018-07-31 |
| US20120135008A1 (en) | 2012-05-31 |
| WO2009126350A3 (en) | 2009-12-03 |
| ES2414804T3 (es) | 2013-07-22 |
| US20190023774A1 (en) | 2019-01-24 |
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