CA2707156A1 - Systemes de prevision de l'agregation de proteines - Google Patents

Systemes de prevision de l'agregation de proteines Download PDF

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Publication number
CA2707156A1
CA2707156A1 CA2707156A CA2707156A CA2707156A1 CA 2707156 A1 CA2707156 A1 CA 2707156A1 CA 2707156 A CA2707156 A CA 2707156A CA 2707156 A CA2707156 A CA 2707156A CA 2707156 A1 CA2707156 A1 CA 2707156A1
Authority
CA
Canada
Prior art keywords
aggregation
amino acid
propensity
protein
value
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2707156A
Other languages
English (en)
Inventor
Christopher Dobson
Sebastian Pechmann
Gian Gaetano Tartaglia
Michele Vendruscolo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cambridge Enterprise Ltd
Original Assignee
Cambridge Enterprise Limited
Christopher Dobson
Sebastian Pechmann
Gian Gaetano Tartaglia
Michele Vendruscolo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Enterprise Limited, Christopher Dobson, Sebastian Pechmann, Gian Gaetano Tartaglia, Michele Vendruscolo filed Critical Cambridge Enterprise Limited
Publication of CA2707156A1 publication Critical patent/CA2707156A1/fr
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
CA2707156A 2007-11-28 2008-11-13 Systemes de prevision de l'agregation de proteines Abandoned CA2707156A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0723288A GB2455102A (en) 2007-11-28 2007-11-28 Protein Aggregation Prediction Systems
GB0723288.7 2007-11-28
PCT/GB2008/051055 WO2009068900A2 (fr) 2007-11-28 2008-11-13 Systèmes de prévision de l'agrégation de protéines

Publications (1)

Publication Number Publication Date
CA2707156A1 true CA2707156A1 (fr) 2009-06-04

Family

ID=38962253

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2707156A Abandoned CA2707156A1 (fr) 2007-11-28 2008-11-13 Systemes de prevision de l'agregation de proteines

Country Status (11)

Country Link
US (1) US20110035155A1 (fr)
EP (1) EP2215576A2 (fr)
JP (1) JP5683959B2 (fr)
KR (1) KR20100110798A (fr)
CN (1) CN101925902A (fr)
AU (1) AU2008331323A1 (fr)
CA (1) CA2707156A1 (fr)
EA (1) EA201070654A1 (fr)
GB (1) GB2455102A (fr)
IL (1) IL206048A0 (fr)
WO (1) WO2009068900A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8669418B2 (en) 2005-12-22 2014-03-11 Vib Vzw Means and methods for mediating protein interference
GB201310859D0 (en) * 2013-06-18 2013-07-31 Cambridge Entpr Ltd Rational method for solubilising proteins
GB201409145D0 (en) * 2014-05-22 2014-07-09 Univ Strathclyde Stable emulsions
GB201600176D0 (en) * 2016-01-06 2016-02-17 Cambridge Entpr Ltd Method of identifying novel protein aggregation inhibitors based on chemical kinetics
KR101975639B1 (ko) * 2016-09-06 2019-05-07 숙명여자대학교산학협력단 단백질 응집가능성 예측방법
US11872262B2 (en) 2017-05-09 2024-01-16 Vib Vzw Means and methods for treating bacterial infections
CN108647489B (zh) * 2018-05-15 2020-06-30 华中农业大学 一种筛选疾病药物靶标和靶标组合的方法及系统
US11512345B1 (en) * 2021-05-07 2022-11-29 Peptilogics, Inc. Methods and apparatuses for generating peptides by synthesizing a portion of a design space to identify peptides having non-canonical amino acids
US11587643B2 (en) 2021-05-07 2023-02-21 Peptilogics, Inc. Methods and apparatuses for a unified artificial intelligence platform to synthesize diverse sets of peptides and peptidomimetics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3588605B2 (ja) * 2000-03-10 2004-11-17 第一製薬株式会社 蛋白質間相互作用予測方法
US20030032065A1 (en) * 2001-03-12 2003-02-13 Vince Hilser Ensemble-based strategy for the design of protein pharmaceuticals
DE602004025669D1 (de) * 2003-01-20 2010-04-08 Cambridge Entpr Ltd Rechnerisches verfahren und vorrichtung zur vorhersage der polypeptidaggregation oder lösbarkeit
GB0325817D0 (en) * 2003-11-05 2003-12-10 Univ Cambridge Tech Method and apparatus for assessing polypeptide aggregation
US7805252B2 (en) * 2005-08-16 2010-09-28 Dna Twopointo, Inc. Systems and methods for designing and ordering polynucleotides
SG173405A1 (en) * 2006-08-04 2011-08-29 Lonza Biologics Plc Method for predicting protein aggregation and designing aggregation inhibitors

Also Published As

Publication number Publication date
JP2011505044A (ja) 2011-02-17
IL206048A0 (en) 2010-11-30
CN101925902A (zh) 2010-12-22
GB0723288D0 (en) 2008-01-09
WO2009068900A2 (fr) 2009-06-04
EP2215576A2 (fr) 2010-08-11
JP5683959B2 (ja) 2015-03-11
US20110035155A1 (en) 2011-02-10
EA201070654A1 (ru) 2010-12-30
KR20100110798A (ko) 2010-10-13
AU2008331323A1 (en) 2009-06-04
GB2455102A (en) 2009-06-03
WO2009068900A3 (fr) 2009-09-24

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20141113