CA2697990A1 - Medication combinations for the treatment of alcoholism and drug addiction - Google Patents

Medication combinations for the treatment of alcoholism and drug addiction Download PDF

Info

Publication number
CA2697990A1
CA2697990A1 CA2697990A CA2697990A CA2697990A1 CA 2697990 A1 CA2697990 A1 CA 2697990A1 CA 2697990 A CA2697990 A CA 2697990A CA 2697990 A CA2697990 A CA 2697990A CA 2697990 A1 CA2697990 A1 CA 2697990A1
Authority
CA
Canada
Prior art keywords
administered
antagonists
compounds
alcohol
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2697990A
Other languages
English (en)
French (fr)
Inventor
Bankole A. Johnson
Nassima Ait-Daoud Tiouririne
Wendy J. Lynch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UVA Licensing and Ventures Group
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2697990A1 publication Critical patent/CA2697990A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2697990A 2007-08-27 2008-05-20 Medication combinations for the treatment of alcoholism and drug addiction Abandoned CA2697990A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96626507P 2007-08-27 2007-08-27
US60/966,265 2007-08-27
PCT/US2008/064232 WO2009029308A1 (en) 2007-08-27 2008-05-20 Medication combinations for the treatment of alcoholism and drug addiction

Publications (1)

Publication Number Publication Date
CA2697990A1 true CA2697990A1 (en) 2009-03-05

Family

ID=40387675

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2697990A Abandoned CA2697990A1 (en) 2007-08-27 2008-05-20 Medication combinations for the treatment of alcoholism and drug addiction

Country Status (4)

Country Link
US (1) US20110065628A1 (https=)
JP (1) JP2010537990A (https=)
CA (1) CA2697990A1 (https=)
WO (1) WO2009029308A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2436573C2 (ru) * 2009-07-27 2011-12-20 Учреждение Российской академии медицинских наук Научно-исследовательский институт психического здоровья Сибирского отделения Российской академии медицинских наук (НИИПЗ СО РАМН) Способ реабилитации больных алкоголизмом

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU764453B2 (en) 1999-10-29 2003-08-21 Euro-Celtique S.A. Controlled release hydrocodone formulations
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
MXPA03003895A (es) 2000-10-30 2003-07-28 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada.
US8030002B2 (en) 2000-11-16 2011-10-04 Curemark Llc Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions
US20080058282A1 (en) 2005-08-30 2008-03-06 Fallon Joan M Use of lactulose in the treatment of autism
JP2010513569A (ja) * 2006-12-19 2010-04-30 ユニバーシティ オブ バージニア パテント ファウンデーション アルコール摂取に対するトピラメートおよびオンダンセトロンの併用効果
CA2677205A1 (en) * 2007-01-31 2008-08-07 University Of Virginia Patent Foundation Topiramate plus naltrexone for the treatment of addictive disorders
WO2008095221A1 (en) 2007-02-07 2008-08-14 Gosforth Centre (Holdings) Pty Ltd Treatment of adhd
MX2010009509A (es) 2008-02-28 2010-11-30 Univ Virginia Gen transportador de serotonina y tratamiento de alcoholismo.
US8658163B2 (en) 2008-03-13 2014-02-25 Curemark Llc Compositions and use thereof for treating symptoms of preeclampsia
US8084025B2 (en) 2008-04-18 2011-12-27 Curemark Llc Method for the treatment of the symptoms of drug and alcohol addiction
US9320780B2 (en) 2008-06-26 2016-04-26 Curemark Llc Methods and compositions for the treatment of symptoms of Williams Syndrome
PL2318035T3 (pl) 2008-07-01 2019-10-31 Curemark Llc Sposoby i kompozycje do leczenia objawów zaburzeń neurologicznych i zaburzeń zdrowia psychicznego
US10776453B2 (en) 2008-08-04 2020-09-15 Galenagen, Llc Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain
EP2331088A4 (en) 2008-08-06 2011-10-12 Gosforth Ct Holdings Pty Ltd COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC ILLNESSES
US20100092447A1 (en) 2008-10-03 2010-04-15 Fallon Joan M Methods and compositions for the treatment of symptoms of prion diseases
CN102300989B (zh) 2009-01-06 2015-12-09 柯尔朗恩有限责任公司 用于治疗或预防金黄色葡萄球菌感染以及用于根除或减少表面上金黄色葡萄球菌的组合物和方法
KR20170005191A (ko) 2009-01-06 2017-01-11 큐어론 엘엘씨 이. 콜라이에 의한 구강 감염의 치료 또는 예방을 위한 조성물 및 방법
US20100196436A1 (en) * 2009-01-30 2010-08-05 Gooberman Lance L Implants containing disulfiram and an anti-inflammatory agent
US8791093B2 (en) * 2009-05-29 2014-07-29 Lance L. Gooberman Pharmaceutical delivery systems for treatment of substance abuse and other addictions
RU2402352C1 (ru) * 2009-08-13 2010-10-27 Государственное образовательное учреждение высшего профессионального образования "Российский университет дружбы народов" (РУДН) Способ угнетения алкогольной мотивации
US9511125B2 (en) 2009-10-21 2016-12-06 Curemark Llc Methods and compositions for the treatment of influenza
EA024450B1 (ru) 2010-07-02 2016-09-30 Юниверсити Оф Вирджиния Пэтент Фаундейшн Молекулярно-генетический подход к лечению и диагностике алкогольной и наркотической зависимости
US8980252B2 (en) 2011-04-21 2015-03-17 Curemark Llc Methods of treatment of schizophrenia
EP2751137A4 (en) * 2011-09-09 2015-06-03 Univ Virginia Patent Found MOLECULAR GENETIC APPROACH FOR THE TREATMENT AND DIAGNOSIS OF ALCOHOL AND DRUG INDEPENDENCE
RU2476209C1 (ru) * 2012-02-29 2013-02-27 Станислав Анатольевич Кедик Имплантируемое лекарственное средство на основе налтрексона для лечения пациентов, зависимых от алкоголя или опиатов
US10350278B2 (en) 2012-05-30 2019-07-16 Curemark, Llc Methods of treating Celiac disease
RU2495679C1 (ru) * 2012-07-16 2013-10-20 Станислав Анатольевич Кедик Имплант на основе дисульфирама для лечения пациентов, зависимых от алкоголя или опиатов
US10322120B2 (en) 2012-07-31 2019-06-18 Persion Pharmaceuticals Llc Treating pain in patients with hepatic impairment
US20140161879A1 (en) * 2012-07-31 2014-06-12 Zogenix, Inc. Treating pain in patients with hepatic impairment
WO2014120936A2 (en) * 2013-01-30 2014-08-07 Pharmorx Therapeutics, Inc. Treatments for depression and other diseases with a low dose agent
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
US9192570B2 (en) 2013-12-20 2015-11-24 AntiOP, Inc. Intranasal naloxone compositions and methods of making and using same
US10420756B2 (en) 2015-03-26 2019-09-24 Sen-Jam Pharmaceutical Llc. Methods and compositions to inhibit symptoms associated with veisalgia
WO2016160715A1 (en) * 2015-03-27 2016-10-06 Markel Dan Method for treating addiction
KR102453781B1 (ko) * 2016-06-24 2022-10-12 오피언트 파마슈티컬스, 인코퍼레이티드 알코올 사용 장애의 치료용 조성물, 장치 및 방법
RU2629529C1 (ru) * 2016-08-09 2017-08-29 Ольга Ивановна Салмина-Хвостова Способ лечения алкоголизма
RU2629530C1 (ru) * 2016-08-12 2017-08-29 Ольга Ивановна Салмина-Хвостова Способ лечения алкогольной зависимости
CN110139651A (zh) 2016-11-18 2019-08-16 欧邦特制药公司 用于治疗阿片样物质过量的组合物和方法
AU2018250823A1 (en) 2017-04-10 2019-10-17 Curemark, Llc Compositions for treating addiction
WO2019038687A1 (en) * 2017-08-22 2019-02-28 Euphoria Beer Development Ltd ENRICHED ALCOHOLIC BEVERAGES
MX2020002560A (es) 2017-09-07 2020-07-13 Nls 1 Pharma Ag Tratamiento con mazindol de la dependencia a la heroina y el trastorno de uso de sustancias.
US11160843B2 (en) * 2018-04-30 2021-11-02 Yale University Oxytocin and opioid antagonists for treatment of social dysfunction disorder
AU2019403368A1 (en) * 2018-12-20 2021-07-29 Aegis Therapeutics, Llc Compositions, devices, and methods for the treatment of overdose and reward-based disorders
RU2721606C1 (ru) * 2019-11-08 2020-05-21 Общество с ограниченной ответственностью "Ай Кью Витаминная студия" Фармацевтическая композиция для парентерального капельного введения
US12544385B2 (en) 2020-01-30 2026-02-10 Mohammad JAVED Combination drug therapies for CNS disorders
JP2024521754A (ja) * 2021-05-25 2024-06-04 ザ リージェンツ オブ ザ ユニヴァーシティ オブ コロラド,ア ボディ コーポレイト アルコール使用障害と診断された個体の大量飲酒軽減におけるナルトレキソンのエピジェネティックモデレータの有効性
AU2022323269A1 (en) 2021-08-04 2024-02-29 Indivior Inc. Compositions and methods for the treatment of opioid overdose
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same
AU2023449908A1 (en) * 2023-12-01 2025-06-19 Shenzhen ScienCare Pharmaceutical Co., Ltd. Pharmaceutical composition for preventing relapse into cannabis use and application thereof
WO2025207125A1 (en) * 2024-03-26 2025-10-02 The Regents Of The University Of California Combination pharmacological interventions for obstructive sleep apnea

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5550021A (en) * 1990-02-07 1996-08-27 Board Of Regents, The University Of Texas System Allelic diagnosis of susceptibility to compulsive disorder
EP0714663A3 (en) * 1994-11-28 1997-01-15 Lilly Co Eli Potentiation of drug responses by serotonin 1A receptor antagonists
US20040167164A1 (en) * 1998-05-05 2004-08-26 Jose Pozuelo Compositions and methods for treating particular chemical addictions and mental illnesses
US6287765B1 (en) * 1998-05-20 2001-09-11 Molecular Machines, Inc. Methods for detecting and identifying single molecules
CN100548290C (zh) * 1999-02-24 2009-10-14 辛辛那提大学 氨基磺酸酯衍生物用于治疗冲动控制障碍的用途
WO2002026118A2 (en) * 2000-09-29 2002-04-04 New Health Sciences, Inc. Systems and methods for assessing vascular effects of a treatment
US7122308B2 (en) * 2001-02-16 2006-10-17 Centre For Addiction And Mental Health Detection of antidepressant induced mania
US7033771B2 (en) * 2001-05-08 2006-04-25 Takeda Pharmaceutical Company Limited Use of insulin response modulators in the treatment of diabetes and insulin resistance
RU2004107501A (ru) * 2001-08-14 2005-02-20 Байотай Терапис Корпорейшн (Fi) Способ лечения алкоголизма или злоупотребления алкоголем
WO2003018843A1 (en) * 2001-08-21 2003-03-06 Smithkline Beecham Corporation Gene polymorphisms and response to treatment
US20030114475A1 (en) * 2001-10-31 2003-06-19 Addiction Therapies, Inc. Methods for the treatment of addiction
EP1617832B1 (en) * 2003-04-29 2008-03-12 Orexigen Therapeutics, Inc. Compositions for affecting weight loss
GB0316915D0 (en) * 2003-07-18 2003-08-20 Glaxo Group Ltd Compounds
US7163969B2 (en) * 2003-10-14 2007-01-16 Stockhausen, Inc. Superabsorbent polymer aqueous paste and coating
US20050245461A1 (en) * 2004-03-19 2005-11-03 Elliot Ehrich Methods for treating alcoholism
WO2007039123A2 (en) * 2005-09-22 2007-04-12 Smithkline Beecham Corporation Combination therapy comprising an nk-3 antagonist and an antipsychotic agent
BRPI0616344A2 (pt) * 2005-09-26 2011-06-14 Avigen Inc mÉtodo para o tratamento de dependÊncia quÍmica e comportamental
US20070292880A1 (en) * 2006-05-05 2007-12-20 Robert Philibert Compositions and methods for detecting predisposition to a substance use disorder or to a mental illness or syndrome
US20080004260A1 (en) * 2006-06-29 2008-01-03 Transcept Pharmaceuticals, Inc. Compositions of 5-HT3 antagonists and dopamine D2 antagonists for treatment of dopamine-associated chronic conditions
US7645750B2 (en) * 2006-12-13 2010-01-12 Yung Shin Pharmaceutical Ind. Co., Ltd. Method of treating symptoms of hormonal variations
JP2010513569A (ja) * 2006-12-19 2010-04-30 ユニバーシティ オブ バージニア パテント ファウンデーション アルコール摂取に対するトピラメートおよびオンダンセトロンの併用効果
CA2677205A1 (en) * 2007-01-31 2008-08-07 University Of Virginia Patent Foundation Topiramate plus naltrexone for the treatment of addictive disorders
US20080228700A1 (en) * 2007-03-16 2008-09-18 Expanse Networks, Inc. Attribute Combination Discovery
WO2009026381A2 (en) * 2007-08-21 2009-02-26 University Of Virginia Patent Foundation Method, computer program product and system for individual assessment of alcohol sensitivity
MX2010009509A (es) * 2008-02-28 2010-11-30 Univ Virginia Gen transportador de serotonina y tratamiento de alcoholismo.
WO2009134944A2 (en) * 2008-04-29 2009-11-05 Nodality, Inc. Methods of determining the health status of an individual
EP2425013A1 (en) * 2009-05-01 2012-03-07 University Of Virginia Patent Foundation Serotonin transporter gene and treatment of alcoholism

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2436573C2 (ru) * 2009-07-27 2011-12-20 Учреждение Российской академии медицинских наук Научно-исследовательский институт психического здоровья Сибирского отделения Российской академии медицинских наук (НИИПЗ СО РАМН) Способ реабилитации больных алкоголизмом

Also Published As

Publication number Publication date
JP2010537990A (ja) 2010-12-09
US20110065628A1 (en) 2011-03-17
WO2009029308A1 (en) 2009-03-05

Similar Documents

Publication Publication Date Title
US12221654B2 (en) Serotonin transporter gene and treatment of opioid-related disorders
US20110065628A1 (en) Medication Combinations for the Treatment of Alcoholism and Drug Addiction
US20100076006A1 (en) Topiramate Plus Naltrexone for the Treatment of Addictive Disorders
US20100041689A1 (en) Combined Effects of Topiramate and Ondansetron on Alcohol Consumption
US20090318520A1 (en) Use of isoindoles for the treatment of neurobehavioral disorders
US20120115149A1 (en) Serotonin transporter gene and treatment of alcoholism
CN101663028A (zh) 托吡酯和昂丹司琼对酒精消费的联合效果
HK1151091B (en) Serotonin transporter gene and treatment of alcoholism

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20140521