CA2697043A1 - Procedes et compositions pour le traitement ou la prevention d'une fibrose induite par rayonnement - Google Patents
Procedes et compositions pour le traitement ou la prevention d'une fibrose induite par rayonnement Download PDFInfo
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- CA2697043A1 CA2697043A1 CA2697043A CA2697043A CA2697043A1 CA 2697043 A1 CA2697043 A1 CA 2697043A1 CA 2697043 A CA2697043 A CA 2697043A CA 2697043 A CA2697043 A CA 2697043A CA 2697043 A1 CA2697043 A1 CA 2697043A1
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A—HUMAN NECESSITIES
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- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
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- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95699907P | 2007-08-21 | 2007-08-21 | |
| US60/956,999 | 2007-08-21 | ||
| PCT/US2008/073842 WO2009026428A1 (fr) | 2007-08-21 | 2008-08-21 | Procédés et compositions pour le traitement ou la prévention d'une fibrose induite par rayonnement |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2697043A1 true CA2697043A1 (fr) | 2009-02-26 |
Family
ID=40378641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2697043A Abandoned CA2697043A1 (fr) | 2007-08-21 | 2008-08-21 | Procedes et compositions pour le traitement ou la prevention d'une fibrose induite par rayonnement |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20090069623A1 (fr) |
| EP (1) | EP2192920A4 (fr) |
| CA (1) | CA2697043A1 (fr) |
| WO (1) | WO2009026428A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101762734B1 (ko) | 2008-08-25 | 2017-07-28 | 엑스칼리아드 파마슈티컬즈, 인코포레이티드 | 결합 조직 성장 인자에 대한 안티센스 올리고뉴클레오타이드 및 그의 용도 |
| US8946172B2 (en) * | 2008-08-25 | 2015-02-03 | Excaliard Pharmaceuticals, Inc. | Method for reducing scarring during wound healing using antisense compounds directed to CTGF |
| JP6209309B2 (ja) | 2008-09-22 | 2017-10-04 | アールエックスアイ ファーマシューティカルズ コーポレーション | サイズが減少した自己送達用ＲＮＡｉ化合物 |
| WO2010107952A2 (fr) * | 2009-03-19 | 2010-09-23 | Merck Sharp & Dohme Corp. | Inhibition médiée par arn interférence de l'expression génique de facteur de croissance de tissu conjonctif (ctgf) en utilisant un acide nucléique interférant court (ansi) |
| WO2011056234A1 (fr) * | 2009-11-06 | 2011-05-12 | Fibrogen, Inc. | Traitement de troubles induits par un rayonnement |
| US8600978B2 (en) * | 2009-12-17 | 2013-12-03 | Verizon Patent And Licensing Inc. | Diverse route adjustment tool |
| US9340786B2 (en) | 2010-03-24 | 2016-05-17 | Rxi Pharmaceuticals Corporation | RNA interference in dermal and fibrotic indications |
| EP3578183B1 (fr) | 2010-03-24 | 2021-09-08 | Phio Pharmaceuticals Corp. | Interférence d'arn dans des indications oculaires |
| WO2012061811A2 (fr) | 2010-11-05 | 2012-05-10 | Fibrogen, Inc. | Procédé de traitement de maladies de remodelage des poumons |
| CA2825059A1 (fr) | 2011-02-02 | 2012-08-09 | Excaliard Pharmaceuticals, Inc. | Procede de traitement de cheloides ou de cicatrices hypertrophiees a l'aide de composes antisens ciblant un facteur de croissance de tissu conjonctif (ctgf) |
| WO2013165590A1 (fr) | 2012-05-03 | 2013-11-07 | Fibrogen, Inc. | Méthodes de traitement de la fibrose pulmonaire idiopathique |
| WO2015026494A2 (fr) * | 2013-08-20 | 2015-02-26 | Trustees Of Dartmouth College | Méthodes de traitement de fibrose tissulaire |
| EP3209671B8 (fr) | 2014-10-21 | 2019-07-31 | Council of Scientific and Industrial Research | Esters de phosphonate d'alkylidène en tant qu'inducteurs de p-glycoprotéine |
| CN113747883A (zh) * | 2019-03-29 | 2021-12-03 | 加利福尼亚大学董事会 | 吸入他汀类药物作为支气管扩张剂改善呼吸系统疾病的肺功能 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4490546A (en) * | 1982-03-25 | 1984-12-25 | Merck & Co., Inc. | Process for 4a'(R),5'-dihydromevinolin |
| GB0111077D0 (en) * | 2001-05-04 | 2001-06-27 | Biochemie Gmbh | Organic compounds |
| WO2004024073A2 (fr) * | 2002-09-11 | 2004-03-25 | The Board Of Trustees Of The University Of Arkansas | Utilisation de statines dans la prevention et le traitement de radiolesion et d'autres etats associes a un manque de thrombomoduline endotheliale reduite |
| EP1631279A4 (fr) * | 2003-05-30 | 2007-03-14 | Combinatorx Inc | Therapie combinee pour le traitement des neoplasmes |
| EP1742965B1 (fr) * | 2004-04-28 | 2012-10-24 | Fibrogen, Inc. | Traitements pour le cancer du pancreas |
| TW200716141A (en) * | 2005-05-05 | 2007-05-01 | Combinatorx Inc | Compositions and methods for treatment for neoplasms |
-
2008
- 2008-08-21 US US12/195,845 patent/US20090069623A1/en not_active Abandoned
- 2008-08-21 CA CA2697043A patent/CA2697043A1/fr not_active Abandoned
- 2008-08-21 EP EP08798355A patent/EP2192920A4/fr not_active Withdrawn
- 2008-08-21 WO PCT/US2008/073842 patent/WO2009026428A1/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| US20090069623A1 (en) | 2009-03-12 |
| EP2192920A4 (fr) | 2010-09-01 |
| EP2192920A1 (fr) | 2010-06-09 |
| WO2009026428A1 (fr) | 2009-02-26 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20130821 |