CA2693973A1 - Compositions and methods to detect tmprss2/erg transcript variants in prostate cancer - Google Patents

Compositions and methods to detect tmprss2/erg transcript variants in prostate cancer Download PDF

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Publication number
CA2693973A1
CA2693973A1 CA2693973A CA2693973A CA2693973A1 CA 2693973 A1 CA2693973 A1 CA 2693973A1 CA 2693973 A CA2693973 A CA 2693973A CA 2693973 A CA2693973 A CA 2693973A CA 2693973 A1 CA2693973 A1 CA 2693973A1
Authority
CA
Canada
Prior art keywords
seq
amplification
oligonucleotide
composition
target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2693973A
Other languages
English (en)
French (fr)
Inventor
Paul M. Darby
Siobhan M. Miick
Kumar Kastury
Jo Ann Jackson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gen Probe Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2693973A1 publication Critical patent/CA2693973A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2693973A 2007-07-18 2008-07-17 Compositions and methods to detect tmprss2/erg transcript variants in prostate cancer Abandoned CA2693973A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95039007P 2007-07-18 2007-07-18
US60/950,390 2007-07-18
PCT/US2008/070334 WO2009012387A2 (en) 2007-07-18 2008-07-17 Compositions and methods to detect tmprss2/erg transcript variants in prostate cancer

Publications (1)

Publication Number Publication Date
CA2693973A1 true CA2693973A1 (en) 2009-01-22

Family

ID=40260376

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2693973A Abandoned CA2693973A1 (en) 2007-07-18 2008-07-17 Compositions and methods to detect tmprss2/erg transcript variants in prostate cancer

Country Status (6)

Country Link
US (1) US20100196903A1 (enExample)
EP (1) EP2179049A4 (enExample)
JP (1) JP5622570B2 (enExample)
AU (1) AU2008275978B9 (enExample)
CA (1) CA2693973A1 (enExample)
WO (1) WO2009012387A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11105808B2 (en) 2004-11-12 2021-08-31 Health Discovery Corporation Methods for screening, predicting and monitoring prostate cancer
WO2011037936A2 (en) * 2009-09-24 2011-03-31 Oregon Health & Science University Detection of dna methylation of tal1, erg and/or cd40 to diagnose prostate cancer
EP3448998B1 (en) * 2016-04-27 2020-06-03 Gen-Probe Incorporated Blood cell lysis reagent

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541308A (en) * 1986-11-24 1996-07-30 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
CA2020958C (en) * 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
CA2135073C (en) * 1992-05-06 2002-11-19 Daniel L. Kacian Nucleic acid sequence amplification method, composition and kit
WO2000001850A2 (en) * 1998-07-02 2000-01-13 Gen-Probe Incorporated Molecular torches
US20030073623A1 (en) * 2001-07-30 2003-04-17 Drmanac Radoje T. Novel nucleic acid sequences obtained from various cDNA libraries
CA2931751A1 (en) * 2001-11-02 2003-05-15 Gen-Probe Incorporated Compositions, methods and kits for determining the presence of mycoplasma pneumoniae and/or mycoplasma genitalium in a test sample
JP4457001B2 (ja) * 2002-05-31 2010-04-28 セクレタリー・デパートメント・オブ・アトミック・エナジー ドナー／アクセプター部分が相補鎖上となる標的核酸検出のｍｅｔ／ｆｒｅｔに基づく方法
EP2292801B1 (en) * 2002-06-14 2018-08-08 Gen-Probe Incorporated Compositions and methods for detecting hepatitis b virus
EP2977470B1 (en) * 2002-10-16 2018-01-03 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
AU2005245815B2 (en) * 2004-05-07 2011-06-09 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Methods of diagnosing or treating prostate cancer using the erg gene, alone or in combination with other over or under expressed genes in prostate cancer
US7696337B2 (en) * 2004-08-27 2010-04-13 Gen-Probe Incorporated Composition kits and methods for performing amplification reactions
US7718369B2 (en) * 2005-09-12 2010-05-18 The Regents Of The University Of Michigan Recurrent gene fusions in prostate cancer
US20100087330A1 (en) * 2007-01-26 2010-04-08 Brian Leyland-Jones Breast cancer gene array

Also Published As

Publication number Publication date
JP2010533497A (ja) 2010-10-28
US20100196903A1 (en) 2010-08-05
EP2179049A2 (en) 2010-04-28
WO2009012387A2 (en) 2009-01-22
EP2179049A4 (en) 2011-07-06
WO2009012387A3 (en) 2009-03-26
AU2008275978B9 (en) 2014-11-20
JP5622570B2 (ja) 2014-11-12
AU2008275978B2 (en) 2014-09-11
AU2008275978A1 (en) 2009-01-22

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Legal Events

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EEER Examination request

Effective date: 20130225

FZDE Dead

Effective date: 20160205