CA2693735A1 - Diagnosis and treatment of varicocele and prostate disorders - Google Patents
Diagnosis and treatment of varicocele and prostate disorders Download PDFInfo
- Publication number
- CA2693735A1 CA2693735A1 CA2693735A CA2693735A CA2693735A1 CA 2693735 A1 CA2693735 A1 CA 2693735A1 CA 2693735 A CA2693735 A CA 2693735A CA 2693735 A CA2693735 A CA 2693735A CA 2693735 A1 CA2693735 A1 CA 2693735A1
- Authority
- CA
- Canada
- Prior art keywords
- wire
- catheter
- reflux
- vein
- guide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
- A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1011—Multiple balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
- A61M29/02—Dilators made of swellable material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B18/24—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09175—Guide wires having specific characteristics at the distal tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09175—Guide wires having specific characteristics at the distal tip
- A61M2025/09183—Guide wires having specific characteristics at the distal tip having tools at the distal tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1052—Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1095—Balloon catheters with special features or adapted for special applications with perfusion means for enabling blood circulation while the balloon is in an inflated state or in a deflated state, e.g. permanent by-pass within catheter shaft
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Surgical Instruments (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A method for forestalling or therapy, at least partially, of BPH or prostate cancer comprising identifying a reflux of venous blood to the prostate and impeding the reflux by treating veins effecting or conveying the reflux, and related apparatus and kit.
Claims (60)
1. A method for forestalling or therapy, at least partially, of BPH or prostate cancer comprising:
(a) identifying a reflux of venous blood to the prostate; and (b) impeding the reflux by treating veins causing or conveying the reflux.
(a) identifying a reflux of venous blood to the prostate; and (b) impeding the reflux by treating veins causing or conveying the reflux.
2. A method according to claim 1, wherein causing or conveying comprises having incompetent valves resulting in hydrostatic pressure that prevents upstream venous drainage.
3. A method according to claim 1, wherein treating comprises occlusion one or more veins.
4. A method according to claim 3, wherein occlusion comprises utilizing a sclerosant.
5. A method according to claim 3, wherein occlusion comprises utilizing an element that blocks the vein passage or induces thrombosis.
6. A method according to claim 3, wherein occlusion comprises radiation or thermal or ultrasonic or cryogenic ablation, or a combination thereof.
7. A method according to claim 1, wherein treating comprises a combination of methods.
8. A method according to claim 1, wherein a vein comprises at least one of an internal spermatic vein or a deferential vein or a by-pass vein.
9. A method according to claim 1, wherein the venous blood is rich in testosterone relative to a normal concentration range in the blood circulation.
10. A method for assessing a degree of venous reflux to the prostate comprising:
(a) palpating the prostate for hypertrophy; and (b) inferring a degree of the reflux responsive to the degree of hypertrophy.
(a) palpating the prostate for hypertrophy; and (b) inferring a degree of the reflux responsive to the degree of hypertrophy.
11. A method according to claim 10, wherein the reflux degree is responsive to a unilateral or bilateral reflux or a combination thereof.
12. A method according to claim 10, wherein assessing the degree of the reflux comprises assessing a degree of a malfunction of a spermatic vein valves.
13. A method for assessing a degree of venous reflux to the prostate comprising:
(a) measuring testosterone concentration; and (b) determining a degree of the reflux responsive to the testosterone concentration.
(a) measuring testosterone concentration; and (b) determining a degree of the reflux responsive to the testosterone concentration.
14. A method according to claim 13, wherein the testosterone comprises at least one of free or bound testosterone.
15. A method according to claim 13, wherein assessing the degree of the reflux is responsive to the anatomical location of the measurement.
16. A method according to claim 13, wherein assessing the degree of the reflux comprises assessing a degree of a malfunction of a spermatic vein valves.
17. A method according to claim 13, wherein the measurement comprises a measurement of at least one of a venous blood or arterial blood.
18. A method according to claim 17, wherein the measurement comprises a measurement in a blood vessel at an anatomical location near the prostate before the blood drain to the vena cava.
19. A method for reducing aging symptoms comprising effecting a cause that decreased testosterone supply to the blood stream.
20. A method according to claim 19, wherein effecting comprises impeding a reflux of venous blood.
21. A method according to claim 20, wherein impeding the reflux comprises treating veins effecting or conveying the reflux.
22. A method according to claim 21, wherein treating comprises occlusion.
23. A method according to claim 22, wherein occlusion comprises utilizing at least one of a sclerosant, an element that blocks the vein passage, an element that induces thrombosis, a material that induces thrombosis, ablation or medication.
24. A method according to claim 21, wherein the vein comprises an internal spermatic vein or a deferential vein or a by-pass vein.
25. A method of passing a wire or a catheter through a venous valve, comprising (a) expanding a vein such that a valve orifice is opened; and (b) moving the wire or catheter through the opened orifice.
26. A method according to claim 25, wherein the vein comprises one of an internal spermatic vein, a deferential vein or a by-pass vein in the groin.
27. A method according to claim 25, wherein expanding comprises utilizing an expandable element.
28. A method according to claim 27, wherein the expandable element is contractible.
29. A method according to claim 27, wherein the expandable element comprises a wire mesh.
30. A method according to claim 27, wherein the expandable element comprises an inflatable balloon.
31. A method according to claim 27, wherein the expandable element comprises an elastic element.
32. A guide-wire for passing a catheter through a venous valve comprising:
(a) an expandable element near a distal end of the guide-wire; and (b) an extension at the distal end of the element, forming a flexible tip.
(a) an expandable element near a distal end of the guide-wire; and (b) an extension at the distal end of the element, forming a flexible tip.
33. A guide-wire according to claim 32, wherein the expandable elements is contractible.
34. A guide-wire according to claim 32, wherein the guide-wire comprises a lumen.
35. A guide-wire according to claim 34, wherein a control wire passes through the lumen.
36. A guide-wire according to claim 35, wherein the control wire effects at least one of expanding or contracting the element.
37. A guide-wire according to claim 36, wherein (a) pulling the control wire expands the element; and (b) pushing the control wire retracts the element.
38. A guide-wire according to claim 32, wherein the element comprises a wire mesh.
39. A guide-wire according to claim 32, wherein the element comprises an inflatable balloon.
40. A guide-wire according to claim 32 wherein the element comprises an elastic element.
41. A guide-wire according to claim 32, wherein the element comprises a shape memory material (SMA) expanding or retracting responsive to temperature, or a piezoelectric element expanding or retracting responsive to voltage.
42. A vascular catheter for occluding a region of a blood vessel comprising:
(a) one or more inflatable elements; and (b) one or more perforations along at least part of the catheter for a material application.
(a) one or more inflatable elements; and (b) one or more perforations along at least part of the catheter for a material application.
43. A catheter according to claim 42, wherein the material is a sclerosant injected into the catheter.
44. A catheter according to claim 42, wherein the material is a mechanical element removably attached to the catheter.
45. A catheter according to claim 42, wherein the length of an interval between the inflatable elements is modifiable.
46. A catheter according to claim 42, wherein the material is a glue.
47. A catheter according to claim 42, wherein the catheter applies electric field to induce sclerosis.
48. A catheter according to claim 42, wherein at least some of the perforations are closable.
49. A kit for forestalling or therapy, at least partially, of BPH or prostate cancer, comprising:
(a) a guide-wire for passing a catheter through a venous valve;
(b) a vascular catheter for occluding a region of a blood vessel; and (c) an occlusion material or element.
(a) a guide-wire for passing a catheter through a venous valve;
(b) a vascular catheter for occluding a region of a blood vessel; and (c) an occlusion material or element.
50. A kit according to claim 49, wherein the material comprises at least one of a glue, a sclerosant, or an embolization material.
51. A kit according to claim 49, wherein the element is a coil or an elastic element.
52. A kit according to claim 49, comprising a plurality of the guide-wire or a plurality of the vascular catheters.
53. A kit according to claim 49, wherein the material or elements are sufficient for at least one treatment.
54. A kit according to claim 49, comprising an auxiliary device.
55. A kit according to claim 54, wherein the auxiliary device comprises one of a catheter port, a syringe, or other devices used with the guide-wire or the catheter or the occlusion material or the occlusion element.
56. Use of a sclerosant for the manufacture of medicament for treating BPH or prostate cancer in a subject.
57. A method according to claim 56, wherein said subject age is about 40 or over, 50 or over or 60 or older.
58. A method according to claim 56, wherein said subject was not diagnosed as infertile or not diagnosed for varicocele.
59. Use of a sclerosant for treating prostate hyperplasia or prostate cancer.
60. Use of a vascular cement for treating prostate hyperplasia or prostate cancer.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/826,283 | 2007-07-13 | ||
US11/826,283 US20090018486A1 (en) | 2007-07-13 | 2007-07-13 | Diagnosis and treatment of vericocele and prostate disorders |
US6451108P | 2008-03-10 | 2008-03-10 | |
US61/064,511 | 2008-03-10 | ||
PCT/IL2008/000971 WO2009010962A2 (en) | 2007-07-13 | 2008-07-13 | Diagnosis and treatment of varicocele and prostate disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2693735A1 true CA2693735A1 (en) | 2009-01-22 |
Family
ID=40260179
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2693227A Abandoned CA2693227A1 (en) | 2007-07-13 | 2008-07-13 | Methods and apparatus for treating the prostate |
CA2693225A Abandoned CA2693225A1 (en) | 2007-07-13 | 2008-07-13 | Methods and apparatuses for vascular and prostate treatment |
CA2693735A Abandoned CA2693735A1 (en) | 2007-07-13 | 2008-07-13 | Diagnosis and treatment of varicocele and prostate disorders |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2693227A Abandoned CA2693227A1 (en) | 2007-07-13 | 2008-07-13 | Methods and apparatus for treating the prostate |
CA2693225A Abandoned CA2693225A1 (en) | 2007-07-13 | 2008-07-13 | Methods and apparatuses for vascular and prostate treatment |
Country Status (6)
Country | Link |
---|---|
EP (2) | EP2170180A4 (en) |
JP (1) | JP2010533052A (en) |
CN (1) | CN101801289A (en) |
AU (2) | AU2008277251A1 (en) |
CA (3) | CA2693227A1 (en) |
WO (3) | WO2009010963A2 (en) |
Families Citing this family (22)
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EP2586386B1 (en) * | 2005-01-25 | 2018-10-31 | Covidien LP | Structure for permanent occlusion of a hollow anatomical structure |
EP2566555A1 (en) * | 2010-03-06 | 2013-03-13 | Nfusion Vascular Systems, LLC | Recovery catheter assembly |
US9108029B2 (en) | 2012-05-21 | 2015-08-18 | Nfusion Vascular Systems, Llc | Recovery catheter assembly and method |
EP2858711B1 (en) | 2012-06-06 | 2018-03-07 | Magenta Medical Ltd. | Prosthetic renal valve |
US10583231B2 (en) | 2013-03-13 | 2020-03-10 | Magenta Medical Ltd. | Blood pump |
EP3656293B1 (en) | 2013-03-13 | 2021-08-25 | Magenta Medical Ltd. | Blood pump and blood-impermeable sleeve |
RU2525219C1 (en) * | 2013-04-02 | 2014-08-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Тверская государственная медицинская академия" Министерства здравоохранения Российской Федерации | Method for retrograde sclerotherapy of varicocele in mesenteric-testicular anastomoses |
US9764113B2 (en) | 2013-12-11 | 2017-09-19 | Magenta Medical Ltd | Curved catheter |
CN110013597B (en) * | 2013-12-27 | 2023-02-21 | 睿诺帛医学科技股份有限公司 | Devices and methods for treating acute kidney injury |
RU2572553C1 (en) * | 2014-08-01 | 2016-01-20 | Леонид Зиновьевич Вельшер | Method of treating prostate cancer |
US11291824B2 (en) | 2015-05-18 | 2022-04-05 | Magenta Medical Ltd. | Blood pump |
JP6981967B2 (en) * | 2015-08-31 | 2021-12-17 | ジェンテュイティ・リミテッド・ライアビリティ・カンパニーGentuity, LLC | Imaging system including imaging probe and delivery device |
EP3518825B1 (en) | 2016-09-29 | 2020-05-27 | Magenta Medical Ltd. | Blood vessel tube |
EP3556409B1 (en) | 2016-10-25 | 2022-01-05 | Magenta Medical Ltd. | Ventricular assist device |
CA3039302A1 (en) | 2016-11-23 | 2018-05-31 | Magenta Medical Ltd. | Blood pumps |
US11684242B2 (en) | 2017-11-28 | 2023-06-27 | Gentuity, Llc | Imaging system |
CN115025386A (en) | 2018-01-10 | 2022-09-09 | 马真塔医药有限公司 | Ventricular assist device |
US10905808B2 (en) | 2018-01-10 | 2021-02-02 | Magenta Medical Ltd. | Drive cable for use with a blood pump |
CN108158654B (en) * | 2018-01-12 | 2020-06-12 | 郑州大学第一附属医院 | Portable magnetic induction positioning and guiding device and method thereof |
US10893927B2 (en) | 2018-03-29 | 2021-01-19 | Magenta Medical Ltd. | Inferior vena cava blood-flow implant |
CA3122415A1 (en) | 2019-01-24 | 2020-07-30 | Magenta Medical Ltd | Ventricular assist device |
RU2729431C1 (en) * | 2019-12-27 | 2020-08-06 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Тихоокеанский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Method of laparoscopic treatment of varicocele |
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-
2008
- 2008-07-13 WO PCT/IL2008/000972 patent/WO2009010963A2/en active Application Filing
- 2008-07-13 AU AU2008277251A patent/AU2008277251A1/en not_active Abandoned
- 2008-07-13 JP JP2010516646A patent/JP2010533052A/en active Pending
- 2008-07-13 EP EP08776607A patent/EP2170180A4/en not_active Withdrawn
- 2008-07-13 CN CN200880106666A patent/CN101801289A/en active Pending
- 2008-07-13 AU AU2008277252A patent/AU2008277252A1/en not_active Abandoned
- 2008-07-13 WO PCT/IL2008/000973 patent/WO2009010964A2/en active Application Filing
- 2008-07-13 CA CA2693227A patent/CA2693227A1/en not_active Abandoned
- 2008-07-13 WO PCT/IL2008/000971 patent/WO2009010962A2/en active Application Filing
- 2008-07-13 CA CA2693225A patent/CA2693225A1/en not_active Abandoned
- 2008-07-13 EP EP08776606A patent/EP2178594A4/en not_active Withdrawn
- 2008-07-13 CA CA2693735A patent/CA2693735A1/en not_active Abandoned
Also Published As
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EP2170180A2 (en) | 2010-04-07 |
AU2008277251A1 (en) | 2009-01-22 |
WO2009010962A2 (en) | 2009-01-22 |
EP2178594A4 (en) | 2011-02-23 |
JP2010533052A (en) | 2010-10-21 |
CA2693227A1 (en) | 2009-01-22 |
WO2009010964A3 (en) | 2010-02-25 |
WO2009010962A3 (en) | 2010-09-16 |
CN101801289A (en) | 2010-08-11 |
EP2178594A2 (en) | 2010-04-28 |
EP2170180A4 (en) | 2011-02-23 |
WO2009010963A3 (en) | 2010-01-14 |
WO2009010963A2 (en) | 2009-01-22 |
WO2009010964A2 (en) | 2009-01-22 |
CA2693225A1 (en) | 2009-01-22 |
AU2008277252A1 (en) | 2009-01-22 |
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