CA2685213C - Engineered rabbit antibody variable domains and uses thereof - Google Patents

Engineered rabbit antibody variable domains and uses thereof Download PDF

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Publication number
CA2685213C
CA2685213C CA2685213A CA2685213A CA2685213C CA 2685213 C CA2685213 C CA 2685213C CA 2685213 A CA2685213 A CA 2685213A CA 2685213 A CA2685213 A CA 2685213A CA 2685213 C CA2685213 C CA 2685213C
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domain
polypeptide
amino acid
rabbit
antigen
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CA2685213A
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English (en)
French (fr)
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CA2685213A1 (en
Inventor
Joao Manuel Braz Goncalves
Frederico Nuno Castanheira Aires Da Silva
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technophage Investigacao e Desenvolvimento em Biotecnologia SA
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Technophage Investigacao e Desenvolvimento em Biotecnologia SA
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Publication of CA2685213A1 publication Critical patent/CA2685213A1/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CA2685213A 2007-05-04 2008-04-30 Engineered rabbit antibody variable domains and uses thereof Active CA2685213C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91622607P 2007-05-04 2007-05-04
US60/916,226 2007-05-04
PCT/PT2008/000018 WO2008136694A1 (en) 2007-05-04 2008-04-30 Engineered rabbit antibody variable domains and uses thereof

Publications (2)

Publication Number Publication Date
CA2685213A1 CA2685213A1 (en) 2008-11-13
CA2685213C true CA2685213C (en) 2017-02-21

Family

ID=39735911

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2685213A Active CA2685213C (en) 2007-05-04 2008-04-30 Engineered rabbit antibody variable domains and uses thereof

Country Status (9)

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US (2) US10280211B2 (OSRAM)
EP (1) EP2164868B1 (OSRAM)
JP (3) JP5791895B2 (OSRAM)
AU (1) AU2008246442B2 (OSRAM)
CA (1) CA2685213C (OSRAM)
ES (1) ES2540807T3 (OSRAM)
PT (1) PT2164868E (OSRAM)
SG (1) SG194368A1 (OSRAM)
WO (1) WO2008136694A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104144944B (zh) * 2012-02-29 2016-06-29 大塚制药株式会社 抗-脂阿拉伯甘露聚糖抗体和使用该抗体对抗酸杆菌感染的免疫测定
CN107531781B (zh) * 2015-01-29 2021-12-07 抗菌技术,生物技术研究与发展股份有限公司 用于阿尔茨海默病和相关紊乱的抗体分子和肽递送系统
US11685773B2 (en) 2015-04-30 2023-06-27 Abcheck S.R.O. Method for mass humanization of rabbit antibodies
DK3795591T5 (da) 2015-06-19 2024-08-19 Eisai R&D Man Co Ltd Cys80-konjugerede immunoglobuliner
EP4401835A4 (en) * 2021-09-13 2025-07-30 Univ Texas TREM2 ANTIGEN-BINDING PROTEINS AND THEIR USES

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Also Published As

Publication number Publication date
JP2015012869A (ja) 2015-01-22
US10280211B2 (en) 2019-05-07
AU2008246442A1 (en) 2008-11-13
JP2010525808A (ja) 2010-07-29
ES2540807T3 (es) 2015-07-13
SG194368A1 (en) 2013-11-29
US20190256578A1 (en) 2019-08-22
EP2164868A1 (en) 2010-03-24
WO2008136694A9 (en) 2010-09-02
EP2164868B1 (en) 2015-03-25
JP2015164940A (ja) 2015-09-17
JP5791895B2 (ja) 2015-10-07
WO2008136694A1 (en) 2008-11-13
AU2008246442B2 (en) 2014-07-03
CA2685213A1 (en) 2008-11-13
US20100136627A1 (en) 2010-06-03
PT2164868E (pt) 2015-08-04

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