CA2681522A1 - Cyclic receptor-associated protein (rap) peptides - Google Patents
Cyclic receptor-associated protein (rap) peptides Download PDFInfo
- Publication number
- CA2681522A1 CA2681522A1 CA002681522A CA2681522A CA2681522A1 CA 2681522 A1 CA2681522 A1 CA 2681522A1 CA 002681522 A CA002681522 A CA 002681522A CA 2681522 A CA2681522 A CA 2681522A CA 2681522 A1 CA2681522 A1 CA 2681522A1
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- CA
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- Prior art keywords
- rap
- peptide
- cyclic
- mutation
- cyclic rap
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91923807P | 2007-03-21 | 2007-03-21 | |
| US60/919,238 | 2007-03-21 | ||
| PCT/US2008/057863 WO2008116171A1 (en) | 2007-03-21 | 2008-03-21 | Cyclic receptor-associated protein (rap) peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2681522A1 true CA2681522A1 (en) | 2008-09-25 |
Family
ID=39591450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002681522A Abandoned CA2681522A1 (en) | 2007-03-21 | 2008-03-21 | Cyclic receptor-associated protein (rap) peptides |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8440629B2 (enExample) |
| EP (1) | EP2132224B1 (enExample) |
| JP (1) | JP2010524849A (enExample) |
| KR (2) | KR101801454B1 (enExample) |
| CN (1) | CN101861334A (enExample) |
| AT (1) | ATE539089T1 (enExample) |
| BR (1) | BRPI0809234A2 (enExample) |
| CA (1) | CA2681522A1 (enExample) |
| MX (1) | MX2009010148A (enExample) |
| WO (1) | WO2008116171A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE512674T1 (de) | 2003-01-06 | 2011-07-15 | Angiochem Inc | Angiopep-1, verwandte verbindungen, und deren verwnedungen |
| US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| CN102026667B (zh) | 2008-04-18 | 2014-06-25 | 安吉奥开米公司 | 紫杉醇、紫杉醇类似物或紫杉醇结合物的药物组合物及相关制备方法和用途 |
| US8129341B2 (en) * | 2008-08-25 | 2012-03-06 | New York University | Methods for treating diabetic wounds |
| WO2010043047A1 (en) | 2008-10-15 | 2010-04-22 | Angiochem Inc. | Conjugates of glp-1 agonists and uses thereof |
| US8828925B2 (en) | 2008-10-15 | 2014-09-09 | Angiochem Inc. | Etoposide and doxorubicin conjugates for drug delivery |
| WO2010063122A1 (en) | 2008-12-05 | 2010-06-10 | Angiochem Inc. | Conjugates of neurotensin or neurotensin analogs and uses thereof |
| EP2373789A4 (en) | 2008-12-17 | 2012-08-29 | Angiochem Inc | MEMBRANTYP-1 MATRIX METALLOPROTEINASE INHIBITORS AND THEIR USE |
| CA2757645C (en) * | 2009-04-06 | 2018-05-15 | Mayo Foundation For Medical Education And Research | Methods and materials for delivering molecules |
| RU2011146654A (ru) | 2009-04-20 | 2013-05-27 | Ангиокем Инк. | Способы лечения рака яичников с применением конъюгированного средства |
| WO2011000095A1 (en) | 2009-07-02 | 2011-01-06 | Angiochem Inc. | Multimeric peptide conjugates and uses thereof |
| JP6170675B2 (ja) * | 2010-01-28 | 2017-07-26 | ラプトール ファーマシューティカルズ インコーポレイテッド | 受容体関連タンパク質（ｒａｐ）ペプチド−フコシダーゼ阻害薬複合体による肝障害処置のための方法 |
| WO2011160082A2 (en) | 2010-06-17 | 2011-12-22 | New York University | Therapeutic and cosmetic uses and applications of calreticulin |
| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| GB201220474D0 (en) * | 2012-11-14 | 2012-12-26 | Sagetis Biotech Sl | Polypeptides |
| US20150093399A1 (en) | 2013-08-28 | 2015-04-02 | Bioasis Technologies, Inc. | Cns-targeted conjugates having modified fc regions and methods of use thereof |
| US20180021404A1 (en) * | 2015-02-20 | 2018-01-25 | The Regents Of The University Of California | Methods and compositions for treating glaucoma |
| EP3307326B9 (en) | 2015-06-15 | 2021-02-24 | Angiochem Inc. | Methods for the treatment of leptomeningeal carcinomatosis |
| CN109422801B (zh) * | 2017-08-31 | 2022-07-08 | 复旦大学 | 多功能靶向多肽rap及其在制备肿瘤靶向递送系统中的用途 |
| WO2019108806A1 (en) * | 2017-11-29 | 2019-06-06 | Board Of Regents Of The University Of Texas System | Compositions and methods for cancer therapy |
| US12305171B2 (en) | 2018-12-27 | 2025-05-20 | Bioaffinity Technologies, Inc. | Compositions and methods for treating cancer |
| CA3163139A1 (en) * | 2018-12-27 | 2020-07-02 | Vivienne I. Rebel | Compositions and methods for treating cancer |
| US11572394B2 (en) * | 2020-02-16 | 2023-02-07 | Pasteur Institute Of Iran | Peptides for targeting LRP6-overexpressed cells |
| CA3128035A1 (en) | 2020-08-13 | 2022-02-13 | Bioasis Technologies, Inc. | Combination therapies for delivery across the blood brain barrier |
| CN116286380B (zh) * | 2021-12-21 | 2026-01-09 | 暨南大学 | 环五肽类化合物及其在α-糖苷酶抑制剂类降糖药物或预防保健品中的应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4394448A (en) * | 1978-02-24 | 1983-07-19 | Szoka Jr Francis C | Method of inserting DNA into living cells |
| IT1122765B (it) * | 1978-11-06 | 1986-04-23 | Srm Hydromekanik Ab | Frizione a dischi multipli |
| US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
| US5186941A (en) * | 1983-05-06 | 1993-02-16 | Vestar, Inc. | Vesicle formulation for the controlled release of therapeutic agents |
| US6048729A (en) * | 1987-05-01 | 2000-04-11 | Transkaryotic Therapies, Inc. | In vivo protein production and delivery system for gene therapy |
| US6063630A (en) * | 1991-11-05 | 2000-05-16 | Transkaryotic Therapies, Inc. | Targeted introduction of DNA into primary or secondary cells and their use for gene therapy |
| US6238908B1 (en) * | 1995-06-07 | 2001-05-29 | Aastrom Biosciences, Inc. | Apparatus and method for maintaining and growth biological cells |
| EP0893949B1 (en) * | 1996-01-16 | 2005-04-27 | Ronald J. Sokol | Use of antioxidant agents to treat cholestatic liver disease |
| TW492882B (en) * | 1997-11-28 | 2002-07-01 | Caleb Pharmaceuticals Inc | Cholinergic antagonist plaster composition |
| US6585971B1 (en) * | 1999-11-12 | 2003-07-01 | Harbor-Ucla Research And Education Institute | Recombinant α-L-iduronidase, methods for producing and purifying the same and methods for treating disease caused by deficiencies thereof |
| US6569661B1 (en) * | 1999-11-12 | 2003-05-27 | Biomarin Pharmaceutical Inc. | Recombinant α-L-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof |
| US6426208B1 (en) * | 1999-11-12 | 2002-07-30 | Harbor-Ucla Research And Education Institute | Recombinant α-L-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof |
| US6261595B1 (en) * | 2000-02-29 | 2001-07-17 | Zars, Inc. | Transdermal drug patch with attached pocket for controlled heating device |
| US6596762B2 (en) * | 2001-05-17 | 2003-07-22 | The Regents Of The University Of Colorado | Antioxidant compositions and use for treatment of hepatic steatosis and steatohepatitis |
| US7485314B2 (en) * | 2002-05-06 | 2009-02-03 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Induction of antigen specific immunologic tolerance |
| WO2005002515A2 (en) * | 2003-06-20 | 2005-01-13 | Biomarin Pharmaceutical Inc. | Delivery of therapeutic compounds to the brain and other tissues |
| US8877714B2 (en) * | 2005-06-14 | 2014-11-04 | Raptor Pharmaceutical Inc. | Compositions comprising receptor-associated protein (RAP) variants specific for LRP2 and uses thereof |
| JP2010503710A (ja) * | 2006-09-18 | 2010-02-04 | ラプトール ファーマシューティカル インコーポレイテッド | 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置 |
-
2008
- 2008-03-21 AT AT08732675T patent/ATE539089T1/de active
- 2008-03-21 CN CN200880016942A patent/CN101861334A/zh active Pending
- 2008-03-21 US US12/600,786 patent/US8440629B2/en not_active Expired - Fee Related
- 2008-03-21 MX MX2009010148A patent/MX2009010148A/es active IP Right Grant
- 2008-03-21 KR KR1020157020697A patent/KR101801454B1/ko not_active Expired - Fee Related
- 2008-03-21 JP JP2010501126A patent/JP2010524849A/ja active Pending
- 2008-03-21 BR BRPI0809234-6A patent/BRPI0809234A2/pt not_active Application Discontinuation
- 2008-03-21 KR KR1020097022037A patent/KR20100015786A/ko not_active Ceased
- 2008-03-21 WO PCT/US2008/057863 patent/WO2008116171A1/en not_active Ceased
- 2008-03-21 EP EP08732675A patent/EP2132224B1/en not_active Not-in-force
- 2008-03-21 CA CA002681522A patent/CA2681522A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008116171A1 (en) | 2008-09-25 |
| EP2132224B1 (en) | 2011-12-28 |
| HK1139162A1 (en) | 2010-09-10 |
| MX2009010148A (es) | 2009-12-01 |
| US20100210517A1 (en) | 2010-08-19 |
| CN101861334A (zh) | 2010-10-13 |
| JP2010524849A (ja) | 2010-07-22 |
| US8440629B2 (en) | 2013-05-14 |
| KR101801454B1 (ko) | 2017-11-24 |
| BRPI0809234A2 (pt) | 2014-09-02 |
| EP2132224A1 (en) | 2009-12-16 |
| ATE539089T1 (de) | 2012-01-15 |
| KR20150104584A (ko) | 2015-09-15 |
| KR20100015786A (ko) | 2010-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20130311 |
|
| FZDE | Discontinued |
Effective date: 20190828 |