CA2680661C - Mutant reoviruses and methods of making and using - Google Patents
Mutant reoviruses and methods of making and using Download PDFInfo
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- CA2680661C CA2680661C CA2680661A CA2680661A CA2680661C CA 2680661 C CA2680661 C CA 2680661C CA 2680661 A CA2680661 A CA 2680661A CA 2680661 A CA2680661 A CA 2680661A CA 2680661 C CA2680661 C CA 2680661C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
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- C12N2720/12022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
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- Immunology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Oncology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93925507P | 2007-05-21 | 2007-05-21 | |
| US60/939,255 | 2007-05-21 | ||
| PCT/CA2008/000964 WO2008141448A1 (en) | 2007-05-21 | 2008-05-21 | Mutant reoviruses and methods of making and using |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2680661A1 CA2680661A1 (en) | 2008-11-27 |
| CA2680661C true CA2680661C (en) | 2018-05-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2680661A Active CA2680661C (en) | 2007-05-21 | 2008-05-21 | Mutant reoviruses and methods of making and using |
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| Country | Link |
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| US (1) | US20080292594A1 (OSRAM) |
| EP (1) | EP2150613B1 (OSRAM) |
| JP (1) | JP2010527593A (OSRAM) |
| CN (2) | CN104195115A (OSRAM) |
| AR (1) | AR066649A1 (OSRAM) |
| AU (1) | AU2008253505B2 (OSRAM) |
| CA (1) | CA2680661C (OSRAM) |
| DK (1) | DK2150613T3 (OSRAM) |
| ES (1) | ES2611455T3 (OSRAM) |
| IL (1) | IL200690A (OSRAM) |
| MX (1) | MX2009012420A (OSRAM) |
| TW (1) | TW200909581A (OSRAM) |
| WO (1) | WO2008141448A1 (OSRAM) |
| ZA (1) | ZA200907017B (OSRAM) |
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| GB0720624D0 (en) * | 2007-10-20 | 2007-11-28 | Academisch Ziekenhuis Leiden | Viral Modification |
| MX2010003556A (es) * | 2007-10-22 | 2010-04-21 | Oncolytics Biotech Inc | Regimen de tratamiento para trastornos proliferantes. |
| WO2009143610A1 (en) * | 2008-05-27 | 2009-12-03 | Oncolytics Biotech Inc. | Modulating interstitial pressure and oncolytic viral delivery and distribution |
| JP2011520994A (ja) * | 2008-05-27 | 2011-07-21 | オンコリティクス バイオテク，インコーポレーテッド | 腫瘍崩解性レオウイルス療法中の炎症性サイトカイン産生の排除 |
| EP2646052B1 (en) | 2010-12-02 | 2017-03-29 | Oncolytics Biotech Inc. | Lyophilized viral formulations |
| CN103347535B (zh) | 2010-12-02 | 2015-11-25 | 昂科利蒂克斯生物科技公司 | 液体病毒制剂 |
| ES2796950T3 (es) | 2013-11-15 | 2020-11-30 | Oncolytics Biotech Inc | Virus oncolíticos y regímenes reforzados para tratamiento de cáncer |
| WO2017141942A1 (ja) | 2016-02-16 | 2017-08-24 | 国立大学法人大阪大学 | 線維化を治療するための医薬組成物 |
| KR20210098202A (ko) * | 2020-01-31 | 2021-08-10 | 바이로큐어 주식회사 | 레오바이러스를 유효성분으로 포함하는 대장염의 예방 또는 치료용 조성물 |
| KR20220090467A (ko) * | 2020-12-22 | 2022-06-29 | 바이로큐어 주식회사 | 신규한 변형 레오바이러스 및 이의 용도 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4554101A (en) * | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US5023252A (en) * | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
| US6565831B1 (en) * | 1999-02-24 | 2003-05-20 | Oncolytics Biotech Inc. | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders |
| US6136307A (en) * | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
| PT1098961E (pt) * | 1998-06-12 | 2008-04-23 | Mount Sinai School Of Med Of T | Vírus atenuados produzidos por engenharia genética indutores de interferão |
| TWI289158B (en) * | 2000-08-10 | 2007-11-01 | Oncolytics Biotech Inc | Method of producing infectious reovirus |
| ES2347523T3 (es) * | 2000-11-09 | 2010-11-02 | Oncolytics Biotech, Inc. | Metodos para el tratamiento de trastornos proliferativos celulares. |
| CA2437962C (en) * | 2001-03-16 | 2005-11-15 | Oncolytics Biotech Inc. | Method of extracting virus from cell culture |
| US7163678B2 (en) * | 2002-11-07 | 2007-01-16 | Oncolytics Biotech Inc. | Reovirus for the treatment of ral-mediated cellular proliferative disorders |
| WO2005111200A1 (en) * | 2004-05-17 | 2005-11-24 | Universite De Montreal | Novel strains of reoviruses and methods of uses thereof |
| EP1917351A4 (en) * | 2005-08-01 | 2009-12-16 | Univ Technologies Int | ATTENUATED REOVIRUS |
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2008
- 2008-05-20 AR ARP080102139A patent/AR066649A1/es unknown
- 2008-05-20 TW TW097118468A patent/TW200909581A/zh unknown
- 2008-05-21 ES ES08748334.3T patent/ES2611455T3/es active Active
- 2008-05-21 WO PCT/CA2008/000964 patent/WO2008141448A1/en not_active Ceased
- 2008-05-21 DK DK08748334.3T patent/DK2150613T3/en active
- 2008-05-21 CN CN201410339446.7A patent/CN104195115A/zh active Pending
- 2008-05-21 AU AU2008253505A patent/AU2008253505B2/en active Active
- 2008-05-21 CA CA2680661A patent/CA2680661C/en active Active
- 2008-05-21 US US12/124,522 patent/US20080292594A1/en not_active Abandoned
- 2008-05-21 MX MX2009012420A patent/MX2009012420A/es active IP Right Grant
- 2008-05-21 CN CN200880016669A patent/CN101679953A/zh active Pending
- 2008-05-21 JP JP2010508676A patent/JP2010527593A/ja active Pending
- 2008-05-21 EP EP08748334.3A patent/EP2150613B1/en active Active
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2009
- 2009-09-02 IL IL200690A patent/IL200690A/en active IP Right Grant
- 2009-10-08 ZA ZA2009/07017A patent/ZA200907017B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR066649A1 (es) | 2009-09-02 |
| ES2611455T3 (es) | 2017-05-09 |
| ZA200907017B (en) | 2010-12-29 |
| AU2008253505A1 (en) | 2008-11-27 |
| EP2150613B1 (en) | 2016-10-19 |
| EP2150613A1 (en) | 2010-02-10 |
| CA2680661A1 (en) | 2008-11-27 |
| EP2150613A4 (en) | 2011-01-19 |
| US20080292594A1 (en) | 2008-11-27 |
| CN104195115A (zh) | 2014-12-10 |
| MX2009012420A (es) | 2009-12-09 |
| IL200690A (en) | 2014-02-27 |
| IL200690A0 (en) | 2011-08-01 |
| CN101679953A (zh) | 2010-03-24 |
| JP2010527593A (ja) | 2010-08-19 |
| AU2008253505B2 (en) | 2014-09-04 |
| WO2008141448A1 (en) | 2008-11-27 |
| DK2150613T3 (en) | 2017-01-30 |
| TW200909581A (en) | 2009-03-01 |
| HK1136006A1 (en) | 2010-06-18 |
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