CA2676907C - Tricyclic compounds and their use as glucocorticoid receptor modulators - Google Patents
Tricyclic compounds and their use as glucocorticoid receptor modulators Download PDFInfo
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Classifications
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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Landscapes
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- Epidemiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88798107P | 2007-02-02 | 2007-02-02 | |
| US60/887,981 | 2007-02-02 | ||
| PCT/IB2008/000249 WO2008093236A1 (en) | 2007-02-02 | 2008-01-28 | Tricyclic compounds and their use as glucocorticoid receptor modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2676907A1 CA2676907A1 (en) | 2008-08-07 |
| CA2676907C true CA2676907C (en) | 2012-03-20 |
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|---|---|---|---|
| CA2676907A Expired - Fee Related CA2676907C (en) | 2007-02-02 | 2008-01-28 | Tricyclic compounds and their use as glucocorticoid receptor modulators |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP2114888B1 (OSRAM) |
| JP (1) | JP4579333B2 (OSRAM) |
| AP (1) | AP2411A (OSRAM) |
| AT (1) | ATE487700T1 (OSRAM) |
| AU (1) | AU2008211622B2 (OSRAM) |
| BR (1) | BRPI0807121A2 (OSRAM) |
| CA (1) | CA2676907C (OSRAM) |
| DE (1) | DE602008003405D1 (OSRAM) |
| DK (1) | DK2114888T3 (OSRAM) |
| EA (1) | EA016001B1 (OSRAM) |
| HR (1) | HRP20100726T1 (OSRAM) |
| IL (1) | IL200044A (OSRAM) |
| MX (1) | MX2009008286A (OSRAM) |
| NZ (1) | NZ578661A (OSRAM) |
| PL (1) | PL2114888T3 (OSRAM) |
| SI (1) | SI2114888T1 (OSRAM) |
| UZ (1) | UZ4378C (OSRAM) |
| WO (1) | WO2008093236A1 (OSRAM) |
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| WO2008093227A1 (en) * | 2007-02-02 | 2008-08-07 | Pfizer Products Inc. | Tricyclic compounds and their use as glucocorticoid receptor modulators |
| ES2527137T3 (es) * | 2008-07-28 | 2015-01-21 | Pfizer Inc. | Compuestos de fenantrenona, composiciones y procedimientos |
| WO2012125797A1 (en) * | 2011-03-15 | 2012-09-20 | Abbott Laboratories | Nuclear hormone receptor modulators |
| US20140350078A1 (en) * | 2011-09-13 | 2014-11-27 | New York University | Controlling regulatory t cell function |
| TW201422590A (zh) | 2012-09-07 | 2014-06-16 | Abbvie Inc | 雜環核激素受體調節劑 |
| EP2935284A4 (en) | 2012-12-21 | 2016-04-27 | Abbvie Inc | HETEROCYCLIC MODULATORS OF HORMONE NUCLEAR RECEPTORS |
| KR20180050408A (ko) * | 2015-09-15 | 2018-05-14 | 레오 파마 에이/에스 | 국부 약물 전달용의 비스테로이드성 글루코코르티코이드 수용체 조절제 |
| CN113164448A (zh) | 2018-12-19 | 2021-07-23 | 利奥制药有限公司 | 作为il-17的小分子调节剂的氨基酸苯胺类化合物 |
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| HK1042889B (zh) * | 1999-04-30 | 2006-12-29 | 辉瑞产品公司 | 糖皮质激素受体调制剂 |
| JP4738603B2 (ja) * | 2000-11-06 | 2011-08-03 | ライオン株式会社 | 歯ブラシ |
| IL180679A0 (en) * | 2000-10-27 | 2009-02-11 | Pfizer Prod Inc | Process for the preparation of non-steroidal glucocorticoid receptor modulators |
| JP2002193911A (ja) * | 2000-10-28 | 2002-07-10 | Pfizer Prod Inc | グルココルチコイドレセプターモジュレーター |
| AU2004289532A1 (en) * | 2003-11-13 | 2005-05-26 | Pfizer Products Inc. | Octahydrophenanthrene hydrazinde derivatives useful as glucocorticoid receptor modulators |
| AU2007248059A1 (en) * | 2006-05-02 | 2007-11-15 | Corcept Therapeutics, Inc. | The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2 |
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- 2008-01-28 AT AT08702358T patent/ATE487700T1/de active
- 2008-01-28 AP AP2009004941A patent/AP2411A/xx active
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- 2008-01-28 CA CA2676907A patent/CA2676907C/en not_active Expired - Fee Related
- 2008-01-28 MX MX2009008286A patent/MX2009008286A/es active IP Right Grant
- 2008-01-28 WO PCT/IB2008/000249 patent/WO2008093236A1/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2010517991A (ja) | 2010-05-27 |
| UZ4378C (en) | 2011-07-29 |
| DK2114888T3 (da) | 2011-01-24 |
| ATE487700T1 (de) | 2010-11-15 |
| CA2676907A1 (en) | 2008-08-07 |
| IL200044A (en) | 2015-06-30 |
| IL200044A0 (en) | 2010-04-15 |
| WO2008093236A1 (en) | 2008-08-07 |
| JP4579333B2 (ja) | 2010-11-10 |
| AU2008211622B2 (en) | 2012-04-19 |
| SI2114888T1 (sl) | 2011-02-28 |
| HRP20100726T1 (hr) | 2011-04-30 |
| EP2114888B1 (en) | 2010-11-10 |
| BRPI0807121A2 (pt) | 2014-04-08 |
| HK1135094A1 (en) | 2010-05-28 |
| AP2411A (en) | 2012-05-30 |
| NZ578661A (en) | 2010-12-24 |
| DE602008003405D1 (de) | 2010-12-23 |
| EA016001B1 (ru) | 2012-01-30 |
| EP2114888A1 (en) | 2009-11-11 |
| PL2114888T3 (pl) | 2011-04-29 |
| AP2009004941A0 (en) | 2009-08-31 |
| MX2009008286A (es) | 2009-08-12 |
| AU2008211622A1 (en) | 2008-08-07 |
| EA200970662A1 (ru) | 2010-02-26 |
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