CA2672606A1 - Compositions and methods to treat muscular & cardiovascular disorders - Google Patents
Compositions and methods to treat muscular & cardiovascular disorders Download PDFInfo
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- CA2672606A1 CA2672606A1 CA002672606A CA2672606A CA2672606A1 CA 2672606 A1 CA2672606 A1 CA 2672606A1 CA 002672606 A CA002672606 A CA 002672606A CA 2672606 A CA2672606 A CA 2672606A CA 2672606 A1 CA2672606 A1 CA 2672606A1
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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| US60/869,937 | 2006-12-14 | ||
| PCT/US2007/025535 WO2008076324A2 (en) | 2006-12-14 | 2007-12-13 | Compositions and methods to treat muscular & cardiovascular disorders |
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| JP (3) | JP2010512747A (enExample) |
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| WO (1) | WO2008076324A2 (enExample) |
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| ES2397439T3 (es) | 2006-08-01 | 2013-03-07 | Board Of Regents Of The University Of Texas System | Identificación de un microARN que activa la expresión de la cadena pesada beta de la miosina |
| US8481507B2 (en) * | 2007-07-31 | 2013-07-09 | The Board Of Regents, The University Of Texas System | Micro-RNAs that control myosin expression and myofiber identity |
| MX2011008190A (es) * | 2009-02-04 | 2011-10-06 | Univ Texas | Direccionamiento dual de mir-208 y mir-499 en el tratamiento de trastornos cardiacos. |
| IE20090047A1 (en) * | 2009-02-26 | 2010-09-29 | Nat Univ Ireland | Protein targets in disease |
| EP2703501A1 (en) * | 2009-03-12 | 2014-03-05 | Brandeis University | Reagents and Methods for PCR |
| CN103380215A (zh) | 2010-12-15 | 2013-10-30 | 米拉根医疗公司 | 包含锁定核苷酸的微rna抑制剂 |
| JP6177243B2 (ja) | 2011-10-06 | 2017-08-09 | ミラゲン セラピューティクス， インコーポレイテッド | マイクロｒｎａの調節による全身エネルギーホメオスタシスの制御 |
| DK3354734T3 (da) | 2012-06-21 | 2020-06-29 | Miragen Therapeutics Inc | Oligonukleotid-baserede hæmmere omfattende låst nukleinsyremønster |
| US10443052B2 (en) * | 2012-10-15 | 2019-10-15 | Ionis Pharmaceuticals, Inc. | Compositions for modulating C9ORF72 expression |
| WO2014062736A1 (en) | 2012-10-15 | 2014-04-24 | Isis Pharmaceuticals, Inc. | Methods for monitoring c9orf72 expression |
| US9637738B2 (en) * | 2013-04-10 | 2017-05-02 | Reveragen Biopharma, Inc. | Methods and agents to increase therapeutic dystrophin expression in muscle |
| MX2016004651A (es) | 2013-10-11 | 2016-08-05 | Ionis Pharmaceuticals Inc | Composiciones para modular la expresion de c9orf72. |
| WO2016022536A2 (en) * | 2014-08-04 | 2016-02-11 | MiRagen Therapeutics, Inc. | Inhibitors of myh7b and uses thereof |
| US9885042B2 (en) | 2015-01-20 | 2018-02-06 | MiRagen Therapeutics, Inc. | miR-92 inhibitors and uses thereof |
| EP3722424A1 (en) | 2015-04-16 | 2020-10-14 | Ionis Pharmaceuticals, Inc. | Compositions for modulating c9orf72 expression |
| WO2017079291A1 (en) | 2015-11-02 | 2017-05-11 | Ionis Pharmaceuticals, Inc. | Compounds and methods for modulating c90rf72 |
| CN106148519A (zh) * | 2016-07-05 | 2016-11-23 | 无锡市第二人民医院 | 一种microRNA‑499的快速检测方法 |
| WO2019014656A1 (en) | 2017-07-14 | 2019-01-17 | Han Si Ping | METALLIC OLIGONUCLEOTIDE JONCTIONS FOR THE ADMINISTRATION OF THERAPEUTIC AGENTS |
| CN111630166B (zh) * | 2017-08-10 | 2024-04-19 | 希望之城 | 条件性-siRNA及其在治疗心肌肥大中的用途 |
| KR102281710B1 (ko) | 2021-02-19 | 2021-07-28 | 조기정 | 에어튜브를 이용한 선박 안전장치 |
| CN119246849B (zh) * | 2024-12-09 | 2025-03-14 | 上海基灵生物科技有限公司 | 一种检测犬心脏损伤的试剂盒及应用 |
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| US5602240A (en) * | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| US5489677A (en) * | 1990-07-27 | 1996-02-06 | Isis Pharmaceuticals, Inc. | Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms |
| ES2083593T3 (es) * | 1990-08-03 | 1996-04-16 | Sterling Winthrop Inc | Compuestos y metodos para inhibir la expresion de genes. |
| US5719262A (en) * | 1993-11-22 | 1998-02-17 | Buchardt, Deceased; Ole | Peptide nucleic acids having amino acid side chains |
| US5700922A (en) * | 1991-12-24 | 1997-12-23 | Isis Pharmaceuticals, Inc. | PNA-DNA-PNA chimeric macromolecules |
| JP3516167B2 (ja) * | 1992-12-08 | 2004-04-05 | ローム株式会社 | タンタルコンデンサチップの製造方法 |
| US6271359B1 (en) * | 1999-04-14 | 2001-08-07 | Musc Foundation For Research Development | Tissue-specific and pathogen-specific toxic agents and ribozymes |
| KR100909681B1 (ko) * | 2000-12-01 | 2009-07-29 | 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. | Ｒｎａ 간섭을 매개하는 작은 ｒｎａ 분자 |
| CN101291653B (zh) * | 2003-07-16 | 2012-06-27 | 普洛体维生物治疗公司 | 脂质包封的干扰rna |
| WO2005021800A2 (en) * | 2003-08-22 | 2005-03-10 | Sirna Therapeutics, Inc. | Detection and quantitation of nucleic acid molecules in biological samples |
| EP2322650A1 (en) * | 2004-05-14 | 2011-05-18 | Rosetta Genomics Ltd | MicroRNAs and uses thereof |
| US8592384B2 (en) * | 2005-04-04 | 2013-11-26 | The Board Of Regents Of The University Of Texas System | Micro-RNA's that regulate muscle cells |
| US20070092882A1 (en) * | 2005-10-21 | 2007-04-26 | Hui Wang | Analysis of microRNA |
| ES2612903T3 (es) * | 2006-01-10 | 2017-05-19 | Koninklijke Nederlandse Akademie Van Wetenschappen | Moléculas de ácido nucleico y colecciones de las mismas, su aplicación e identificación |
| ES2397439T3 (es) * | 2006-08-01 | 2013-03-07 | Board Of Regents Of The University Of Texas System | Identificación de un microARN que activa la expresión de la cadena pesada beta de la miosina |
| US8481507B2 (en) * | 2007-07-31 | 2013-07-09 | The Board Of Regents, The University Of Texas System | Micro-RNAs that control myosin expression and myofiber identity |
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2007
- 2007-12-13 EP EP07867751A patent/EP2104733A2/en not_active Withdrawn
- 2007-12-13 JP JP2009541384A patent/JP2010512747A/ja not_active Withdrawn
- 2007-12-13 US US12/519,323 patent/US20100280094A1/en not_active Abandoned
- 2007-12-13 AU AU2007334502A patent/AU2007334502B2/en not_active Ceased
- 2007-12-13 CN CN2012100499504A patent/CN102604951A/zh active Pending
- 2007-12-13 BR BRPI0719995-3A2A patent/BRPI0719995A2/pt not_active IP Right Cessation
- 2007-12-13 EA EA201101361A patent/EA201101361A1/ru unknown
- 2007-12-13 KR KR1020097012148A patent/KR20090098818A/ko not_active Withdrawn
- 2007-12-13 MX MX2009006310A patent/MX2009006310A/es not_active Application Discontinuation
- 2007-12-13 CA CA002672606A patent/CA2672606A1/en not_active Abandoned
- 2007-12-13 EA EA200900782A patent/EA200900782A1/ru unknown
- 2007-12-13 WO PCT/US2007/025535 patent/WO2008076324A2/en not_active Ceased
- 2007-12-13 CN CNA2007800464358A patent/CN101563458A/zh active Pending
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2011
- 2011-08-09 US US13/206,055 patent/US20120041052A1/en not_active Abandoned
- 2011-08-17 JP JP2011178297A patent/JP2012019789A/ja not_active Withdrawn
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2012
- 2012-01-18 US US13/352,570 patent/US20120114744A1/en not_active Abandoned
- 2012-02-21 JP JP2012034691A patent/JP2012131812A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP2104733A2 (en) | 2009-09-30 |
| EA200900782A1 (ru) | 2009-12-30 |
| MX2009006310A (es) | 2009-07-22 |
| WO2008076324A2 (en) | 2008-06-26 |
| CN102604951A (zh) | 2012-07-25 |
| US20100280094A1 (en) | 2010-11-04 |
| WO2008076324A3 (en) | 2009-04-09 |
| US20120041052A1 (en) | 2012-02-16 |
| JP2012131812A (ja) | 2012-07-12 |
| AU2007334502B2 (en) | 2011-12-15 |
| KR20090098818A (ko) | 2009-09-17 |
| CN101563458A (zh) | 2009-10-21 |
| JP2010512747A (ja) | 2010-04-30 |
| AU2007334502A1 (en) | 2008-06-26 |
| EA201101361A1 (ru) | 2012-11-30 |
| US20120114744A1 (en) | 2012-05-10 |
| BRPI0719995A2 (pt) | 2014-03-18 |
| JP2012019789A (ja) | 2012-02-02 |
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| FZDE | Discontinued |
Effective date: 20131213 |