CA2672606A1 - Compositions and methods to treat muscular & cardiovascular disorders - Google Patents
Compositions and methods to treat muscular & cardiovascular disorders Download PDFInfo
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- CA2672606A1 CA2672606A1 CA002672606A CA2672606A CA2672606A1 CA 2672606 A1 CA2672606 A1 CA 2672606A1 CA 002672606 A CA002672606 A CA 002672606A CA 2672606 A CA2672606 A CA 2672606A CA 2672606 A1 CA2672606 A1 CA 2672606A1
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| US86993706P | 2006-12-14 | 2006-12-14 | |
| US60/869,937 | 2006-12-14 | ||
| PCT/US2007/025535 WO2008076324A2 (en) | 2006-12-14 | 2007-12-13 | Compositions and methods to treat muscular & cardiovascular disorders |
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| CA2672606A1 true CA2672606A1 (en) | 2008-06-26 |
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| CA002672606A Abandoned CA2672606A1 (en) | 2006-12-14 | 2007-12-13 | Compositions and methods to treat muscular & cardiovascular disorders |
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| JP (3) | JP2010512747A (enExample) |
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| CN (2) | CN102604951A (enExample) |
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| EA (2) | EA201101361A1 (enExample) |
| MX (1) | MX2009006310A (enExample) |
| WO (1) | WO2008076324A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2434017A3 (en) | 2006-08-01 | 2012-09-05 | Board of Regents of the University of Texas System | Identification of a micro-RNA that activates expression of beta-myosin heavy chain |
| WO2009018492A2 (en) | 2007-07-31 | 2009-02-05 | The Board Of Regents Of The University Of Texas System | Micro-rnas that control myosin expression and myofiber identity |
| MX2011008190A (es) * | 2009-02-04 | 2011-10-06 | Univ Texas | Direccionamiento dual de mir-208 y mir-499 en el tratamiento de trastornos cardiacos. |
| IE20090047A1 (en) * | 2009-02-26 | 2010-09-29 | Nat Univ Ireland | Protein targets in disease |
| JP5757885B2 (ja) * | 2009-03-12 | 2015-08-05 | ブランディーズ・ユニバーシティ | Ｐｃｒ用の試薬および方法 |
| US8642751B2 (en) | 2010-12-15 | 2014-02-04 | Miragen Therapeutics | MicroRNA inhibitors comprising locked nucleotides |
| US9428749B2 (en) | 2011-10-06 | 2016-08-30 | The Board Of Regents, The University Of Texas System | Control of whole body energy homeostasis by microRNA regulation |
| JP6208228B2 (ja) | 2012-06-21 | 2017-10-04 | ミラゲン セラピューティクス， インコーポレイテッド | ロックド核酸モチーフを含むオリゴヌクレオチドベースの阻害剤 |
| US10577604B2 (en) | 2012-10-15 | 2020-03-03 | Ionis Pharmaceuticals, Inc. | Methods for monitoring C9ORF72 expression |
| BR112015008399A8 (pt) * | 2012-10-15 | 2017-10-03 | Ionis Pharmaceuticals Inc | Composto para modular a expressão de c90rf72, seu uso, oligonucleotídeo modificado, composto de fita dupla e composição |
| WO2014169126A1 (en) * | 2013-04-10 | 2014-10-16 | Reveragen Biopharma, Inc. | Methods and agents to increase therapeutic dystrophin expression in muscle |
| MY192689A (en) | 2013-10-11 | 2022-09-01 | Ionis Pharmaceuticals Inc | Compositions for modulating c9orf72 expression |
| AU2015301221B2 (en) * | 2014-08-04 | 2020-07-02 | MiRagen Therapeutics, Inc. | Inhibitors of MYH7B and uses thereof |
| EP3247716A4 (en) | 2015-01-20 | 2018-10-17 | Miragen Therapeutics, Inc. | Mir-92 inhibitors and uses thereof |
| JP6606557B2 (ja) | 2015-04-16 | 2019-11-13 | アイオーニス ファーマシューティカルズ， インコーポレーテッド | Ｃ９ｏｒｆ７２発現を調節するための組成物 |
| US11260073B2 (en) | 2015-11-02 | 2022-03-01 | Ionis Pharmaceuticals, Inc. | Compounds and methods for modulating C90RF72 |
| CN106148519A (zh) * | 2016-07-05 | 2016-11-23 | 无锡市第二人民医院 | 一种microRNA‑499的快速检测方法 |
| WO2019014656A1 (en) | 2017-07-14 | 2019-01-17 | Han Si Ping | METALLIC OLIGONUCLEOTIDE JONCTIONS FOR THE ADMINISTRATION OF THERAPEUTIC AGENTS |
| EP3665281A4 (en) * | 2017-08-10 | 2021-05-05 | City of Hope | CONDITIONAL SIRNA AND ITS USE IN THE TREATMENT OF CARDIAC HYERTROPHY |
| KR102281710B1 (ko) | 2021-02-19 | 2021-07-28 | 조기정 | 에어튜브를 이용한 선박 안전장치 |
| CN119246849B (zh) * | 2024-12-09 | 2025-03-14 | 上海基灵生物科技有限公司 | 一种检测犬心脏损伤的试剂盒及应用 |
Family Cites Families (16)
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| US5602240A (en) * | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| US5489677A (en) * | 1990-07-27 | 1996-02-06 | Isis Pharmaceuticals, Inc. | Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms |
| KR100211552B1 (ko) * | 1990-08-03 | 1999-08-02 | 디. 꼬쉬 | 유전자 발현 억제용 화합물 및 방법 |
| US5719262A (en) * | 1993-11-22 | 1998-02-17 | Buchardt, Deceased; Ole | Peptide nucleic acids having amino acid side chains |
| US5700922A (en) * | 1991-12-24 | 1997-12-23 | Isis Pharmaceuticals, Inc. | PNA-DNA-PNA chimeric macromolecules |
| JP3516167B2 (ja) * | 1992-12-08 | 2004-04-05 | ローム株式会社 | タンタルコンデンサチップの製造方法 |
| US6271359B1 (en) * | 1999-04-14 | 2001-08-07 | Musc Foundation For Research Development | Tissue-specific and pathogen-specific toxic agents and ribozymes |
| RU2322500C2 (ru) * | 2000-12-01 | 2008-04-20 | Макс-Планк-Гезелльшафт Цур Фердерунг Дер Виссеншафтен Е.Ф. | Малые молекулы рнк, опосредующие интерференцию рнк |
| SG190613A1 (en) * | 2003-07-16 | 2013-06-28 | Protiva Biotherapeutics Inc | Lipid encapsulated interfering rna |
| US7521184B2 (en) * | 2003-08-22 | 2009-04-21 | Sirna Therapeutics, Inc. | Detection and quantitation of nucleic acid molecules in biological samples |
| JP5697297B2 (ja) * | 2004-05-14 | 2015-04-08 | ロゼッタ ジノミクス リミテッド | マイクロｎａｓおよびその使用 |
| WO2006107826A2 (en) * | 2005-04-04 | 2006-10-12 | The Board Of Regents Of The University Of Texas System | Micro-rna's that regulate muscle cells |
| US20070092882A1 (en) * | 2005-10-21 | 2007-04-26 | Hui Wang | Analysis of microRNA |
| EP2402463B1 (en) * | 2006-01-10 | 2016-11-09 | Koninklijke Nederlandse Akademie van Wetenschappen | Nucleic acid molecules and collections thereof, their application and identification |
| EP2434017A3 (en) * | 2006-08-01 | 2012-09-05 | Board of Regents of the University of Texas System | Identification of a micro-RNA that activates expression of beta-myosin heavy chain |
| WO2009018492A2 (en) * | 2007-07-31 | 2009-02-05 | The Board Of Regents Of The University Of Texas System | Micro-rnas that control myosin expression and myofiber identity |
-
2007
- 2007-12-13 US US12/519,323 patent/US20100280094A1/en not_active Abandoned
- 2007-12-13 MX MX2009006310A patent/MX2009006310A/es not_active Application Discontinuation
- 2007-12-13 CA CA002672606A patent/CA2672606A1/en not_active Abandoned
- 2007-12-13 BR BRPI0719995-3A2A patent/BRPI0719995A2/pt not_active IP Right Cessation
- 2007-12-13 EA EA201101361A patent/EA201101361A1/ru unknown
- 2007-12-13 EP EP07867751A patent/EP2104733A2/en not_active Withdrawn
- 2007-12-13 WO PCT/US2007/025535 patent/WO2008076324A2/en not_active Ceased
- 2007-12-13 AU AU2007334502A patent/AU2007334502B2/en not_active Ceased
- 2007-12-13 JP JP2009541384A patent/JP2010512747A/ja not_active Withdrawn
- 2007-12-13 KR KR1020097012148A patent/KR20090098818A/ko not_active Withdrawn
- 2007-12-13 EA EA200900782A patent/EA200900782A1/ru unknown
- 2007-12-13 CN CN2012100499504A patent/CN102604951A/zh active Pending
- 2007-12-13 CN CNA2007800464358A patent/CN101563458A/zh active Pending
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2011
- 2011-08-09 US US13/206,055 patent/US20120041052A1/en not_active Abandoned
- 2011-08-17 JP JP2011178297A patent/JP2012019789A/ja not_active Withdrawn
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2012
- 2012-01-18 US US13/352,570 patent/US20120114744A1/en not_active Abandoned
- 2012-02-21 JP JP2012034691A patent/JP2012131812A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EA201101361A1 (ru) | 2012-11-30 |
| WO2008076324A3 (en) | 2009-04-09 |
| US20120041052A1 (en) | 2012-02-16 |
| WO2008076324A2 (en) | 2008-06-26 |
| CN102604951A (zh) | 2012-07-25 |
| AU2007334502B2 (en) | 2011-12-15 |
| MX2009006310A (es) | 2009-07-22 |
| JP2012131812A (ja) | 2012-07-12 |
| EA200900782A1 (ru) | 2009-12-30 |
| EP2104733A2 (en) | 2009-09-30 |
| CN101563458A (zh) | 2009-10-21 |
| US20100280094A1 (en) | 2010-11-04 |
| JP2012019789A (ja) | 2012-02-02 |
| KR20090098818A (ko) | 2009-09-17 |
| AU2007334502A1 (en) | 2008-06-26 |
| JP2010512747A (ja) | 2010-04-30 |
| US20120114744A1 (en) | 2012-05-10 |
| BRPI0719995A2 (pt) | 2014-03-18 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20131213 |