CA2672606A1 - Compositions and methods to treat muscular & cardiovascular disorders - Google Patents
Compositions and methods to treat muscular & cardiovascular disorders Download PDFInfo
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- CA2672606A1 CA2672606A1 CA002672606A CA2672606A CA2672606A1 CA 2672606 A1 CA2672606 A1 CA 2672606A1 CA 002672606 A CA002672606 A CA 002672606A CA 2672606 A CA2672606 A CA 2672606A CA 2672606 A1 CA2672606 A1 CA 2672606A1
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| PCT/US2007/025535 WO2008076324A2 (en) | 2006-12-14 | 2007-12-13 | Compositions and methods to treat muscular & cardiovascular disorders |
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Families Citing this family (21)
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| ES2397439T3 (es) | 2006-08-01 | 2013-03-07 | Board Of Regents Of The University Of Texas System | Identificación de un microARN que activa la expresión de la cadena pesada beta de la miosina |
| CN101808649B (zh) | 2007-07-31 | 2014-05-21 | 得克萨斯系统大学董事会 | 控制肌球蛋白表达和肌纤维身份的微小rna |
| MX2011008190A (es) * | 2009-02-04 | 2011-10-06 | Univ Texas | Direccionamiento dual de mir-208 y mir-499 en el tratamiento de trastornos cardiacos. |
| IE20090047A1 (en) * | 2009-02-26 | 2010-09-29 | Nat Univ Ireland | Protein targets in disease |
| AU2010224100B2 (en) * | 2009-03-12 | 2015-10-22 | Brandeis University | Reagents and methods for PCR |
| AU2011343720A1 (en) | 2010-12-15 | 2013-04-11 | Miragen Therapeutics | MicroRNA inhibitors comprising locked nucleotides |
| CA2850223A1 (en) | 2011-10-06 | 2013-04-11 | Eva Van Rooij | Control of whole body energy homeostasis by microrna regulation |
| HK1209781A1 (en) | 2012-06-21 | 2016-04-08 | MiRagen Therapeutics, Inc. | Oligonucleotide-based inhibitors comprising locked nucleic acid motif |
| WO2014062691A2 (en) * | 2012-10-15 | 2014-04-24 | Isis Pharmaceuticals, Inc. | Compositions for modulating c9orf72 expression |
| EP2906697A4 (en) | 2012-10-15 | 2016-06-22 | Ionis Pharmaceuticals Inc | METHOD FOR MONITORING THE C9ORF72 EXPRESSION |
| WO2014169126A1 (en) * | 2013-04-10 | 2014-10-16 | Reveragen Biopharma, Inc. | Methods and agents to increase therapeutic dystrophin expression in muscle |
| CN112080502A (zh) | 2013-10-11 | 2020-12-15 | Ionis制药公司 | 用于调节c9orf72表达的组合物 |
| WO2016022536A2 (en) * | 2014-08-04 | 2016-02-11 | MiRagen Therapeutics, Inc. | Inhibitors of myh7b and uses thereof |
| BR112017015618A2 (pt) | 2015-01-20 | 2018-04-10 | Miragen Therapeutics Inc | inibidores de mir-92 e usos destes. |
| PL3283080T3 (pl) | 2015-04-16 | 2020-07-27 | Ionis Pharmaceuticals, Inc. | Kompozycja do modulowania ekspresji c9orf72 |
| US11260073B2 (en) | 2015-11-02 | 2022-03-01 | Ionis Pharmaceuticals, Inc. | Compounds and methods for modulating C90RF72 |
| CN106148519A (zh) * | 2016-07-05 | 2016-11-23 | 无锡市第二人民医院 | 一种microRNA‑499的快速检测方法 |
| US12054711B2 (en) | 2017-07-14 | 2024-08-06 | City Of Hope | Meta-stable oligonucleotides junctions for delivery of therapeutics |
| EP3665281A4 (en) * | 2017-08-10 | 2021-05-05 | City of Hope | CONDITIONAL SIRNA AND ITS USE IN THE TREATMENT OF CARDIAC HYERTROPHY |
| KR102281710B1 (ko) | 2021-02-19 | 2021-07-28 | 조기정 | 에어튜브를 이용한 선박 안전장치 |
| CN119246849B (zh) * | 2024-12-09 | 2025-03-14 | 上海基灵生物科技有限公司 | 一种检测犬心脏损伤的试剂盒及应用 |
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| US5489677A (en) * | 1990-07-27 | 1996-02-06 | Isis Pharmaceuticals, Inc. | Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms |
| US5602240A (en) * | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| IL113519A (en) * | 1990-08-03 | 1997-11-20 | Sterling Winthrop Inc | Oligonucleoside sequences of from about 6 to about 200 bases having a three atom internucleoside linkage, their preparation and pharmaceutical compositions for inhibiting gene expression containing said oligonucleosides |
| US5719262A (en) * | 1993-11-22 | 1998-02-17 | Buchardt, Deceased; Ole | Peptide nucleic acids having amino acid side chains |
| US5700922A (en) * | 1991-12-24 | 1997-12-23 | Isis Pharmaceuticals, Inc. | PNA-DNA-PNA chimeric macromolecules |
| JP3516167B2 (ja) * | 1992-12-08 | 2004-04-05 | ローム株式会社 | タンタルコンデンサチップの製造方法 |
| US6271359B1 (en) * | 1999-04-14 | 2001-08-07 | Musc Foundation For Research Development | Tissue-specific and pathogen-specific toxic agents and ribozymes |
| EP1873259B1 (en) * | 2000-12-01 | 2012-01-25 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | RNA interference mediated by 21 and 22nt RNAs |
| JP4951338B2 (ja) * | 2003-07-16 | 2012-06-13 | プロチバ バイオセラピューティクス インコーポレイティッド | 脂質に封入された干渉ｒｎａ |
| WO2005021800A2 (en) * | 2003-08-22 | 2005-03-10 | Sirna Therapeutics, Inc. | Detection and quantitation of nucleic acid molecules in biological samples |
| WO2005111211A2 (en) * | 2004-05-14 | 2005-11-24 | Rosetta Genomics Ltd. | Micronas and uses thereof |
| CA2603881A1 (en) * | 2005-04-04 | 2006-10-12 | The Board Of Regents Of The University Of Texas System | Micro-rna's that regulate muscle cells |
| US20070092882A1 (en) * | 2005-10-21 | 2007-04-26 | Hui Wang | Analysis of microRNA |
| JP2009523013A (ja) * | 2006-01-10 | 2009-06-18 | コニンクリユケ ネーデルランドセ アカデミ ファン ウェテンスハッペン | 新規な核酸分子及びそのコレクション、並びにそれらの用途及び同定方法 |
| ES2397439T3 (es) * | 2006-08-01 | 2013-03-07 | Board Of Regents Of The University Of Texas System | Identificación de un microARN que activa la expresión de la cadena pesada beta de la miosina |
| CN101808649B (zh) * | 2007-07-31 | 2014-05-21 | 得克萨斯系统大学董事会 | 控制肌球蛋白表达和肌纤维身份的微小rna |
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2007
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- 2007-12-13 MX MX2009006310A patent/MX2009006310A/es not_active Application Discontinuation
- 2007-12-13 AU AU2007334502A patent/AU2007334502B2/en not_active Ceased
- 2007-12-13 EA EA201101361A patent/EA201101361A1/ru unknown
- 2007-12-13 EP EP07867751A patent/EP2104733A2/en not_active Withdrawn
- 2007-12-13 US US12/519,323 patent/US20100280094A1/en not_active Abandoned
- 2007-12-13 KR KR1020097012148A patent/KR20090098818A/ko not_active Withdrawn
- 2007-12-13 EA EA200900782A patent/EA200900782A1/ru unknown
- 2007-12-13 CA CA002672606A patent/CA2672606A1/en not_active Abandoned
- 2007-12-13 BR BRPI0719995-3A2A patent/BRPI0719995A2/pt not_active IP Right Cessation
- 2007-12-13 WO PCT/US2007/025535 patent/WO2008076324A2/en not_active Ceased
- 2007-12-13 JP JP2009541384A patent/JP2010512747A/ja not_active Withdrawn
- 2007-12-13 CN CN2012100499504A patent/CN102604951A/zh active Pending
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2011
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- 2011-08-17 JP JP2011178297A patent/JP2012019789A/ja not_active Withdrawn
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2012
- 2012-01-18 US US13/352,570 patent/US20120114744A1/en not_active Abandoned
- 2012-02-21 JP JP2012034691A patent/JP2012131812A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CN102604951A (zh) | 2012-07-25 |
| AU2007334502B2 (en) | 2011-12-15 |
| JP2010512747A (ja) | 2010-04-30 |
| WO2008076324A3 (en) | 2009-04-09 |
| JP2012019789A (ja) | 2012-02-02 |
| JP2012131812A (ja) | 2012-07-12 |
| EA201101361A1 (ru) | 2012-11-30 |
| MX2009006310A (es) | 2009-07-22 |
| EP2104733A2 (en) | 2009-09-30 |
| AU2007334502A1 (en) | 2008-06-26 |
| BRPI0719995A2 (pt) | 2014-03-18 |
| US20100280094A1 (en) | 2010-11-04 |
| EA200900782A1 (ru) | 2009-12-30 |
| US20120114744A1 (en) | 2012-05-10 |
| WO2008076324A2 (en) | 2008-06-26 |
| KR20090098818A (ko) | 2009-09-17 |
| CN101563458A (zh) | 2009-10-21 |
| US20120041052A1 (en) | 2012-02-16 |
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