CA2664418A1 - Muteines de l'interleukine-1 liees a des particules de type viral destinees au traitement de maladies associees a l'il-1 - Google Patents

Muteines de l'interleukine-1 liees a des particules de type viral destinees au traitement de maladies associees a l'il-1 Download PDF

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Publication number
CA2664418A1
CA2664418A1 CA002664418A CA2664418A CA2664418A1 CA 2664418 A1 CA2664418 A1 CA 2664418A1 CA 002664418 A CA002664418 A CA 002664418A CA 2664418 A CA2664418 A CA 2664418A CA 2664418 A1 CA2664418 A1 CA 2664418A1
Authority
CA
Canada
Prior art keywords
seq
amino acid
acid sequence
composition
mutein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002664418A
Other languages
English (en)
Inventor
Martin Bachmann
Gunther Spohn
Alain Tissot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytos Biotechnology AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2006/066866 external-priority patent/WO2007039552A1/fr
Application filed by Individual filed Critical Individual
Publication of CA2664418A1 publication Critical patent/CA2664418A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/545IL-1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/18011Details ssRNA Bacteriophages positive-sense
    • C12N2795/18111Leviviridae
    • C12N2795/18123Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002664418A 2006-09-28 2007-03-29 Muteines de l'interleukine-1 liees a des particules de type viral destinees au traitement de maladies associees a l'il-1 Abandoned CA2664418A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/EP2006/066866 WO2007039552A1 (fr) 2005-09-28 2006-09-28 Conjugés d’interleukin-1 et leurs utilisations
EPPCT/EP2006/066866 2006-09-28
PCT/EP2007/053007 WO2008037504A1 (fr) 2006-09-28 2007-03-29 Mutéines de l'interleukine-1 liées à des particules de type viral destinées au traitement de maladies associées à l'il-1

Publications (1)

Publication Number Publication Date
CA2664418A1 true CA2664418A1 (fr) 2008-04-03

Family

ID=38169456

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002664418A Abandoned CA2664418A1 (fr) 2006-09-28 2007-03-29 Muteines de l'interleukine-1 liees a des particules de type viral destinees au traitement de maladies associees a l'il-1

Country Status (4)

Country Link
EP (1) EP2066347A1 (fr)
AU (1) AU2007302198A1 (fr)
CA (1) CA2664418A1 (fr)
WO (1) WO2008037504A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008500364A (ja) 2004-05-25 2008-01-10 キメラコア, インコーポレイテッド 自己集合性ナノ粒子薬物送達システム
WO2008108776A1 (fr) 2006-04-07 2008-09-12 Chimeros, Inc. Compositions et procédés visant à traiter des malignités de cellules b
US20110318300A1 (en) * 2008-03-05 2011-12-29 Cytos Biotechnology Ag User of Interleukin-1 Conjugates in the Treatment of Diabetes
WO2010120874A2 (fr) 2009-04-14 2010-10-21 Chimeros, Inc. Agents thérapeutiques chimériques, compositions, et leurs procédés d'utilisation
AU2010294249A1 (en) 2009-09-10 2012-05-03 Cytos Biotechnology Ag Use of interleukin-1 beta mutein conjugates in the treatment of diabetes
JP2014527072A (ja) 2011-09-09 2014-10-09 バイオメド リアルティー, エル.ピー. ウイルスタンパク質の集合を制御するための方法および組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5171890A (en) * 1989-02-27 1990-09-26 Massachusetts Institute Of Technology Il-1 biological activity inhibitors
ATE413191T1 (de) * 1999-12-03 2008-11-15 Celltech Chiroscience Ltd Verwendung of interleukin-1 mutein als impfstoffadjuvans
MXPA05000277A (es) * 2002-07-17 2005-03-31 Cytos Biotechnology Ag Configuraciones de antigenos moleculares de usan una particula tipo virus derivada de la proteina de recurimiento ap205.

Also Published As

Publication number Publication date
EP2066347A1 (fr) 2009-06-10
AU2007302198A1 (en) 2008-04-03
WO2008037504A1 (fr) 2008-04-03

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BACHMANN et al. Patent 2717108 Summary

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20150123