CA2662597A1 - Biomarkers for assessing liver function - Google Patents

Biomarkers for assessing liver function Download PDF

Info

Publication number
CA2662597A1
CA2662597A1 CA002662597A CA2662597A CA2662597A1 CA 2662597 A1 CA2662597 A1 CA 2662597A1 CA 002662597 A CA002662597 A CA 002662597A CA 2662597 A CA2662597 A CA 2662597A CA 2662597 A1 CA2662597 A1 CA 2662597A1
Authority
CA
Canada
Prior art keywords
individual
liver
patients
liver disease
adma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002662597A
Other languages
English (en)
French (fr)
Inventor
Rajiv Jalan
Rajeshwar P. Mookerjee
Nathan Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCL Business Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2662597A1 publication Critical patent/CA2662597A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/76Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
    • G01N2333/765Serum albumin, e.g. HSA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/08Hepato-biliairy disorders other than hepatitis
    • G01N2800/085Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
CA002662597A 2006-09-07 2007-09-07 Biomarkers for assessing liver function Abandoned CA2662597A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0617581.4 2006-09-07
GBGB0617581.4A GB0617581D0 (en) 2006-09-07 2006-09-07 Biomarkers for assessing liver function
PCT/GB2007/003362 WO2008029145A1 (en) 2006-09-07 2007-09-07 Biqmarkers for assessing liver function

Publications (1)

Publication Number Publication Date
CA2662597A1 true CA2662597A1 (en) 2008-03-13

Family

ID=37232490

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002662597A Abandoned CA2662597A1 (en) 2006-09-07 2007-09-07 Biomarkers for assessing liver function

Country Status (16)

Country Link
US (1) US8455220B2 (cg-RX-API-DMAC7.html)
EP (1) EP2059817B1 (cg-RX-API-DMAC7.html)
JP (1) JP4949473B2 (cg-RX-API-DMAC7.html)
KR (1) KR20090083335A (cg-RX-API-DMAC7.html)
AT (1) ATE488772T1 (cg-RX-API-DMAC7.html)
AU (1) AU2007293302A1 (cg-RX-API-DMAC7.html)
CA (1) CA2662597A1 (cg-RX-API-DMAC7.html)
DE (1) DE602007010644D1 (cg-RX-API-DMAC7.html)
EA (1) EA200970256A1 (cg-RX-API-DMAC7.html)
ES (1) ES2353835T3 (cg-RX-API-DMAC7.html)
GB (1) GB0617581D0 (cg-RX-API-DMAC7.html)
IL (1) IL197271A0 (cg-RX-API-DMAC7.html)
MX (1) MX2009002378A (cg-RX-API-DMAC7.html)
NO (1) NO20090993L (cg-RX-API-DMAC7.html)
WO (1) WO2008029145A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200901432B (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012262329B2 (en) 2011-05-31 2014-10-16 The Regents Of The University Of Colorado, A Body Corporate Method for assessment of hepatic function and portal blood flow
CA3191764A1 (en) * 2012-11-12 2014-05-15 The Regents Of The University Of Colorado, A Body Corporate Disease severity index for assessment of chronic liver disease and method for diagnosis of three distinct subtypes of primary sclerosing cholangitis
US10054600B2 (en) 2013-05-22 2018-08-21 The Regents Of The University Of California Biomarker composite test for hepatic vein pressure gradient and cirrhosis treatment
CA2965325A1 (en) * 2014-10-24 2016-04-28 Mallinckrodt Hospital Products IP Limited Method of treating patients with hepatorenal syndrome type 1
CN105181692A (zh) * 2015-09-30 2015-12-23 山东博科生物产业有限公司 一种缺血修饰白蛋白比色法检测试剂盒
US10793909B2 (en) 2015-11-10 2020-10-06 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for predicting the survival time of patients with decompensated alcoholic cirrhosis
US20220018852A1 (en) * 2018-11-20 2022-01-20 Inserm (Institute National De Ka Santé Et De La Recherche Médicale) Methods and kits for detecting liver dysfunction in a subject

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034605A1 (en) 1996-03-21 1997-09-25 Mayo Foundation For Medical Education And Research Use of nicotine to treat liver disease
AU2001275870A1 (en) 2000-07-06 2002-01-21 Fal Diagnostics Methods and kits for the detection of arginine compounds
US7063782B2 (en) * 2001-11-26 2006-06-20 Ischemia Technologies, Inc. Electrochemical detection of ischemia
WO2004012686A2 (en) * 2002-08-06 2004-02-12 Nitromed, Inc. Nitrosated and/or nitrosylated ursodeoxycholic acid compounds, compositions and methods of use
WO2004046314A2 (en) 2002-11-15 2004-06-03 The Board Of Trustees Of The Leland Stanford Junior University Methods for detecting asymmetric dimethylarginine in a biological sample
WO2005039598A1 (en) * 2003-10-24 2005-05-06 Intermune, Inc. Method of treating alcoholic liver disease
DE10351238A1 (de) * 2003-11-03 2005-06-02 Roche Diagnostics Gmbh Diagnosestellung von akuten myokardialen, ischämischen Erkrankungen durch Kombination von Markern

Also Published As

Publication number Publication date
WO2008029145A1 (en) 2008-03-13
DE602007010644D1 (de) 2010-12-30
EP2059817A1 (en) 2009-05-20
ZA200901432B (en) 2010-06-30
IL197271A0 (en) 2009-12-24
KR20090083335A (ko) 2009-08-03
AU2007293302A1 (en) 2008-03-13
JP4949473B2 (ja) 2012-06-06
NO20090993L (no) 2009-04-03
US20090280519A1 (en) 2009-11-12
EP2059817B1 (en) 2010-11-17
GB0617581D0 (en) 2006-10-18
ES2353835T3 (es) 2011-03-07
EA200970256A1 (ru) 2009-08-28
MX2009002378A (es) 2009-03-20
JP2010502979A (ja) 2010-01-28
ATE488772T1 (de) 2010-12-15
US8455220B2 (en) 2013-06-04

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20120907