CA2659425C - Triazole compounds that modulate hsp90 activity - Google Patents

Triazole compounds that modulate hsp90 activity Download PDF

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Publication number
CA2659425C
CA2659425C CA2659425A CA2659425A CA2659425C CA 2659425 C CA2659425 C CA 2659425C CA 2659425 A CA2659425 A CA 2659425A CA 2659425 A CA2659425 A CA 2659425A CA 2659425 C CA2659425 C CA 2659425C
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Canada
Prior art keywords
optionally substituted
triazole
mercapto
dihydroxy
nr10r11
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CA2659425A
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English (en)
French (fr)
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CA2659425A1 (en
Inventor
Kevin Foley
Weiwen Ying
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Synta Phamaceuticals Corp
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Synta Phamaceuticals Corp
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
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CA2659425A 2006-08-17 2007-08-14 Triazole compounds that modulate hsp90 activity Active CA2659425C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83830606P 2006-08-17 2006-08-17
US60/838,306 2006-08-17
PCT/US2007/017996 WO2008021364A2 (en) 2006-08-17 2007-08-14 Triazole compounds that modulate hsp90 activity

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CA2659425A1 CA2659425A1 (en) 2008-02-21
CA2659425C true CA2659425C (en) 2017-06-20

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CA2659425A Active CA2659425C (en) 2006-08-17 2007-08-14 Triazole compounds that modulate hsp90 activity

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US (1) US8188075B2 (OSRAM)
EP (1) EP2054059A2 (OSRAM)
JP (1) JP5480623B2 (OSRAM)
AU (1) AU2007284537B2 (OSRAM)
CA (1) CA2659425C (OSRAM)
WO (1) WO2008021364A2 (OSRAM)

Families Citing this family (40)

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Publication number Priority date Publication date Assignee Title
PT1817295E (pt) * 2004-11-18 2013-02-18 Synta Pharmaceuticals Corp Compostos de triazol que modulam a actividade da hsp90
CA2618377A1 (en) 2005-08-12 2007-02-22 Synta Pharmaceuticals Corp. Pyrazole compounds that modulate hsp90 activity
CA2618628C (en) 2005-08-18 2014-11-18 Synta Pharmaceuticals Corp. Triazole compounds that modulate hsp90 activity
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