CA2658463C - Methode efficace de reprogrammation nucleaire - Google Patents
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- CA2658463C CA2658463C CA2658463A CA2658463A CA2658463C CA 2658463 C CA2658463 C CA 2658463C CA 2658463 A CA2658463 A CA 2658463A CA 2658463 A CA2658463 A CA 2658463A CA 2658463 C CA2658463 C CA 2658463C
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
L'invention concerne un procédé pour produire efficacement des cellules souches pluripotentes artificielles qui comprend l'étape consistant à procéder à une initialisation de noyaux au moyen d'un facteur d'initialisation de noyaux en présence d'un miARN, le miARN ayant les caractéristiques suivantes : (a) il est exprimé dans les cellules souches embryonnaires à un plus haut niveau que dans les cellules somatiques ; et (b) une efficacité d'initialisation de noyaux plus élevée a été établie en présence du miARN qu'en son absence.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99689307P | 2007-12-10 | 2007-12-10 | |
| US60/996,893 | 2007-12-10 | ||
| PCT/JP2008/059586 WO2009075119A1 (fr) | 2007-12-10 | 2008-05-23 | Procédé efficace d'initialisation de noyaux |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2658463A1 CA2658463A1 (fr) | 2009-06-10 |
| CA2658463C true CA2658463C (fr) | 2015-07-21 |
Family
ID=40751190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2658463A Active CA2658463C (fr) | 2007-12-10 | 2008-05-23 | Methode efficace de reprogrammation nucleaire |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2658463C (fr) |
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2008
- 2008-05-23 CA CA2658463A patent/CA2658463C/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2658463A1 (fr) | 2009-06-10 |
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| EEER | Examination request |
Effective date: 20130515 |