CA2644013C - Medicament magazine for an inhaler, and a multi-dose powder inhaler - Google Patents

Medicament magazine for an inhaler, and a multi-dose powder inhaler Download PDF

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Publication number
CA2644013C
CA2644013C CA2644013A CA2644013A CA2644013C CA 2644013 C CA2644013 C CA 2644013C CA 2644013 A CA2644013 A CA 2644013A CA 2644013 A CA2644013 A CA 2644013A CA 2644013 C CA2644013 C CA 2644013C
Authority
CA
Canada
Prior art keywords
internal structure
medicament
foil
magazine
cutting edge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2644013A
Other languages
English (en)
French (fr)
Other versions
CA2644013A1 (en
Inventor
Herbert Wachtel
Johannes Geser
Burkhard P. Metzger
Michael Spallek
Michael Krueger
Hubert Kunze
Achim Moser
Elmar Mock
Antonino Lanci
Andre Klopfenstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of CA2644013A1 publication Critical patent/CA2644013A1/en
Application granted granted Critical
Publication of CA2644013C publication Critical patent/CA2644013C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0061—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using pre-packed dosages having an insert inside
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CA2644013A 2006-04-13 2007-04-13 Medicament magazine for an inhaler, and a multi-dose powder inhaler Active CA2644013C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06405163.4 2006-04-13
EP06405163A EP1844809A1 (de) 2006-04-13 2006-04-13 Medikamentenmagazin für einen Inhalator, sowie Mehrdosispulverinhalator
PCT/CH2007/000180 WO2007118342A2 (de) 2006-04-13 2007-04-13 Medikamentenmagazin für einen inhalator, sowie mehrdosispulverinhalator

Publications (2)

Publication Number Publication Date
CA2644013A1 CA2644013A1 (en) 2007-10-25
CA2644013C true CA2644013C (en) 2015-03-17

Family

ID=36942292

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2644013A Active CA2644013C (en) 2006-04-13 2007-04-13 Medicament magazine for an inhaler, and a multi-dose powder inhaler

Country Status (5)

Country Link
US (1) US8267082B2 (OSRAM)
EP (2) EP1844809A1 (OSRAM)
JP (1) JP2009533097A (OSRAM)
CA (1) CA2644013C (OSRAM)
WO (1) WO2007118342A2 (OSRAM)

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US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
EP1494732B1 (en) 2002-03-20 2008-01-30 MannKind Corporation Inhalation apparatus
US7861712B2 (en) * 2004-04-23 2011-01-04 Manta Product Development Sealed capsule including an integrated puncturing mechanism
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
AU2006290227B2 (en) 2005-09-14 2012-08-02 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
US20070214794A1 (en) * 2006-03-15 2007-09-20 Tweeton Erik H Supercharged subsonic rotary ramjet turbine with vibration free piston air compressor
DE102006014434A1 (de) * 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Packmittel für Mehrdosispulverinhalatoren mit optimierten Entleerungseigenschaften
BRPI0806474A2 (pt) 2007-01-09 2011-09-27 Mystic Pharmaceuticals Inc dispositivos de cartucho intranasal
US9248076B2 (en) 2007-05-16 2016-02-02 Mystic Pharmaceuticals, Inc. Dose dispensing containers
EP2898914B1 (en) 2007-07-06 2018-06-20 Manta Devices, LLC Inhalation devices for storing and delivering medicament
US11224704B2 (en) 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
GB0800708D0 (en) * 2008-01-16 2008-02-20 Dunne Stephen T Atomising device
SG10201507036TA (en) 2008-06-13 2015-10-29 Mannkind Corp A dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
WO2010021589A1 (en) * 2008-08-20 2010-02-25 Astrazeneca Ab Inhaler
CA2742832A1 (en) * 2008-11-06 2010-05-14 Medispray Laboratories Pvt. Ltd Inhaler device
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8550074B2 (en) 2009-01-15 2013-10-08 Manta Devices, Llc Delivery device and related methods
MX2011009512A (es) 2009-03-11 2011-11-29 Mannkind Corp Aparato, sistema y metodo para medir la resistencia de un inhalador.
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
WO2011116293A2 (en) 2010-03-19 2011-09-22 Manta Devices, Llc Delivery device and related methods
IL223742A (en) 2010-06-21 2016-06-30 Mannkind Corp A dry powder inhaler and preparation for it
EP2694402B1 (en) 2011-04-01 2017-03-22 MannKind Corporation Blister package for pharmaceutical cartridges
US8585659B2 (en) * 2011-05-31 2013-11-19 Mystic Pharmaceuticals, Inc. Piercing device for drug delivery systems
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US11103659B2 (en) 2011-07-06 2021-08-31 Manta Devices, Llc Delivery device and related methods
HK1200318A1 (en) 2011-10-24 2015-08-07 曼金德公司 Methods and compositions for treating pain
TW201340894A (zh) * 2011-12-20 2013-10-16 British American Tobacco Co 吸煙物件及其他氣流輸送物件（二）
US9649454B2 (en) 2012-05-03 2017-05-16 Manta Devices, Llc Delivery device and related methods
EP2872205B1 (en) * 2012-07-12 2017-02-08 MannKind Corporation Dry powder drug delivery systems
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
GB201301192D0 (en) * 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
KR102465025B1 (ko) 2013-07-18 2022-11-09 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
DE14853999T1 (de) 2013-10-15 2017-02-16 Jesse, Ryan Hancock Verwirbelungsdüse mit steuerbarer geschwindigkeit
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
EP3137140B1 (en) 2014-05-02 2019-07-10 Manta Devices, LLC Delivery device
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
JP7376336B2 (ja) * 2019-12-11 2023-11-08 株式会社京都製作所 包装体開封システム
WO2023186758A1 (en) * 2022-03-28 2023-10-05 Astrazeneca Ab Dry powder formulation inhaler and capsule

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NL192564C (nl) * 1982-10-08 1997-10-03 Glaxo Group Ltd Inrichting voor het toedienen van medicamenten aan patiënten.
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
DK544589D0 (da) * 1989-11-01 1989-11-01 Novo Nordisk As Manuel betjent apparat til dispensering af en forudbestemt maengde af et pulverformet stof
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
ES2089474T3 (es) * 1991-08-16 1996-10-01 Sandoz Ltd Inhalador para la administracion de sustancias en polvo.
GB9203761D0 (en) * 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
US5896855A (en) * 1992-12-24 1999-04-27 Rhone-Poulenc Rorer Limited Multi dose inhaler apparatus
DE4400083C2 (de) * 1994-01-04 1997-07-03 Asta Medica Ag Verpackung für kleine vordosierte Mengen eines fein verteilten Feststoffs
US5642727A (en) * 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
FR2738152B1 (fr) * 1995-09-04 1998-01-23 Tebro Dispositif de pre-dosage de produit pulverulent pour un distributeur de produit
DE19733651A1 (de) 1997-08-04 1999-02-18 Boehringer Ingelheim Pharma Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole
WO2001041846A1 (en) * 1999-12-11 2001-06-14 Glaxo Group Limited Medicament dispenser
US6443307B1 (en) * 2000-01-25 2002-09-03 Michael D. Burridge Medication dispenser with an internal ejector
US20030034271A1 (en) * 2000-01-25 2003-02-20 Burridge Michael D. Internal ejector punch for blister-pack type containers
TWI224515B (en) * 2000-06-23 2004-12-01 Norton Healthcare Ltd Pre-metered dose magazine for breath-actuated dry powder inhaler
US6443367B1 (en) * 2000-09-11 2002-09-03 Joseph Bova Deepwatering device
GB0120018D0 (en) * 2001-08-16 2001-10-10 Meridica Ltd Pack containing medicament and dispensing device
GB0303870D0 (en) * 2003-02-20 2003-03-26 Norton Healthcare Ltd Pre-metered dose magazine for breath-actuated dry powder inhaler
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device

Also Published As

Publication number Publication date
WO2007118342A3 (de) 2008-01-17
EP2004262B1 (de) 2019-08-14
EP1844809A1 (de) 2007-10-17
US20090250057A1 (en) 2009-10-08
JP2009533097A (ja) 2009-09-17
US8267082B2 (en) 2012-09-18
EP2004262A2 (de) 2008-12-24
CA2644013A1 (en) 2007-10-25
WO2007118342A2 (de) 2007-10-25

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