CA2623769C - Composition and method for the prevention of oral disease - Google Patents

Composition and method for the prevention of oral disease Download PDF

Info

Publication number
CA2623769C
CA2623769C CA2623769A CA2623769A CA2623769C CA 2623769 C CA2623769 C CA 2623769C CA 2623769 A CA2623769 A CA 2623769A CA 2623769 A CA2623769 A CA 2623769A CA 2623769 C CA2623769 C CA 2623769C
Authority
CA
Canada
Prior art keywords
gram
bacteria
oral
chlorine dioxide
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2623769A
Other languages
English (en)
French (fr)
Other versions
CA2623769A1 (en
Inventor
James L. Ratcliff
David R. Drake
Sally A. Cunningham
Elizabeth A. Renken
Elena J. Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micropure Inc
Original Assignee
Micropure Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micropure Inc filed Critical Micropure Inc
Publication of CA2623769A1 publication Critical patent/CA2623769A1/en
Application granted granted Critical
Publication of CA2623769C publication Critical patent/CA2623769C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2623769A 2007-07-09 2008-02-29 Composition and method for the prevention of oral disease Active CA2623769C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/774,730 US20090016973A1 (en) 2007-07-09 2007-07-09 Composition and Method for the Prevention of Oral Disease
US11/774,730 2007-07-09

Publications (2)

Publication Number Publication Date
CA2623769A1 CA2623769A1 (en) 2009-01-09
CA2623769C true CA2623769C (en) 2019-02-12

Family

ID=40224433

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2623769A Active CA2623769C (en) 2007-07-09 2008-02-29 Composition and method for the prevention of oral disease

Country Status (7)

Country Link
US (1) US20090016973A1 (es)
EP (2) EP2200441B1 (es)
JP (2) JP5714900B2 (es)
CA (1) CA2623769C (es)
ES (2) ES2543132T3 (es)
HK (2) HK1143929A1 (es)
WO (1) WO2009009163A1 (es)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7383423B1 (en) * 2004-10-01 2008-06-03 Advanced Micro Devices, Inc. Shared resources in a chip multiprocessor
US8926951B2 (en) * 2007-07-09 2015-01-06 Micropure, Inc. Composition for preventing oral disease by penetrating polymicrobial oral biofilms and killing oral pathogens
WO2010036427A1 (en) 2008-06-17 2010-04-01 Brigham Young University Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods
US20100009009A1 (en) 2008-07-10 2010-01-14 Micropure, Inc. Method and composition for prevention and treatment of oral fungal infections
WO2010009063A2 (en) 2008-07-15 2010-01-21 Basf Corporation Non-cytotoxic chlorine dioxide fluids
CL2009001581A1 (es) * 2008-07-15 2010-09-10 Basf Corp Metodo para pulir una superficie dental, donde se pone en contacto dicha superficie con una composicion de pulido sustancialmente no irritante y comprende dioxido de cloro;
US20100062042A1 (en) * 2008-07-15 2010-03-11 Basf Catalysts Llc Methods, Systems and Devices for Administration of Chlorine Dioxide
US8311625B2 (en) 2009-02-04 2012-11-13 Basf Corporation Chlorine dioxide treatment for biological tissue
US20100233101A1 (en) * 2009-02-13 2010-09-16 Micropure, Inc. Composition and method for the oxidative consumption of salivary biomolecules
EP2429308A4 (en) * 2009-05-01 2012-11-14 Basf Corp GUM AND SUGAR BASED ON CHLORINE DIOXIDE
US8992831B2 (en) 2009-09-25 2015-03-31 E. I. Du Pont De Nemours And Company Stabilized chlorine dioxide to preserve carbohydrate feedstocks
WO2011094657A2 (en) 2010-01-31 2011-08-04 Basf Corporation Additives for chlorine dioxide-containing compositions
ES2725784T3 (es) 2011-07-20 2019-09-27 Univ Brigham Young Compuestos de ceragenina hidrófobos y dispositivos que incorporan al mismo
US9694019B2 (en) 2011-09-13 2017-07-04 Brigham Young University Compositions and methods for treating bone diseases and broken bones
JP6038154B2 (ja) 2011-09-13 2016-12-07 ブリガム・ヤング・ユニバーシティＢｒｉｇｈａｍ Ｙｏｕｎｇ Ｕｎｉｖｅｒｓｉｔｙ 骨疾患および破断骨治療のための組成物
US9603859B2 (en) 2011-09-13 2017-03-28 Brigham Young University Methods and products for increasing the rate of healing of tissue wounds
WO2013040269A1 (en) 2011-09-13 2013-03-21 Brigham Young University Products for healing of tissue wounds
AU2011385377B2 (en) 2011-12-21 2017-06-01 Brigham Young University Oral care compositions
US20140363780A1 (en) * 2011-12-21 2014-12-11 Brigham Young University Oral care compositions
GB201202341D0 (en) 2012-02-10 2012-03-28 Periproducts Ltd Multicomponent oral care compostion
US9533063B1 (en) 2012-03-01 2017-01-03 Brigham Young University Aerosols incorporating ceragenin compounds and methods of use thereof
EP3225113B1 (en) 2012-05-02 2020-09-02 Brigham Young University Methods for making ceragenin particulate materials
WO2014033625A2 (en) * 2012-08-27 2014-03-06 University Of Pretoria Oral care
EP2908826A1 (en) 2012-10-17 2015-08-26 Brigham Young University Treatment and prevention of mastitis
KR102203375B1 (ko) 2013-01-07 2021-01-15 브라이엄 영 유니버시티 세포 증식을 감소시키는 방법 및 소정의 질환을 치료하는 방법
CN110420211A (zh) 2013-03-15 2019-11-08 布莱阿姆青年大学 治疗炎症、自身免疫性疾病和疼痛的方法
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US10568893B2 (en) 2013-03-15 2020-02-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US9387215B2 (en) 2013-04-22 2016-07-12 Brigham Young University Animal feed including cationic cholesterol additive and related methods
US10471109B2 (en) 2013-05-04 2019-11-12 The Board Of Regents Of The University Of Texas System Compositions and methods for promoting nitric oxide production through an oral delivery system
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
CA2844321C (en) 2014-02-27 2021-03-16 Brigham Young University Cationic steroidal antimicrobial compounds
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US9867836B2 (en) 2014-03-13 2018-01-16 Brigham Young University Lavage and/or infusion using CSA compounds for increasing fertility in a mammal
US9931350B2 (en) 2014-03-14 2018-04-03 Brigham Young University Anti-infective and osteogenic compositions and methods of use
US9686966B2 (en) 2014-04-30 2017-06-27 Brigham Young University Methods and apparatus for cleaning or disinfecting a water delivery system
US10238665B2 (en) 2014-06-26 2019-03-26 Brigham Young University Methods for treating fungal infections
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
US10227376B2 (en) 2014-08-22 2019-03-12 Brigham Young University Radiolabeled cationic steroid antimicrobials and diagnostic methods
US10155788B2 (en) 2014-10-07 2018-12-18 Brigham Young University Cationic steroidal antimicrobial prodrug compositions and uses thereof
WO2016172553A1 (en) 2015-04-22 2016-10-27 Savage Paul B Methods for the synthesis of ceragenins
WO2016172543A1 (en) 2015-04-22 2016-10-27 Savage Paul B Methods for the synthesis of ceragenins
US9434759B1 (en) 2015-05-18 2016-09-06 Brigham Young University Cationic steroidal antimicrobial compounds and methods of manufacturing such compounds
US20170157013A1 (en) * 2015-12-07 2017-06-08 Colgate-Palmolive Company Metal Amino Acid Complexes for Bacterial Aggregation
US10226550B2 (en) 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
JPWO2018012011A1 (ja) * 2016-07-11 2018-07-19 三菱ケミカル株式会社 口腔内検査方法
US10959433B2 (en) 2017-03-21 2021-03-30 Brigham Young University Use of cationic steroidal antimicrobials for sporicidal activity
CA3020197C (en) 2017-09-01 2024-06-04 Micropure, Inc. Aliphatic anionic compounds and oxidative compounds with improved stability and efficacy for use in pharmaceutical compositions

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3271242A (en) * 1963-03-29 1966-09-06 Alexander R Reed Iii Stable chlorine dioxide composition and method of making same
JPS6054311A (ja) * 1983-09-04 1985-03-28 Mitsuru Tsuchikura 口臭に係る消臭殺菌溶液。
US4855135A (en) * 1984-07-30 1989-08-08 Ratcliff Perry A Method for debriding
US4818519A (en) * 1986-12-29 1989-04-04 Ratcliff Perry A Method and composition for prevention of plaque formation and plaque dependent diseases
US4975285A (en) * 1984-07-30 1990-12-04 Ratcliff Perry A Method for cleaning dental prosthetic devices
US4793989A (en) * 1984-07-30 1988-12-27 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4689215A (en) * 1984-07-30 1987-08-25 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4889714A (en) * 1984-07-30 1989-12-26 Ratcliff Perry A Method for retarding dental plaque by killing streptococcus sanguis
US4696811A (en) * 1984-07-30 1987-09-29 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4886657A (en) * 1984-07-30 1989-12-12 Ratcliff Perry A Method for preventing periodontitis
US4788053A (en) * 1984-07-30 1988-11-29 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4837009A (en) * 1986-03-31 1989-06-06 Ratcliff Perry A Method and composition for prevention of plaque formation and plaque dependent diseases
US4792442A (en) * 1986-03-31 1988-12-20 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4925656A (en) * 1986-03-31 1990-05-15 Ratcliff Perry A Method for retarding formation of dental plaque
US4786492A (en) * 1986-03-31 1988-11-22 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4851213A (en) * 1986-03-31 1989-07-25 Ratcliff Perry A Method and composition for prevention and treatment of oral disease due to S. Sanguis
US4808389A (en) * 1986-12-29 1989-02-28 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US5348734A (en) * 1990-11-20 1994-09-20 Micropure Inc. Oral health preparation and method
EP0613678B1 (en) * 1986-12-29 1997-11-19 Micropure, Inc. Oral care composition
US5200171A (en) * 1990-11-20 1993-04-06 Micropure, Inc. Oral health preparation and method
US5284648A (en) * 1989-03-17 1994-02-08 White Robert D Alcohol-free, oral rinse and pre-rinse emulsions method of prepration and method of use
US5281412A (en) * 1991-12-30 1994-01-25 The Procter & Gamble Company Oral compositions
US6200557B1 (en) * 1993-07-06 2001-03-13 Perry A. Ratcliff Method of treating HIV by a topical composition
US5489435A (en) * 1993-07-06 1996-02-06 Ratcliff; Perry A. Composition for treatment of abnormal conditions of the epithelium of bodily orifices
AU2204995A (en) * 1994-04-07 1995-10-30 Jon L. Richter Oral rinse and method of treating halitosis
US6350438B1 (en) * 1998-02-27 2002-02-26 The Procter & Gamble Company Oral care compositions comprising chlorite and methods
US6132702A (en) * 1998-02-27 2000-10-17 The Procter & Gamble Company Oral care compositions comprising chlorite and methods
US6846478B1 (en) * 1998-02-27 2005-01-25 The Procter & Gamble Company Promoting whole body health
US6391577B1 (en) * 1999-03-03 2002-05-21 Susan R. Mikkelsen Rapid electrochemical assay for antibiotic and cytotoxic drug susceptibility in microorganisms
US6231830B1 (en) * 1999-03-04 2001-05-15 George Madray Method of making molecular chlorine dioxide
US7087228B2 (en) * 2002-07-03 2006-08-08 University Of Southern California Preventing tooth decay and infective endocarditis using natural oligopeptides

Also Published As

Publication number Publication date
EP2200441A4 (en) 2011-01-05
HK1212598A1 (zh) 2016-06-17
JP2014040470A (ja) 2014-03-06
EP2921174B1 (en) 2018-05-16
JP6087781B2 (ja) 2017-03-01
JP5714900B2 (ja) 2015-05-07
EP2200441A1 (en) 2010-06-30
ES2543132T3 (es) 2015-08-14
WO2009009163A1 (en) 2009-01-15
EP2921174A1 (en) 2015-09-23
ES2682457T3 (es) 2018-09-20
JP2010533189A (ja) 2010-10-21
EP2200441B1 (en) 2014-12-10
HK1143929A1 (en) 2011-01-21
US20090016973A1 (en) 2009-01-15
CA2623769A1 (en) 2009-01-09

Similar Documents

Publication Publication Date Title
CA2623769C (en) Composition and method for the prevention of oral disease
Koo et al. Effects of apigenin and tt‐farnesol on glucosyltransferase activity, biofilm viability and caries development in rats
Johansson et al. Antibacterial effect of ozone on cariogenic bacterial species
Spahr et al. Effect of the enamel matrix derivative Emdogain® on the growth of periodontal pathogens in vitro
Allaker et al. Novel anti-microbial therapies for dental plaque-related diseases
AU2015202853B2 (en) Composition and method for preventing oral disease
JPS6234731B2 (es)
JP2004300157A (ja) 感染治療および叢制御の方法および組成物
Wuersching et al. Targeting antibiotic tolerance in anaerobic biofilms associated with oral diseases: Human antimicrobial peptides LL-37 and lactoferricin enhance the antibiotic efficacy of amoxicillin, clindamycin and metronidazole
Chamlagain et al. Anti-bacterial and anti-biofilm activities of arachidonic acid against the cariogenic bacterium Streptococcus mutans
WO2021096388A1 (ru) Композиция с пролонгированным эффектом антибактериального действия
Meurman et al. Oral infection and vascular disease
Ghazali et al. Level of Salivary Microorganisms After Consumption of Malaysian Tualang Honey: A Preliminary Study
EP4230212A1 (en) Composition and kits for the prevention or treatment of gum diseases
US20220331224A1 (en) Enzymatic targeting cariogenic bacterial-fungal biofilm interaction
Amornvit et al. In vitro Efficacy of Newly Formulated Oil Pulling against Oral Malodor Related Microbiota
Yuslianti et al. The Effect of Rambutan Honey Toothpaste On The Diameter Of The Inhibition Zone For The Growht Of Staphylococcus aureus
Amtha et al. A Comparison of Commercial Mouthwashes Towards Oral Pathogens Biofilms in vitro
Камилов et al. ETIOPATHOGENETIC CHARACTERISTICS OF CHRONIC CATARRHAL GINGIVITIS
Saha A new probiotic approach for the prevention and/or treatment of dental caries, oral candidiasis and periodontal diseases
Bensreti Investigating the Antibacterial and Antibiofilm Potential of Honey on Plaque Bacteria
Dąbrowska et al. Effect of chlorhexidine mouthrinse on cathepsin C activity in human saliva
GAETTI-JARDIM Influence of subinhibitory concentrations of extracts from Psidium cattleianum (Sabine) and Myracrodruon urundeuva (Allemao) on mutans streptococci adhesion to glass and enamel surfaces

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20130204