CA2616712C - Systeme marqueur cellulaire/ligand, ou le marqueur est du type eph, materiau cellulaire comprenant ce systeme, procede de preparation et utilisation proangiogenique - Google Patents
Systeme marqueur cellulaire/ligand, ou le marqueur est du type eph, materiau cellulaire comprenant ce systeme, procede de preparation et utilisation proangiogenique Download PDFInfo
- Publication number
- CA2616712C CA2616712C CA2616712A CA2616712A CA2616712C CA 2616712 C CA2616712 C CA 2616712C CA 2616712 A CA2616712 A CA 2616712A CA 2616712 A CA2616712 A CA 2616712A CA 2616712 C CA2616712 C CA 2616712C
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- Prior art keywords
- cell
- ephrin
- marker
- ephb
- ligand
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
- C12N5/0692—Stem cells; Progenitor cells; Precursor cells
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- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0508029 | 2005-07-27 | ||
| FR0508029A FR2889200B1 (fr) | 2005-07-27 | 2005-07-27 | Systeme marqueur cellulaire/ligand, ou le marqueur est du type eph, materiau cellulaire comprenant ce systeme, procede de preparation et utilisation proangiogenique |
| PCT/FR2006/001837 WO2007012764A2 (fr) | 2005-07-27 | 2006-07-27 | Système marqueur cellulaire/ligand, où le marqueur est du type eph, matériau cellulaire comprenant ce système, procédé de préparation et utilisation proangiogénique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2616712A1 CA2616712A1 (fr) | 2007-02-01 |
| CA2616712C true CA2616712C (fr) | 2015-11-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2616712A Expired - Fee Related CA2616712C (fr) | 2005-07-27 | 2006-07-27 | Systeme marqueur cellulaire/ligand, ou le marqueur est du type eph, materiau cellulaire comprenant ce systeme, procede de preparation et utilisation proangiogenique |
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| Country | Link |
|---|---|
| US (1) | US8338169B2 (enExample) |
| EP (1) | EP1913130B1 (enExample) |
| JP (4) | JP5755829B2 (enExample) |
| CN (1) | CN101273123B (enExample) |
| AU (1) | AU2006273928B2 (enExample) |
| CA (1) | CA2616712C (enExample) |
| DK (1) | DK1913130T3 (enExample) |
| ES (1) | ES2565675T3 (enExample) |
| FR (1) | FR2889200B1 (enExample) |
| IL (1) | IL188938A (enExample) |
| WO (1) | WO2007012764A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2909559B1 (fr) * | 2006-12-06 | 2012-09-07 | Inst Vaisseaux Et Du Sang | Preparations cellulaires pour une utilisation comme agent stimulant la revascularisation |
| AU2008223817A1 (en) | 2007-03-02 | 2008-09-12 | National University Of Ireland, Galway | Osteopontin for the prediction and treatment of cardiovascular diseases |
| FR2957799B1 (fr) * | 2010-03-26 | 2012-08-17 | Inst Des Vaisseaux Et Du Sang | Compositions proangiogeniques, leur procede de preparation et leurs utilisations |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE4240635C2 (de) * | 1992-12-03 | 1997-07-10 | Lothar Prof Dr Kanz | Vermehrung hämatopoetischer Vorläuferzellen ex vivo sowieZusammensetzungen hämatopoetischer Wachstumsfaktoren |
| US5980887A (en) * | 1996-11-08 | 1999-11-09 | St. Elizabeth's Medical Center Of Boston | Methods for enhancing angiogenesis with endothelial progenitor cells |
| US6864227B1 (en) | 1998-04-13 | 2005-03-08 | California Institute Of Technology | Artery-and vein-specific proteins and uses therefor |
| WO2000031124A2 (en) | 1998-11-20 | 2000-06-02 | Mount Sinai Hospital | Peptides that modulate the interaction of b class ephrins and pdz domains |
| US6610534B2 (en) | 2000-10-05 | 2003-08-26 | Novartis Ag | Induction of blood vessel formation through administration of polynucleotides encoding sphingosine kinases |
| AU2002243623A1 (en) | 2001-01-26 | 2002-08-06 | Regeneron Pharmaceuticals, Inc. | Methods of imaging and targeting vasculature |
| AU2002311792A1 (en) | 2001-03-30 | 2002-10-15 | President And Fellows Of Harvard College | B-ephrin regulation of g-protein coupled chemoattraction; compositions and methods of use |
| US20050049194A1 (en) | 2001-11-09 | 2005-03-03 | Jonas Frisen | Use of ephrins and related molecules to regulate cellular proliferation |
| AU2003232457A1 (en) | 2002-05-29 | 2003-12-19 | Curagen Corporation | Compositions and methods of use for an ephrin rreceptor |
| US20040110150A1 (en) | 2002-12-10 | 2004-06-10 | Isis Pharmaceuticals Inc. | Modulation of Ephrin-B2 expression |
| US7576074B2 (en) | 2002-07-15 | 2009-08-18 | Rice Kenneth D | Receptor-type kinase modulators and methods of use |
| AU2003900541A0 (en) | 2003-02-07 | 2003-02-20 | Ludwig Institute For Cancer Research | Modulation of cell adhesion and tumour cell metastasis |
| AU2004220459B2 (en) | 2003-03-12 | 2010-08-05 | Vasgene Therapeutics, Inc. | Polypeptide compounds for inhibiting angiogenesis and tumor growth |
-
2005
- 2005-07-27 FR FR0508029A patent/FR2889200B1/fr not_active Expired - Lifetime
-
2006
- 2006-07-27 US US11/996,862 patent/US8338169B2/en not_active Expired - Fee Related
- 2006-07-27 EP EP06794234.2A patent/EP1913130B1/fr active Active
- 2006-07-27 CA CA2616712A patent/CA2616712C/fr not_active Expired - Fee Related
- 2006-07-27 AU AU2006273928A patent/AU2006273928B2/en not_active Ceased
- 2006-07-27 CN CN2006800358867A patent/CN101273123B/zh not_active Expired - Fee Related
- 2006-07-27 JP JP2008523415A patent/JP5755829B2/ja not_active Expired - Fee Related
- 2006-07-27 DK DK06794234.2T patent/DK1913130T3/en active
- 2006-07-27 ES ES06794234.2T patent/ES2565675T3/es active Active
- 2006-07-27 WO PCT/FR2006/001837 patent/WO2007012764A2/fr not_active Ceased
-
2008
- 2008-01-22 IL IL188938A patent/IL188938A/en active IP Right Grant
-
2014
- 2014-12-17 JP JP2014255610A patent/JP5981525B2/ja not_active Expired - Fee Related
-
2016
- 2016-03-15 JP JP2016050940A patent/JP6235639B2/ja not_active Expired - Fee Related
-
2017
- 2017-06-21 JP JP2017121385A patent/JP2017169590A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007012764A2 (fr) | 2007-02-01 |
| JP6235639B2 (ja) | 2017-11-22 |
| ES2565675T3 (es) | 2016-04-06 |
| CN101273123B (zh) | 2013-06-26 |
| CN101273123A (zh) | 2008-09-24 |
| IL188938A0 (en) | 2008-04-13 |
| EP1913130B1 (fr) | 2015-12-23 |
| JP2017169590A (ja) | 2017-09-28 |
| JP5755829B2 (ja) | 2015-07-29 |
| AU2006273928B2 (en) | 2012-02-16 |
| IL188938A (en) | 2014-09-30 |
| AU2006273928A1 (en) | 2007-02-01 |
| JP2009505638A (ja) | 2009-02-12 |
| DK1913130T3 (en) | 2016-03-29 |
| US8338169B2 (en) | 2012-12-25 |
| FR2889200B1 (fr) | 2008-01-04 |
| JP5981525B2 (ja) | 2016-08-31 |
| FR2889200A1 (fr) | 2007-02-02 |
| EP1913130A2 (fr) | 2008-04-23 |
| CA2616712A1 (fr) | 2007-02-01 |
| JP2016127863A (ja) | 2016-07-14 |
| WO2007012764A3 (fr) | 2007-05-31 |
| US20090123431A1 (en) | 2009-05-14 |
| JP2015061536A (ja) | 2015-04-02 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20210727 |