CA2615427A1 - Contraception orale a l'aide de trimegestone - Google Patents
Contraception orale a l'aide de trimegestone Download PDFInfo
- Publication number
- CA2615427A1 CA2615427A1 CA002615427A CA2615427A CA2615427A1 CA 2615427 A1 CA2615427 A1 CA 2615427A1 CA 002615427 A CA002615427 A CA 002615427A CA 2615427 A CA2615427 A CA 2615427A CA 2615427 A1 CA2615427 A1 CA 2615427A1
- Authority
- CA
- Canada
- Prior art keywords
- ethinyloestradiol
- trimegestone
- dose
- combination
- days
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229950008546 trimegestone Drugs 0.000 title claims abstract description 137
- JUNDJWOLDSCTFK-MTZCLOFQSA-N trimegestone Chemical compound C1CC2=CC(=O)CCC2=C2[C@@H]1[C@@H]1CC[C@@](C(=O)[C@@H](O)C)(C)[C@@]1(C)CC2 JUNDJWOLDSCTFK-MTZCLOFQSA-N 0.000 title claims abstract description 136
- 229960002568 ethinylestradiol Drugs 0.000 claims abstract description 124
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 claims abstract description 123
- 230000027758 ovulation cycle Effects 0.000 claims abstract description 33
- 238000000034 method Methods 0.000 claims abstract description 32
- 239000000262 estrogen Substances 0.000 claims description 65
- 239000002552 dosage form Substances 0.000 claims description 54
- 238000002360 preparation method Methods 0.000 claims description 45
- 239000000203 mixture Substances 0.000 claims description 43
- 229930182833 estradiol Natural products 0.000 claims description 26
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims description 24
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 24
- 239000008194 pharmaceutical composition Substances 0.000 claims description 23
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- MPJKWIXIYCLVCU-UHFFFAOYSA-N Folinic acid Natural products NC1=NC2=C(N(C=O)C(CNc3ccc(cc3)C(=O)NC(CCC(=O)O)CC(=O)O)CN2)C(=O)N1 MPJKWIXIYCLVCU-UHFFFAOYSA-N 0.000 claims description 9
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- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 description 8
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- PLSARIKBYIPYPF-UHFFFAOYSA-H trimagnesium dicitrate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O PLSARIKBYIPYPF-UHFFFAOYSA-H 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005034498.4 | 2005-07-20 | ||
DE102005034498A DE102005034498A1 (de) | 2005-07-20 | 2005-07-20 | Orale Kontrazeption mit Trimegeston |
US11/348,545 US20070021396A1 (en) | 2005-07-20 | 2006-02-06 | Oral contraception with trimegestone |
US11/348,545 | 2006-02-06 | ||
PCT/EP2006/007103 WO2007009769A1 (fr) | 2005-07-20 | 2006-07-19 | Contraception orale a l'aide de trimegestone |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2615427A1 true CA2615427A1 (fr) | 2007-01-25 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002615427A Abandoned CA2615427A1 (fr) | 2005-07-20 | 2006-07-19 | Contraception orale a l'aide de trimegestone |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1909799A1 (fr) |
KR (1) | KR20080031435A (fr) |
AR (1) | AR056674A1 (fr) |
AU (1) | AU2006271920A1 (fr) |
CA (1) | CA2615427A1 (fr) |
WO (1) | WO2007009769A1 (fr) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998004246A2 (fr) * | 1996-07-26 | 1998-02-05 | American Home Prod | Contraceptif oral |
FR2801218B1 (fr) * | 1999-11-23 | 2001-12-28 | Hoechst Marion Roussel Inc | Compositions pharmaceutiques comprenant de la trimegestone, leurs procedes de preparation ainsi que le conditionnement primaire les renfermant |
-
2006
- 2006-07-19 WO PCT/EP2006/007103 patent/WO2007009769A1/fr active Application Filing
- 2006-07-19 EP EP06762699A patent/EP1909799A1/fr not_active Withdrawn
- 2006-07-19 AU AU2006271920A patent/AU2006271920A1/en not_active Abandoned
- 2006-07-19 CA CA002615427A patent/CA2615427A1/fr not_active Abandoned
- 2006-07-19 AR ARP060103101A patent/AR056674A1/es unknown
- 2006-07-19 KR KR1020087004095A patent/KR20080031435A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2006271920A1 (en) | 2007-01-25 |
WO2007009769A1 (fr) | 2007-01-25 |
AR056674A1 (es) | 2007-10-17 |
EP1909799A1 (fr) | 2008-04-16 |
KR20080031435A (ko) | 2008-04-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |
Effective date: 20130719 |