CA2611938A1

CA2611938A1 - Modified release ticlopidine compositions

Modified release ticlopidine compositions Download PDF

Info

Publication number: CA2611938A1
Authority: CA; Canada
Prior art keywords: composition; component; ticlopidine; release; active ingredient
Prior art date: 2005-06-13
Legal status : Abandoned

Application number

CA002611938A

Other languages

English (en)

French (fr)

Inventor

Gary Liversidge

Scott Jenkins

Paul Stark

Niall Fanning

Gurvinder Rekhi

John Devane

Bruce J. Christensen

Current Assignee

Elan Pharma International Ltd

Original Assignee

Individual

Priority date

2005-06-13

Filing date

2006-06-09

Publication date

2007-01-25

2006-03-10 Priority claimed from US11/372,857 external-priority patent/US20060240105A1/en

2006-06-09 Application filed by Individual filed Critical Individual

2007-01-25 Publication of CA2611938A1 publication Critical patent/CA2611938A1/en

Status Abandoned legal-status Critical Current

Links

239000000203 mixture Substances 0.000 title claims abstract description 147
PHWBOXQYWZNQIN-UHFFFAOYSA-N ticlopidine Chemical compound ClC1=CC=CC=C1CN1CC(C=CS2)=C2CC1 PHWBOXQYWZNQIN-UHFFFAOYSA-N 0.000 title claims abstract description 94
239000005528 B01AC05 - Ticlopidine Substances 0.000 title claims abstract description 90
229960005001 ticlopidine Drugs 0.000 title claims abstract description 90
239000004480 active ingredient Substances 0.000 claims abstract description 88
239000002245 particle Substances 0.000 claims abstract description 52
230000002902 bimodal effect Effects 0.000 claims abstract description 17
238000000034 method Methods 0.000 claims abstract description 17
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239000002552 dosage form Substances 0.000 claims description 51
239000012729 immediate-release (IR) formulation Substances 0.000 claims description 45
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MTKNGOHFNXIVOS-UHFFFAOYSA-N ticlopidine hydrochloride Chemical compound [H+].[Cl-].ClC1=CC=CC=C1CN1CC(C=CS2)=C2CC1 MTKNGOHFNXIVOS-UHFFFAOYSA-N 0.000 description 13
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