CA2610866C - Compositions for treating sleep-related breathing disorders comprising cholecystokinin (cck) receptor antagonists - Google Patents

Compositions for treating sleep-related breathing disorders comprising cholecystokinin (cck) receptor antagonists Download PDF

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Publication number
CA2610866C
CA2610866C CA2610866A CA2610866A CA2610866C CA 2610866 C CA2610866 C CA 2610866C CA 2610866 A CA2610866 A CA 2610866A CA 2610866 A CA2610866 A CA 2610866A CA 2610866 C CA2610866 C CA 2610866C
Authority
CA
Canada
Prior art keywords
cck
receptor antagonist
sleep
receptor
antagonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2610866A
Other languages
English (en)
French (fr)
Other versions
CA2610866A1 (en
Inventor
David W. Carley
Miodrag Radulovacki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Illinois System
Original Assignee
University of Illinois System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Illinois System filed Critical University of Illinois System
Publication of CA2610866A1 publication Critical patent/CA2610866A1/en
Application granted granted Critical
Publication of CA2610866C publication Critical patent/CA2610866C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2207Gastrins; Cholecystokinins [CCK]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2610866A 2005-06-06 2006-06-06 Compositions for treating sleep-related breathing disorders comprising cholecystokinin (cck) receptor antagonists Expired - Fee Related CA2610866C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68780305P 2005-06-06 2005-06-06
US60/687,803 2005-06-06
PCT/US2006/021929 WO2006133197A1 (en) 2005-06-06 2006-06-06 Compositions and methods for treating sleep disorders

Publications (2)

Publication Number Publication Date
CA2610866A1 CA2610866A1 (en) 2006-12-14
CA2610866C true CA2610866C (en) 2015-07-28

Family

ID=37498776

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2610866A Expired - Fee Related CA2610866C (en) 2005-06-06 2006-06-06 Compositions for treating sleep-related breathing disorders comprising cholecystokinin (cck) receptor antagonists

Country Status (7)

Country Link
US (3) US8053413B2 (enExample)
EP (1) EP1898921B1 (enExample)
JP (1) JP5197361B2 (enExample)
AU (1) AU2006255047B2 (enExample)
CA (1) CA2610866C (enExample)
ES (1) ES2423412T3 (enExample)
WO (1) WO2006133197A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8053413B2 (en) * 2005-06-06 2011-11-08 The Board Of Trustees Of The University Of Illinois Methods for treating sleep disorders by cholecystokinin (CCK) receptor B antagonists
WO2007047575A2 (en) * 2005-10-14 2007-04-26 The Board Of Trustees Of The University Of Illinois Pharmacological treatments for sleep-related breathing disorders
EP2142183A2 (en) * 2007-04-09 2010-01-13 Sepracor Inc. Methods and compositions comprising desvenlafaxine or duloxetine for treating sleep-related breathing disorders
WO2015077572A1 (en) 2013-11-22 2015-05-28 CL BioSciences LLC Gastrin antagonists (eg yf476, netazepide) for treatment and prevention of osteoporosis
CN106413541B (zh) * 2014-01-08 2021-04-06 纽罗荣动力学公司 用于诊断睡眠的系统和方法
EP3537961B1 (en) 2016-11-10 2025-06-25 The Research Foundation for The State University of New York System, method and biomarkers for airway obstruction
US20250009720A1 (en) * 2021-11-11 2025-01-09 Apnimed, Inc. (Delaware) Methods and compositions for treating sleep apnea

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820834A (en) 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
IL104853A (en) 1992-02-27 1997-11-20 Yamanouchi Pharma Co Ltd Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them
JP2862675B2 (ja) 1993-07-26 1999-03-03 フアイザー・インコーポレイテツド 選択的コレシストキニン−b受容体拮抗薬としてのテトラヒドロ−1h−ベンゾアゼピノンおよびヘキサヒドロアゼピノン
GB2282595A (en) 1993-08-25 1995-04-12 Yamanouchi Pharma Co Ltd Benzodiazepine derivatives
IT1286141B1 (it) 1996-07-02 1998-07-07 Rotta Research Lab Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico.
US20040198723A1 (en) * 2002-01-22 2004-10-07 Karen Gibson Method of treatment
US8053413B2 (en) * 2005-06-06 2011-11-08 The Board Of Trustees Of The University Of Illinois Methods for treating sleep disorders by cholecystokinin (CCK) receptor B antagonists

Also Published As

Publication number Publication date
US20080200367A1 (en) 2008-08-21
AU2006255047B2 (en) 2011-09-15
US20120010198A1 (en) 2012-01-12
EP1898921A4 (en) 2008-11-05
EP1898921A1 (en) 2008-03-19
AU2006255047A1 (en) 2006-12-14
EP1898921B1 (en) 2013-05-01
WO2006133197A9 (en) 2007-03-22
JP2008542443A (ja) 2008-11-27
ES2423412T3 (es) 2013-09-20
CA2610866A1 (en) 2006-12-14
US20140045755A1 (en) 2014-02-13
WO2006133197A1 (en) 2006-12-14
JP5197361B2 (ja) 2013-05-15
US8053413B2 (en) 2011-11-08

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MKLA Lapsed

Effective date: 20170606