AU2006255047B2 - Compositions and methods for treating sleep disorders - Google Patents
Compositions and methods for treating sleep disorders Download PDFInfo
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- AU2006255047B2 AU2006255047B2 AU2006255047A AU2006255047A AU2006255047B2 AU 2006255047 B2 AU2006255047 B2 AU 2006255047B2 AU 2006255047 A AU2006255047 A AU 2006255047A AU 2006255047 A AU2006255047 A AU 2006255047A AU 2006255047 B2 AU2006255047 B2 AU 2006255047B2
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- cck
- sleep
- apnea
- receptor
- agents
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 239000003029 tricyclic antidepressant agent Substances 0.000 description 1
- 210000003901 trigeminal nerve Anatomy 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 229960004747 ubidecarenone Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 230000003519 ventilatory effect Effects 0.000 description 1
- 230000002861 ventricular Effects 0.000 description 1
- 206010047302 ventricular tachycardia Diseases 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- BPICBUSOMSTKRF-UHFFFAOYSA-N xylazine Chemical compound CC1=CC=CC(C)=C1NC1=NCCCS1 BPICBUSOMSTKRF-UHFFFAOYSA-N 0.000 description 1
- 229960001600 xylazine Drugs 0.000 description 1
- 229950004681 zacopride Drugs 0.000 description 1
- 229960002791 zimeldine Drugs 0.000 description 1
- OYPPVKRFBIWMSX-SXGWCWSVSA-N zimeldine Chemical compound C=1C=CN=CC=1C(=C/CN(C)C)\C1=CC=C(Br)C=C1 OYPPVKRFBIWMSX-SXGWCWSVSA-N 0.000 description 1
- 229960001360 zolmitriptan Drugs 0.000 description 1
- UTAZCRNOSWWEFR-ZDUSSCGKSA-N zolmitriptan Chemical compound C=1[C]2C(CCN(C)C)=CN=C2C=CC=1C[C@H]1COC(=O)N1 UTAZCRNOSWWEFR-ZDUSSCGKSA-N 0.000 description 1
- ZAFYATHCZYHLPB-UHFFFAOYSA-N zolpidem Chemical compound N1=C2C=CC(C)=CN2C(CC(=O)N(C)C)=C1C1=CC=C(C)C=C1 ZAFYATHCZYHLPB-UHFFFAOYSA-N 0.000 description 1
- 229960001475 zolpidem Drugs 0.000 description 1
- 229960002911 zonisamide Drugs 0.000 description 1
- UBQNRHZMVUUOMG-UHFFFAOYSA-N zonisamide Chemical compound C1=CC=C2C(CS(=O)(=O)N)=NOC2=C1 UBQNRHZMVUUOMG-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2207—Gastrins; Cholecystokinins [CCK]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68780305P | 2005-06-06 | 2005-06-06 | |
| US60/687,803 | 2005-06-06 | ||
| PCT/US2006/021929 WO2006133197A1 (en) | 2005-06-06 | 2006-06-06 | Compositions and methods for treating sleep disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2006255047A1 AU2006255047A1 (en) | 2006-12-14 |
| AU2006255047B2 true AU2006255047B2 (en) | 2011-09-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2006255047A Ceased AU2006255047B2 (en) | 2005-06-06 | 2006-06-06 | Compositions and methods for treating sleep disorders |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US8053413B2 (enExample) |
| EP (1) | EP1898921B1 (enExample) |
| JP (1) | JP5197361B2 (enExample) |
| AU (1) | AU2006255047B2 (enExample) |
| CA (1) | CA2610866C (enExample) |
| ES (1) | ES2423412T3 (enExample) |
| WO (1) | WO2006133197A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8053413B2 (en) * | 2005-06-06 | 2011-11-08 | The Board Of Trustees Of The University Of Illinois | Methods for treating sleep disorders by cholecystokinin (CCK) receptor B antagonists |
| WO2007047575A2 (en) * | 2005-10-14 | 2007-04-26 | The Board Of Trustees Of The University Of Illinois | Pharmacological treatments for sleep-related breathing disorders |
| EP2142183A2 (en) * | 2007-04-09 | 2010-01-13 | Sepracor Inc. | Methods and compositions comprising desvenlafaxine or duloxetine for treating sleep-related breathing disorders |
| WO2015077572A1 (en) | 2013-11-22 | 2015-05-28 | CL BioSciences LLC | Gastrin antagonists (eg yf476, netazepide) for treatment and prevention of osteoporosis |
| CN106413541B (zh) * | 2014-01-08 | 2021-04-06 | 纽罗荣动力学公司 | 用于诊断睡眠的系统和方法 |
| EP3537961B1 (en) | 2016-11-10 | 2025-06-25 | The Research Foundation for The State University of New York | System, method and biomarkers for airway obstruction |
| US20250009720A1 (en) * | 2021-11-11 | 2025-01-09 | Apnimed, Inc. (Delaware) | Methods and compositions for treating sleep apnea |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4820834A (en) | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
| IL104853A (en) | 1992-02-27 | 1997-11-20 | Yamanouchi Pharma Co Ltd | Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them |
| JP2862675B2 (ja) | 1993-07-26 | 1999-03-03 | フアイザー・インコーポレイテツド | 選択的コレシストキニン−ｂ受容体拮抗薬としてのテトラヒドロ−１ｈ−ベンゾアゼピノンおよびヘキサヒドロアゼピノン |
| GB2282595A (en) | 1993-08-25 | 1995-04-12 | Yamanouchi Pharma Co Ltd | Benzodiazepine derivatives |
| IT1286141B1 (it) | 1996-07-02 | 1998-07-07 | Rotta Research Lab | Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico. |
| US20040198723A1 (en) * | 2002-01-22 | 2004-10-07 | Karen Gibson | Method of treatment |
| US8053413B2 (en) * | 2005-06-06 | 2011-11-08 | The Board Of Trustees Of The University Of Illinois | Methods for treating sleep disorders by cholecystokinin (CCK) receptor B antagonists |
-
2006
- 2006-06-06 US US11/916,563 patent/US8053413B2/en not_active Expired - Fee Related
- 2006-06-06 AU AU2006255047A patent/AU2006255047B2/en not_active Ceased
- 2006-06-06 CA CA2610866A patent/CA2610866C/en not_active Expired - Fee Related
- 2006-06-06 ES ES06772299T patent/ES2423412T3/es active Active
- 2006-06-06 JP JP2008515832A patent/JP5197361B2/ja not_active Expired - Fee Related
- 2006-06-06 WO PCT/US2006/021929 patent/WO2006133197A1/en not_active Ceased
- 2006-06-06 EP EP06772299.1A patent/EP1898921B1/en active Active
-
2011
- 2011-09-21 US US13/238,305 patent/US20120010198A1/en not_active Abandoned
-
2013
- 2013-10-21 US US14/058,565 patent/US20140045755A1/en not_active Abandoned
Non-Patent Citations (2)
| Title |
|---|
| Bennet L et al, 1990. "Apneic effects of cholecystokinin in unanaesthetized fetal sheep" Journal of Developmental Physiology. 14:229-233 * |
| DeMesquita S et al, 1986. "Effect of Chronic Intracerebroventricular Infusion of Cholecystokinin on Respiration and Sleep" Brain Research. 378:127-132 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20080200367A1 (en) | 2008-08-21 |
| US20120010198A1 (en) | 2012-01-12 |
| EP1898921A4 (en) | 2008-11-05 |
| EP1898921A1 (en) | 2008-03-19 |
| AU2006255047A1 (en) | 2006-12-14 |
| EP1898921B1 (en) | 2013-05-01 |
| WO2006133197A9 (en) | 2007-03-22 |
| JP2008542443A (ja) | 2008-11-27 |
| ES2423412T3 (es) | 2013-09-20 |
| CA2610866A1 (en) | 2006-12-14 |
| US20140045755A1 (en) | 2014-02-13 |
| WO2006133197A1 (en) | 2006-12-14 |
| CA2610866C (en) | 2015-07-28 |
| JP5197361B2 (ja) | 2013-05-15 |
| US8053413B2 (en) | 2011-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |