CA2610249A1 - Procedes de mesure non invasive de niveaux d'analyte chez un patient - Google Patents
Procedes de mesure non invasive de niveaux d'analyte chez un patient Download PDFInfo
- Publication number
- CA2610249A1 CA2610249A1 CA002610249A CA2610249A CA2610249A1 CA 2610249 A1 CA2610249 A1 CA 2610249A1 CA 002610249 A CA002610249 A CA 002610249A CA 2610249 A CA2610249 A CA 2610249A CA 2610249 A1 CA2610249 A1 CA 2610249A1
- Authority
- CA
- Canada
- Prior art keywords
- oct
- scattering
- tissue
- coefficient
- profile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims abstract description 73
- 239000012491 analyte Substances 0.000 title claims abstract description 25
- 239000008103 glucose Substances 0.000 claims abstract description 100
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 98
- 210000004369 blood Anatomy 0.000 claims abstract description 87
- 239000008280 blood Substances 0.000 claims abstract description 87
- 238000012014 optical coherence tomography Methods 0.000 claims description 131
- 238000005259 measurement Methods 0.000 claims description 69
- 238000010521 absorption reaction Methods 0.000 claims description 53
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 27
- 230000000875 corresponding effect Effects 0.000 claims description 18
- 210000004204 blood vessel Anatomy 0.000 claims description 15
- 230000002596 correlated effect Effects 0.000 claims description 8
- 230000002792 vascular Effects 0.000 claims description 8
- 102000001554 Hemoglobins Human genes 0.000 claims description 6
- 108010054147 Hemoglobins Proteins 0.000 claims description 6
- 230000002238 attenuated effect Effects 0.000 claims description 3
- 230000002500 effect on skin Effects 0.000 claims description 3
- 238000003384 imaging method Methods 0.000 abstract description 8
- 210000001519 tissue Anatomy 0.000 description 83
- 210000003491 skin Anatomy 0.000 description 33
- 230000000694 effects Effects 0.000 description 20
- 230000036571 hydration Effects 0.000 description 16
- 238000006703 hydration reaction Methods 0.000 description 16
- 230000008859 change Effects 0.000 description 14
- 238000012544 monitoring process Methods 0.000 description 9
- 239000000470 constituent Substances 0.000 description 7
- 230000000065 osmolyte Effects 0.000 description 7
- 210000003722 extracellular fluid Anatomy 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 5
- 230000031700 light absorption Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 2
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 2
- 238000000149 argon plasma sintering Methods 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000003114 blood coagulation factor Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 210000004207 dermis Anatomy 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 238000000502 dialysis Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000010606 normalization Methods 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 238000012935 Averaging Methods 0.000 description 1
- 206010007559 Cardiac failure congestive Diseases 0.000 description 1
- 208000002249 Diabetes Complications Diseases 0.000 description 1
- 206010012655 Diabetic complications Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 229940127090 anticoagulant agent Drugs 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000004159 blood analysis Methods 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 230000008081 blood perfusion Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000005670 electromagnetic radiation Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000001631 haemodialysis Methods 0.000 description 1
- 230000000322 hemodialysis Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000002570 interstitial cell Anatomy 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012634 optical imaging Methods 0.000 description 1
- 238000000711 polarimetry Methods 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 208000002815 pulmonary hypertension Diseases 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000000790 scattering method Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 230000037067 skin hydration Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Optics & Photonics (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68672105P | 2005-06-02 | 2005-06-02 | |
| US60/686,721 | 2005-06-02 | ||
| PCT/US2006/021535 WO2006130847A2 (fr) | 2005-06-02 | 2006-06-02 | Procedes de mesure non invasive de niveaux d'analyte chez un patient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2610249A1 true CA2610249A1 (fr) | 2006-12-07 |
Family
ID=37482354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002610249A Abandoned CA2610249A1 (fr) | 2005-06-02 | 2006-06-02 | Procedes de mesure non invasive de niveaux d'analyte chez un patient |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1901645A2 (fr) |
| JP (1) | JP2008546430A (fr) |
| AU (1) | AU2006252398A1 (fr) |
| CA (1) | CA2610249A1 (fr) |
| WO (1) | WO2006130847A2 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3505044A1 (fr) * | 2017-12-29 | 2019-07-03 | Samsung Electronics Co., Ltd. | Appareil et procédé de mesure de composant biologique |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5148054B2 (ja) * | 2005-09-15 | 2013-02-20 | オリンパスメディカルシステムズ株式会社 | 撮像システム |
| JP2007075366A (ja) * | 2005-09-14 | 2007-03-29 | Olympus Medical Systems Corp | 赤外観察システム |
| JP5062816B2 (ja) * | 2007-02-09 | 2012-10-31 | 株式会社松風 | 反射型断層撮影装置 |
| JP5684443B2 (ja) * | 2007-06-06 | 2015-03-11 | 横河電機株式会社 | 生体成分測定装置 |
| CN103429153A (zh) | 2010-11-03 | 2013-12-04 | 华盛顿大学商业中心 | 活体内的组织氧化的确定 |
| JP5783564B2 (ja) * | 2011-08-15 | 2015-09-24 | 国立大学法人神戸大学 | 三次元光散乱体の実効散乱係数の算定方法 |
| CN103340635B (zh) * | 2013-05-30 | 2015-03-04 | 苏州光环科技有限公司 | 基于oct的光学参数与血糖浓度三维相关性的计算方法 |
| JPWO2016063547A1 (ja) | 2014-10-24 | 2017-08-03 | 日本電気株式会社 | 排泄物の分析装置、該分析装置を備えた便器および排泄物の分析方法 |
| EP3534147B1 (fr) | 2016-10-28 | 2022-03-16 | FUJIFILM Corporation | Dispositif d'imagerie tomographique par cohérence optique et procédé de mesure |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL107396A (en) * | 1992-11-09 | 1997-02-18 | Boehringer Mannheim Gmbh | Method and apparatus for analytical determination of glucose in a biological matrix |
| TW275570B (fr) * | 1994-05-05 | 1996-05-11 | Boehringer Mannheim Gmbh | |
| US6725073B1 (en) * | 1999-08-17 | 2004-04-20 | Board Of Regents, The University Of Texas System | Methods for noninvasive analyte sensing |
-
2006
- 2006-06-02 CA CA002610249A patent/CA2610249A1/fr not_active Abandoned
- 2006-06-02 WO PCT/US2006/021535 patent/WO2006130847A2/fr active Application Filing
- 2006-06-02 EP EP06772010A patent/EP1901645A2/fr not_active Withdrawn
- 2006-06-02 JP JP2008514918A patent/JP2008546430A/ja not_active Withdrawn
- 2006-06-02 AU AU2006252398A patent/AU2006252398A1/en not_active Abandoned
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3505044A1 (fr) * | 2017-12-29 | 2019-07-03 | Samsung Electronics Co., Ltd. | Appareil et procédé de mesure de composant biologique |
| US11013412B2 (en) | 2017-12-29 | 2021-05-25 | Samsung Electronics Co., Ltd. | Biological component measuring apparatus and biological component measuring method |
| US11607133B2 (en) | 2017-12-29 | 2023-03-21 | Samsung Electronics Co., Ltd. | Biological component measuring apparatus and biological component measuring method |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006252398A1 (en) | 2006-12-07 |
| WO2006130847A2 (fr) | 2006-12-07 |
| EP1901645A2 (fr) | 2008-03-26 |
| WO2006130847A3 (fr) | 2009-04-16 |
| JP2008546430A (ja) | 2008-12-25 |
| AU2006252398A2 (en) | 2008-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |