CA2600134A1 - Methods and compositions for treating cancer - Google Patents
Methods and compositions for treating cancer Download PDFInfo
- Publication number
- CA2600134A1 CA2600134A1 CA002600134A CA2600134A CA2600134A1 CA 2600134 A1 CA2600134 A1 CA 2600134A1 CA 002600134 A CA002600134 A CA 002600134A CA 2600134 A CA2600134 A CA 2600134A CA 2600134 A1 CA2600134 A1 CA 2600134A1
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- Prior art keywords
- cancer
- ebselen
- allopurinol
- cisplatin
- mammal
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| PCT/US2006/008201 WO2006096759A2 (en) | 2005-03-08 | 2006-03-08 | Methods and compositions for treating cancer |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013059927A1 (en) * | 2011-10-28 | 2013-05-02 | The Royal Institute For The Advancement Of Learning/Mcgill University | Compounds targeting the cell invasion protein complex, their pharmaceutical compositions and methods of use thereof |
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| WO2008100628A2 (en) * | 2007-02-16 | 2008-08-21 | Synvista Therapeutics, Inc. | Glutathione peroxidase mimetics for treatment of neurodegenerative, pulmonary and inflammatory diseases |
| US20080207679A1 (en) * | 2007-02-16 | 2008-08-28 | Noah Berkowitz | Glutathione peroxidase mimetics for the treatment of dermatoses |
| GB0916010D0 (en) * | 2009-09-11 | 2009-10-28 | Isis Innovation | JMJD2 demethylase inhibitors |
| GB201102248D0 (en) | 2011-02-09 | 2011-03-23 | Isis Innovation | Treatment of bipolar disorder |
| WO2014144850A1 (en) * | 2013-03-15 | 2014-09-18 | Genentech, Inc. | Methods of treating cancer and preventing cancer drug resistance |
| WO2015200358A1 (en) | 2014-06-24 | 2015-12-30 | The Board Of Trustees Of The Leland Stanford Junior University | Use of small molecules for the treatment of clostridium difficile toxicity |
| GB2550110A (en) * | 2016-04-28 | 2017-11-15 | Univ Oxford Innovation Ltd | Treatment of impulsivity-related disorders |
| CN107714650A (zh) * | 2016-08-11 | 2018-02-23 | 杭州健昵福生物科技有限公司 | 一种含谷氨酰胺代谢抑制剂脂质体及其药物组合物与用途 |
| GB201717629D0 (en) | 2017-10-26 | 2017-12-13 | Univ Oxford Innovation Ltd | Treatment of unipolar depressive disorder |
| US20210267984A1 (en) * | 2018-09-03 | 2021-09-02 | Wei Zhu | Application of allopurinol in preparation of drug for treating cancer with high expression of paics gene |
| IT202200018339A1 (it) * | 2022-09-08 | 2024-03-08 | Univ Degli Studi Di Trento | Composti del selenio e dello zolfo quali inibitori del riconoscimento degli RNA modificati da N6-metiladenosina da parte delle proteine YTHDF |
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| DE3027073C2 (de) * | 1980-07-17 | 1985-03-07 | A. Nattermann & Cie GmbH, 5000 Köln | Pharmazeutische Präparate, enthaltend 2-Phenyl-1,2-benzisoselenazol-3(2H)-on |
| DE3670635D1 (de) * | 1985-04-27 | 1990-05-31 | Nattermann A & Cie | Neue benzisoselenazolonyl-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate. |
| DE3638124C2 (de) * | 1986-11-08 | 1996-09-05 | Nattermann A & Cie | Neue pharmazeutische Verwendung von Ebselen |
| US5385726A (en) * | 1990-08-06 | 1995-01-31 | Rhone-Poulenc Rorer Gmbh | Use of 2-phenyl-1,2-benzisoselenazol-3-(2H)-one |
| DE4024885C2 (de) * | 1990-08-06 | 2002-07-18 | Nattermann A & Cie | Verwendung von 2-Phenyl-1,2-benzisoselenazol-3(2H)-on |
| US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| US5919815A (en) * | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
| US6177434B1 (en) * | 1997-12-16 | 2001-01-23 | The United States Of America As Represented By The Secretary Of The Navy | Prevention or reversal of sensorineural hearing loss (SNHL) through biologic mechanisms |
| US6093743A (en) * | 1998-06-23 | 2000-07-25 | Medinox Inc. | Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor |
| US6601580B1 (en) * | 2000-06-28 | 2003-08-05 | The General Hospital Corporation | Enhancing therapeutic effectiveness of nitric oxide inhalation |
| KR100949318B1 (ko) * | 2001-11-29 | 2010-03-23 | 사운드 파마슈티칼스 인코퍼레이티드 | 화학요법의 바람직하지 않은 작용을 개선하기 위한 방법과조성물 |
| EP1463507A1 (en) * | 2001-12-19 | 2004-10-06 | SmithKline Beecham Corporation | Thienopyrimidine compounds as protein tyrosine kinase inhibitors |
| ES2497716T3 (es) * | 2002-01-04 | 2014-09-23 | Sound Pharmaceuticals Incorporated | Composiciones para utilizar en métodos destinados a tratar la pérdida auditiva |
| US6702850B1 (en) * | 2002-09-30 | 2004-03-09 | Mediplex Corporation Korea | Multi-coated drug-eluting stent for antithrombosis and antirestenosis |
| JP4532408B2 (ja) * | 2003-03-13 | 2010-08-25 | 田辺三菱製薬株式会社 | 腫瘍形成抑制剤 |
| US20050147978A1 (en) * | 2003-12-30 | 2005-07-07 | Jose Remacle | Method for quantitative determination of multi-drug resistance in tumors |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013059927A1 (en) * | 2011-10-28 | 2013-05-02 | The Royal Institute For The Advancement Of Learning/Mcgill University | Compounds targeting the cell invasion protein complex, their pharmaceutical compositions and methods of use thereof |
| US9085598B2 (en) | 2011-10-28 | 2015-07-21 | The Royal Institution For The Advancement Of Learning/Mcgill University | Compounds targeting the cell invasion protein complex, their pharmaceutical compositions and methods of use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| US20110020470A1 (en) | 2011-01-27 |
| AU2006220626A1 (en) | 2006-09-14 |
| KR20070113262A (ko) | 2007-11-28 |
| WO2006096759A2 (en) | 2006-09-14 |
| EP1855662A4 (en) | 2009-12-23 |
| EP1855662A2 (en) | 2007-11-21 |
| WO2006096759A3 (en) | 2007-04-05 |
| CN101160121B (zh) | 2012-05-23 |
| US20060211745A1 (en) | 2006-09-21 |
| CN101160121A (zh) | 2008-04-09 |
| JP2008533021A (ja) | 2008-08-21 |
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