CA2586511C - Immunoassays for lamotrigine - Google Patents

Immunoassays for lamotrigine Download PDF

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Publication number
CA2586511C
CA2586511C CA2586511A CA2586511A CA2586511C CA 2586511 C CA2586511 C CA 2586511C CA 2586511 A CA2586511 A CA 2586511A CA 2586511 A CA2586511 A CA 2586511A CA 2586511 C CA2586511 C CA 2586511C
Authority
CA
Canada
Prior art keywords
lamotrigine
antibody
analog
group
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2586511A
Other languages
English (en)
French (fr)
Other versions
CA2586511A1 (en
Inventor
Anlong Ouyang
Lili Arabshahi
Mark Roberts
Melissa Wall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seradyn Inc
Original Assignee
Seradyn Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seradyn Inc filed Critical Seradyn Inc
Publication of CA2586511A1 publication Critical patent/CA2586511A1/en
Application granted granted Critical
Publication of CA2586511C publication Critical patent/CA2586511C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075Two hetero atoms, in positions 3 and 5
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9473Anticonvulsants, e.g. phenobarbitol, phenytoin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/13Tracers or tags
CA2586511A 2004-10-25 2005-10-21 Immunoassays for lamotrigine Expired - Fee Related CA2586511C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US62176404P 2004-10-25 2004-10-25
US60/621,764 2004-10-25
US11/254,637 2005-10-20
US11/254,637 US7678551B2 (en) 2004-10-25 2005-10-20 Immunoassays for lamotrigine
PCT/US2005/038258 WO2006047451A2 (en) 2004-10-25 2005-10-21 Immunoassays for lamotrigine

Publications (2)

Publication Number Publication Date
CA2586511A1 CA2586511A1 (en) 2006-05-04
CA2586511C true CA2586511C (en) 2014-11-25

Family

ID=36228347

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2586511A Expired - Fee Related CA2586511C (en) 2004-10-25 2005-10-21 Immunoassays for lamotrigine

Country Status (6)

Country Link
US (2) US7678551B2 (US07678551-20100316-C00001.png)
EP (1) EP1805515B1 (US07678551-20100316-C00001.png)
JP (1) JP4902544B2 (US07678551-20100316-C00001.png)
AU (1) AU2005299537B2 (US07678551-20100316-C00001.png)
CA (1) CA2586511C (US07678551-20100316-C00001.png)
WO (1) WO2006047451A2 (US07678551-20100316-C00001.png)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2239573A3 (en) * 2005-03-30 2011-02-08 Saladax Biomedical Inc. Doxorubicin derivatives and conjugates for doxorubicin immunoassay
US8828665B2 (en) 2007-02-16 2014-09-09 Ark Diagnostics, Inc. Compounds and methods for use in detecting gabapentin
EP2596805B1 (en) * 2008-02-01 2021-10-27 Ascendis Pharma A/S Prodrug comprising a drug-linker conjugate
KR101799113B1 (ko) 2009-05-13 2017-11-17 넥타르 테라퓨틱스 올리고머를 함유하는 치환된 방향족 트리아진 화합물
US8785661B2 (en) 2009-05-13 2014-07-22 Nektar Therapeutics Oligome-containing pyrrolidine compounds
PE20120918A1 (es) 2009-07-31 2012-08-14 Sanofi Aventis Deutschland Profarmacos que comprenden un conjugado de insulina-conector
RU2556340C2 (ru) 2009-07-31 2015-07-10 Санофи-Авентис Дойчланд Гмбх Композиция инсулина длительного действия
EP2438930A1 (en) 2010-09-17 2012-04-11 Sanofi-Aventis Deutschland GmbH Prodrugs comprising an exendin linker conjugate
US9726681B2 (en) * 2013-08-07 2017-08-08 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting cortisol
WO2015092819A2 (en) * 2013-12-21 2015-06-25 Nektar Therapeutics (India) Pvt. Ltd. Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5- amine
CN108840933A (zh) * 2018-07-16 2018-11-20 夏泉 一种拉莫三嗪单克隆抗体的制备方法
CN108918851B (zh) * 2018-07-16 2020-04-07 夏泉 一种拉莫三嗪胶体金试纸条的制备方法
JP7077175B2 (ja) * 2018-08-07 2022-05-30 キヤノン株式会社 自動分析装置、自動分析方法、および、プログラム
CN110967481B (zh) * 2019-12-06 2023-07-04 苏州博源医疗科技有限公司 一种拉莫三嗪衍生物、其制备方法及其在均相酶免疫检测试剂中的应用
CN112946254B (zh) * 2021-01-18 2024-03-15 上海云泽生物科技有限公司 一种胶乳增强竞争免疫比浊检测方法及试剂盒

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4593089A (en) 1980-07-30 1986-06-03 Abbott Laboratories Fluorescent polarization immunoassay utilizing substituted triazinylaminofluorescein aminoglycosides
US4668640A (en) 1981-12-11 1987-05-26 Abbott Laboratories Fluorescence polarization immunoassay utilizing substituted carboxyfluoresceins
US4492762A (en) 1981-12-11 1985-01-08 Abbott Laboratories Fluorescent polarization immunoassays
US5604091A (en) 1984-03-01 1997-02-18 Microgenics Corporation Methods for protein binding enzyme complementation
US4708929A (en) 1984-10-29 1987-11-24 Microgenics Corporation Methods for protein binding enzyme complementation assays
US5120653A (en) 1985-04-08 1992-06-09 Microgenics Corporation Vector comprising DNA sequence coding for enzyme-donor polypeptide
US4751190A (en) 1985-07-22 1988-06-14 Abbott Laboratories Fluorescence polarization immunoassay and reagents for use therein
US4847209A (en) 1987-11-09 1989-07-11 Miles Inc. Latex agglutination immunoassay in the presence of hemoglobin
US6448091B1 (en) 1988-11-03 2002-09-10 Igen International, Inc. Method and apparatus for improved luminescence assays using particle concentration chemiluminescence detection
US5798083A (en) 1988-11-03 1998-08-25 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration and chemiluminescence detection
DE4211351A1 (de) 1992-04-04 1993-10-07 Behringwerke Ag Verfahren zur Analyse partikelverstärkter Agglutinationsreaktionen auf Zentrifugalanalysatoren durch Bestimmung der Trübungsaufhellung
DE4444002A1 (de) 1994-12-10 1996-06-13 Behringwerke Ag Immunoassays für Haptene und hierfür verwendbare Haptentracer-Antikörper-Komplexe sowie Verfahren zur Herstellung derselben
CA2244326C (en) 1997-08-11 2006-03-28 Shinichi Eda Microparticle enhanced light scattering agglutination assay and microparticle reagents therefor
GB9812413D0 (en) 1998-06-10 1998-08-05 Glaxo Group Ltd Compound and its use
US6232082B1 (en) * 1998-12-01 2001-05-15 Nabi Hapten-carrier conjugates for treating and preventing nicotine addiction
DE60023998T2 (de) 1999-07-30 2006-08-10 Mitsubishi Chemical Corp. Immunoassay
RU2181297C2 (ru) * 2000-06-20 2002-04-20 Эпштейн Олег Ильич Способ лечения патологического синдрома и лекарственное средство
GB0130535D0 (en) * 2001-12-20 2002-02-06 Randox Lab Ltd Haptens immunogens antibodies and conjugates to oxycodone and its metabolites
US7451190B2 (en) * 2003-11-26 2008-11-11 Yahoo! Inc. Associating multiple visibility profiles with a user of a real-time communication system
US20060115865A1 (en) 2004-10-25 2006-06-01 Anlong Ouyang Lamotrigine analogs

Also Published As

Publication number Publication date
EP1805515A2 (en) 2007-07-11
US7678551B2 (en) 2010-03-16
WO2006047451A2 (en) 2006-05-04
AU2005299537A1 (en) 2006-05-04
AU2005299537B2 (en) 2012-01-19
EP1805515A4 (en) 2009-01-21
US8592564B2 (en) 2013-11-26
CA2586511A1 (en) 2006-05-04
JP4902544B2 (ja) 2012-03-21
JP2008518234A (ja) 2008-05-29
EP1805515B1 (en) 2014-05-21
US20060172356A1 (en) 2006-08-03
WO2006047451A3 (en) 2007-04-19
US20100209416A1 (en) 2010-08-19

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Effective date: 20191021