CA2585359C - Gaba-steroid antagonists and their use for the treatment of cns disorders - Google Patents
Gaba-steroid antagonists and their use for the treatment of cns disorders Download PDFInfo
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- CA2585359C CA2585359C CA2585359A CA2585359A CA2585359C CA 2585359 C CA2585359 C CA 2585359C CA 2585359 A CA2585359 A CA 2585359A CA 2585359 A CA2585359 A CA 2585359A CA 2585359 C CA2585359 C CA 2585359C
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- pregnan
- gaba
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- diol
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62951104P | 2004-11-18 | 2004-11-18 | |
| US60/629,511 | 2004-11-18 | ||
| PCT/SE2005/001671 WO2006054938A1 (en) | 2004-11-18 | 2005-11-07 | Gaba-steroid antagonists and their use for the treatment of cns disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2585359A1 CA2585359A1 (en) | 2006-05-26 |
| CA2585359C true CA2585359C (en) | 2013-01-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2585359A Expired - Fee Related CA2585359C (en) | 2004-11-18 | 2005-11-07 | Gaba-steroid antagonists and their use for the treatment of cns disorders |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8114860B2 (OSRAM) |
| EP (1) | EP1812009B1 (OSRAM) |
| JP (1) | JP4914368B2 (OSRAM) |
| CN (1) | CN101076340B (OSRAM) |
| AU (1) | AU2005307151B2 (OSRAM) |
| BR (1) | BRPI0518359A2 (OSRAM) |
| CA (1) | CA2585359C (OSRAM) |
| DK (1) | DK1812009T3 (OSRAM) |
| ES (1) | ES2423493T3 (OSRAM) |
| MX (1) | MX2007006032A (OSRAM) |
| WO (1) | WO2006054938A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4914368B2 (ja) * | 2004-11-18 | 2012-04-11 | ウメクライン アーベー | Ｇａｂａ−ステロイド拮抗剤およびｃｎｓ疾患の治療のためのその使用 |
| PL2711371T3 (pl) * | 2006-11-21 | 2018-06-29 | Asarina Pharma Ab | Zastosowanie steroidów pregnanowych i androstanowych do wytwarzania kompozycji farmaceutycznej do leczenia zaburzeń oun |
| CN101585862B (zh) * | 2008-05-20 | 2014-12-17 | 梅克芳股份公司 | 甾族化合物 |
| US20110086828A1 (en) * | 2009-10-07 | 2011-04-14 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Treatment of alcohol abuse and alcoholism using modulators of neurosteroid binding sites on gabaa receptors |
| WO2011087441A1 (en) | 2010-01-14 | 2011-07-21 | Umecrine Mood Ab | A pharmaceutical composition comprising 3-beta-hydroxy-5-alpha-pregnan-20-one with improved storage and solubility properties |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4614499A (en) * | 1985-04-29 | 1986-09-30 | Universite Laval | Simulator for use as a neurosurgical aid in determining potential paths for the implantation of probes through the human body |
| ATE307592T1 (de) * | 1998-03-11 | 2005-11-15 | Torbjoern Backstroem | Epiallopregnanolon zur behandlung von krankheiten des cns |
| FR2806303B1 (fr) | 2000-03-17 | 2002-09-27 | Inst Nat Sante Rech Med | Composes capables de se lier a des proteines constituantes ou associees aux elements du cytosquelette et leurs applications pour la fabrication de medicaments |
| US20030125311A1 (en) * | 2000-03-17 | 2003-07-03 | Etienne-Emile Baulieu | Compounds capable of binding with the cytoskeleton |
| SE0104423D0 (sv) * | 2001-12-27 | 2001-12-27 | Umecrine Ab | Pregnane steroids and their use in the treatment of CNS disorders |
| JP4914368B2 (ja) | 2004-11-18 | 2012-04-11 | ウメクライン アーベー | Ｇａｂａ−ステロイド拮抗剤およびｃｎｓ疾患の治療のためのその使用 |
-
2005
- 2005-11-07 JP JP2007542970A patent/JP4914368B2/ja not_active Expired - Fee Related
- 2005-11-07 WO PCT/SE2005/001671 patent/WO2006054938A1/en not_active Ceased
- 2005-11-07 CN CN2005800394888A patent/CN101076340B/zh not_active Expired - Fee Related
- 2005-11-07 BR BRPI0518359-6A patent/BRPI0518359A2/pt not_active IP Right Cessation
- 2005-11-07 DK DK05801885.4T patent/DK1812009T3/da active
- 2005-11-07 MX MX2007006032A patent/MX2007006032A/es active IP Right Grant
- 2005-11-07 ES ES05801885T patent/ES2423493T3/es not_active Expired - Lifetime
- 2005-11-07 US US11/791,160 patent/US8114860B2/en not_active Expired - Fee Related
- 2005-11-07 CA CA2585359A patent/CA2585359C/en not_active Expired - Fee Related
- 2005-11-07 EP EP05801885.4A patent/EP1812009B1/en not_active Expired - Lifetime
- 2005-11-07 AU AU2005307151A patent/AU2005307151B2/en not_active Ceased
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2012
- 2012-02-13 US US13/372,389 patent/US8372824B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK1812009T3 (da) | 2013-08-05 |
| US20120142657A1 (en) | 2012-06-07 |
| ES2423493T3 (es) | 2013-09-20 |
| CN101076340B (zh) | 2011-01-12 |
| US20080070876A1 (en) | 2008-03-20 |
| EP1812009B1 (en) | 2013-05-15 |
| AU2005307151B2 (en) | 2011-10-20 |
| US8114860B2 (en) | 2012-02-14 |
| JP2008525317A (ja) | 2008-07-17 |
| EP1812009A1 (en) | 2007-08-01 |
| US8372824B2 (en) | 2013-02-12 |
| JP4914368B2 (ja) | 2012-04-11 |
| CN101076340A (zh) | 2007-11-21 |
| CA2585359A1 (en) | 2006-05-26 |
| BRPI0518359A2 (pt) | 2008-11-18 |
| WO2006054938A1 (en) | 2006-05-26 |
| MX2007006032A (es) | 2007-10-17 |
| EP1812009A4 (en) | 2010-08-11 |
| AU2005307151A1 (en) | 2006-05-26 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20201109 |